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Sex and gender in biomedicine - theories, methodologies, results

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ISBN: 9783941875265 Year: Language: English
Publisher: Universitätsverlag Göttingen
Subject: Medicine (General) --- Gender Studies
Added to DOAB on : 2016-06-21 11:01:31
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Sex and gender in biomedicine are innovative research concepts of theoretical and clinical medicine that enable a better understanding of health and disease, evidence-based knowledge, effective therapies, and better health outcomes for women and men. Gender Medicine stimulates new ways of doing research: that is to consider sex and gender at all levels of research, from basic research into gene polymorphisms to health behaviour. New research questions have been put forward that focus not on differences per se but on the development of differences. In this book, contributions from the field of neuroscience, addiction research, and organ transplantation exemplify concepts, approaches, methods and results in the field.

Plasma Modified Textiles for Biomedical Applications (Book chapter)

Authors: --- ---
ISBN: 9789535121411 Year: DOI: 10.5772/59770 Language: English
Publisher: IntechOpen Grant: FP7 Ideas: European Research Council - 279022
Subject: Science (General)
Added to DOAB on : 2019-01-17 11:48:00
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In the textile market industry, technical textiles are one of the fastest growing businesses. Part of that industry consists of textiles for medical and healthcare applications and are responsible for a continuous increase in its market potential [1]. Next to their need in hospital environments, there is a growing demand in other sectors such as the food and hotel industry, due to stricter hygiene regulations. In most cases biomedical textile meets a well-defined set of requirements such as minimizing non-specific protein adsorption, drug delivery coatings or the presence of active functional coatings and most importantly excellent biocompatibility (blood-, tissue-or cyto-compatibility) [2]. In general there are very few materials meeting all these characteristics, while at the same time offering the needed structural and mechanical properties. Furthermore, depending on the application, the production process has to be cost-effective and approved by local legislation.

Biofeedback

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ISBN: 9781789842579 9781789842586 Year: Pages: 122 DOI: 10.5772/intechopen.71738 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:52

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The six chapters in this volume form a timely introduction to biofeedback research. The six authors describe how objective electrophysiological data provides useful data for assessment and therapy for physical therapists, psychologists and other healthcare professionals and their clients. The first chapter, ""Biofeedback and neurofeedback in the treatment of migraine"", is written by Ph.D. student Zivoder Ivana. The second chapter by Prof. Dumitrascu looks at pelvic floor rehabilitation and is titled ""Factors predicting failure in anorectal biofeedback"". The third chapter by Dr Liao Da-Vin is titled ""Collaborative, social-networked posture training with posturing monitoring and biofeedback"". It is a useful and timely description of the role of biofeedback to support rehabilitation therapy at home and describe how objective information of physiotherapy treatments could increase the quality of service and the consistency of treatment outcomes. The fourth chapter by Prof. Silva Hugo is titled ""Bridging the clinic-home divide in muscular rehabilitation"". It also covers the role of biofeedback to support rehabilitation therapy at home. The fifth chapter is written by Ph.D. student Grin-Yatsenko Vera and is titled ""Effect of infra-low frequency neurofeedback on infra-slow-EEG-fluctuations"". The sixth and final chapter in the volume, ""Control systems of bionic limbs of the new generation and control systems with EMG signals of VR and games, toys"" by M.A. Ivaniuk Natallia goes beyond the person and shows how biofeedback can be integrated in the behavior of a bionic hand.

Body-mass Index and Health

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ISBN: 9781789850055 9781789850062 Year: Pages: 110 DOI: 10.5772/intechopen.73958 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:52

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The body mass index has an important place in weight control. Attention should be paid to the regularization of anthropometric measures and to physical activity to protect from increasing obesity that is associated with chronic noncommunicable conditions, such as diabetes mellitus, cancers and cardiovascular diseases. Also, attention should be paid to the countries that are developing. The daily intake of calories, carbohydrates, oils and proteins, fibers, vitamins and minerals and clean water is essential for all individuals, especially for children and for pregnant women.

Routledge Handbook of Genomics, Health and Society

Authors: --- --- ---
Book Series: Routledge International Handbooks ISBN: 9781138211957 Year: Pages: 316 Language: English
Publisher: Routledge
Subject: Medicine (General) --- Social Sciences
Added to DOAB on : 2018-06-22 11:01:16

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The Handbook provides an essential resource at the interface of Genomics, Health and Society, and forms a crucial research tool for both new students and established scholars across biomedicine and social sciences. Building from and extending the first Routledge Handbook of Genetics and Society, the book offers a comprehensive introduction to pivotal themes within the field, an overview of the current state of the art knowledge on genomics, science and society, and an outline of emerging areas of research. Key themes addressed include the way genomic based DNA technologies have become incorporated into diverse arenas of clinical practice and research whilst also extending beyond the clinic; the role of genomics in contemporary ‘bioeconomies’; how challenges in the governance of medical genomics can both reconfigure and stabilise regulatory processes and jurisdictional boundaries; how questions of diversity and justice are situated across different national and transnational terrains of genomic research; and how genomics informs – and is shaped by – developments in fields such as epigenetics, synthetic biology, stem cell, microbial and animal model research.

Presenting cutting edge research from leading social science scholars, the Handbook provides a unique and important contribution to the field. It brings a rich and varied cross disciplinary social science perspective that engages with both the history and contemporary context of genomics and ‘post-genomics’, and considers the now global and transnational terrain in which these developments are unfolding.

Polypeptide - New Insight into Drug Discovery and Development

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ISBN: 9781789234640 9781789234657 Year: Pages: 88 DOI: 10.5772/intechopen.68638 Language: English
Publisher: IntechOpen
Subject: Biology
Added to DOAB on : 2019-10-03 07:51:51

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Peptides are the biomolecules that consist of several amino acid chains linked through peptide bonds. This class of biomolecules is commonly found in living matter, and some of which play an imperative role in their regulation and functional activities. Peptides have been extensively applied in every aspect of human life, including cosmetics, electronics, the food industries, and pharmaceutical fields. Ultimately, peptide commercialization has become a major trend, which has been growing significantly in recent years. Viewed from the scientific perspective described above, the editor believes that the development of peptides in every aspect of human life should be accelerated. As such, this book aims to provide insight and knowledge regarding the current research that has been conducted in this field; hence, this book may encourage the reader to emphasize the importance of peptides in human life and to inspire others to identify the potency of peptides for other applications that still need further exploration. In this book, some of the compelling applications of peptides in biological and health sciences will be introduced. This book comprises an introductory chapter, along with four chapters presented by several prominent scientists who work in the field of peptide research.

Comprehensive Systems Biomedicine

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193745 Year: Pages: 113 DOI: 10.3389/978-2-88919-374-5 Language: English
Publisher: Frontiers Media SA
Subject: Genetics --- Science (General)
Added to DOAB on : 2015-11-19 16:29:12
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Systems Biomedicine is a field in perpetual development. By definition a translational discipline, it emphasizes the role of quantitative systems approaches in biomedicine and aims to offer solutions to many emerging problems characterized by levels and types of complexity and uncertainty unmet before. Many factors, including technological and societal ones, need to be considered. In particular, new technologies are providing researchers with the data deluge whose management and exploitation requires a reinvention of cross-disciplinary team efforts. The advent of “omics” and high-content imaging are examples of advances de facto establishing the necessity of systems approaches. Hypothesis-driven models and in silico validation tools in support to all the varieties of experimental applications call for a profound revision. The focus on phases like mining and assimilating the data has substantially increased so to allow for interpretable knowledge to be inferred. Notably, to be able to tackle the newly generated data dimensionality, heterogeneity and complexity, model-free and data-driven intensive applications are increasingly shaping the computational pipelines and architectures that quant specialists set aside of the high-throughput genomics, transcriptomics, proteomics platforms. As for the societal aspects, in many advanced societies health care needs now more than in the past to address the problem of managing ageing populations and their complex morbidity patterns. In parallel, there is a growing research interest on the impact that cross-disciplinary clinical, epidemiological and quantitative modelling studies can have in relation to outcomes potentially affecting the quality of life of many people. Complex systems, including those characterizing biomedicine, are assessed in both their functionality and stability, and also relatively to the capacity of generating information from diversity, variation, and complexity. Due to the combined interactions and effects, such systems embed prediction power available for instance in both target identification or marker discovery, or more generally for conducting inference about patients’ pathological states, i.e. normal versus disease, diagnostic or prognostic analysis, and preventive assessment (e.g., risk evaluation). The ultimate goal, personalized medicine, will be achieved based on the confluence of the system’s predictive power to patient-specific profiling.

Self-Reported Population Health: An International Perspective based on EQ-5D

Authors: --- ---
ISBN: 9789400775954 9789400775961 Year: Pages: 212 DOI: 10.1007/978-94-007-7596-1 Language: English
Publisher: Springer
Subject: Public Health --- Biotechnology --- Pharmacy and materia medica --- Medicine (General)
Added to DOAB on : 2014-07-25 14:27:36
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The EQ-5D instrument, as a standardized, cross-culturally validated measure of self-assessed health has a hugely important role in understanding population health within and across countries. Over the past two decades a wealth of international population health survey data have been accumulated by the EuroQol Group from research conducted in many countries across four continents. One of the success factors of the EQ-5D instruments has been the easy availability of national or international sets of EQ-5D data, as well as clear explanations and guidance for users. There is an unmet need to produce a comprehensive book that captures up-to-date and expanded information of EQ-5D self-reported health and index values. EQ-5D population norms and cross-country analyses are provided from representative national surveys of 20 countries and additional regional surveys. This book will be a must for those who believe that how people report and value health is very important.

Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models

Authors: ---
Book Series: Lecture Notes in Computational Science and Engineering ISSN: 1439-7358 ISBN: 9783319300290 9783319300306 Year: Volume: 111 Pages: 261 DOI: 10.1007/978-3-319-30030-6 Language: English
Publisher: Springer
Subject: Business and Management --- Geology --- Earth Sciences --- Computer Science --- Electrical and Nuclear Engineering --- Biotechnology --- Internal medicine --- Medicine (General) --- Therapeutics --- General and Civil Engineering
Added to DOAB on : 2017-02-15 18:39:18
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Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by changing the Markov model. These lecture notes provide an accessible introduction to the mathematical methods needed to deal with these models. They emphasize the use of numerical methods and provide sufficient details for the reader to implement the models and thereby study the effect of various drugs. Examples in the text include stochastic calcium release from internal storage systems in cells, as well as stochastic models of the transmembrane potential. Well known Markov models are studied and a systematic approach to including the effect of mutations is presented. Lastly, the book shows how to derive the optimal properties of a theoretical model of a drug for a given mutation defined in terms of a Markov model.

Umstrittene Körperteile

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Book Series: Histoire ISBN: 9783839432327 9783837632323 Year: Pages: 334 DOI: 10.14361/9783839432327 Language: German
Publisher: transcript Verlag Grant: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Subject: Medicine (General)
Added to DOAB on : 2017-03-03 11:01:22
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How did the Swiss organ donation crisis come about? Despite reforms and advertising campaigns, from the late '80s, Swiss transplant medicine began to lament an increasing mistrust in organ donation and falling donor numbers. Simon Hofmann throws light on the role of doctors, nurses, family members and donees, but also of the media, politicians and the pharmaceutical industry. In doing so, he draws out the relations between hospital practices, public debates, and fictitious narratives about organ smuggling. He tells a complex and contradictory story of modern biomedicine at the edge of life and death, which is shaped as much by economic calculations as by utopian hope and traumatic fears.

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