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Lignans

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ISBN: 9783038979081 / 9783038979098 Year: Pages: 384 DOI: 10.3390/books978-3-03897-909-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General) --- Organic Chemistry
Added to DOAB on : 2019-06-26 10:09:00
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Abstract

Lignans are a class of natural products found mainly in plants. They have a wide variety of structures and exhibit a range of potent biological activities. Lignans are also well-known components of a number of widely eaten foods and are frequently studied for their dietary impact. Owing to these factors, lignans have been extensively studied by scientists from a large number of disciplines. This collection of research and review articles describes topics ranging in scope from the recent isolation and structural elucidation of new lignans, strategies towards the chemical synthesis of lignans, assessment of their biological activities and potential for further therapeutic development. Research showing the impact of lignans in the food and agricultural industries is also presented.

Keywords

lignans --- chemometrics --- neolignans --- flavonolignans --- chemical space --- drug-like --- Lespedeza cuneata --- lignan glycoside --- flavonoid glycoside --- cytotoxicity --- adipocyte and osteoblast differentiation --- Bursera --- Burseraceae --- lignans --- lignan --- molecular dynamics --- intermolecular interactions --- graph theory --- lignans --- heilaohu --- tujia ethnomedicine --- chemical characterization --- cytotoxicity --- antioxidant --- cultivar --- environment --- flax --- flavonol --- genetic --- hydroxycinnamic acid --- lignan --- seed --- aryldihydronaphthalene lignan --- arylnaphthalene lignan --- oxidation --- synthesis --- lignans --- dibenzyl butyrolactones --- anti-proliferative --- acyl-Claisen --- stereoselective synthesis --- Schisandra rubriflora --- Schisandra chinensis --- red-flowered Chinese magnolia vine --- Chinese magnolia vine --- lignans --- phytochemical analysis --- UHPLC-MS/MS --- anti-inflammatory activity --- LOX --- COX --- sPLA2 --- lignans --- neolignans --- Lauraceae --- chemical components --- chemical structures --- dietary lignans --- national databases --- food groups --- dietary intake --- harmonized databases --- lignans --- in silico studies --- podophyllotoxin --- antibacterial activity --- acetylcholinesterase inhibitors --- antioxidant activity --- cytotoxicity --- natural products --- total synthesis --- lignan --- Bursera fagaroides --- podophyllotoxin-type lignans --- cell cycle --- cell migration --- epiboly --- microtubules --- F-actin --- cancer --- lignans --- animal health --- cattle --- enterolignan --- human health --- pharmacokinetic --- ruminant --- secoisolariciresinol diglucoside --- Lignan --- bitterness --- taste-active compound --- quantification --- oak ageing --- lignans --- norlignans --- 9-norlignans --- semisynthesis --- hydroxymatairesinol --- bioactivity --- lignans --- oxidation --- lignans --- diet --- antioxidants --- health promotion --- chronic diseases --- Schisandrae Chinensis Fructus --- wild --- cultivated --- multiple bioactive components --- simultaneous quantitation

Marine Anti-inflammatory Agents

Authors: ---
ISBN: 9783039215720 / 9783039215737 Year: Pages: 248 DOI: 10.3390/books978-3-03921-573-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2019-12-09 11:49:16
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Abstract

Acute inflammation is a highly regulated process, and its dysregulation can lead to the development of a chronic inflammatory state which is believed to play a main role in the pathogenesis of many diseases, including cancer. In recent years, the need to find new anti-inflammatory molecules has raised the scientific community´s interest for marine natural products. In this regard, the marine environment represents a source for isolating a wealth of bioactive compounds. In this Special Issue, the reported products have been obtained from microalgae, sea cucumber, octopus, squid, red alga-derived fungus, cnidarians, hard-shelled mussel, and sponges.

Keywords

THP-1 macrophages --- anti-inflammatory --- TLR4 --- NF-?B --- MAPK --- SPR analysis --- glycolipids --- MGDG --- skin --- inflammation --- epidermal hyperplasia --- microalgae --- Isochrysis galbana --- Frondanol --- Cucumaria frondosa --- DSS colitis --- colon inflammation --- zoantharia --- Tropical Eastern Pacific --- Zoanthus pulchellus --- zoanthamine --- inflammation --- fucoxanthin --- inflammation --- epidermal hyperplasia --- UVB --- photoprotection --- 6-bromoindole --- Geodia barretti --- anti-inflammatory activity --- dendritic cells --- T cell differentiation --- poor blood circulation --- Ecklonia cava --- phlorotannins --- pyrogallol-phloroglucinol-6,6-bieckol --- functional ingredients --- endothelial cell death --- vascular smooth muscle cell proliferation and migration --- inflammation --- anti-inflammatory --- bioactive molecules --- microalgae --- polysaccharides --- carotenoids --- polyunsaturated fatty acids --- fucoxanthin --- ultraviolet B --- denervation --- seafood waste --- polyunsaturated fatty acid --- NO inhibition --- fish oil --- marine nutraceuticals --- fish oil --- omega-3 --- eicosapentaenoic acid --- docosahexaenoic acid --- inflammation --- eicosanoid --- cytokine --- surgery --- critical illness --- parenteral nutrition --- signal transducer and activator of transcription 3 (STAT3) --- matrix metalloproteinases-9 (MMP-9) --- interleukin (IL) --- lipopolysaccharide (LPS) --- acute sickness behavior --- acute lung injury (ALI) --- prostaglandins --- clavulones --- punaglandins --- thromboxane --- inflammation --- marine vertebrates --- marine invertebrates --- diatoms --- macroalgae --- fucoxanthin --- rosmarinic acid --- NRLP3 --- inflammasome --- anti-oxidative --- anti-inflammatory --- photo-protection --- UVB

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MDPI - Multidisciplinary Digital Publishing Institute (2)


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CC by-nc-nd (2)


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eng (2)


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2019 (2)