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A Time Travel Dialogue

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ISBN: 9781783740383 9781783740390 Year: Pages: 94 DOI: 10.11647/OBP.0043 Language: English
Publisher: Open Book Publishers
Subject: Physics (General) --- Philosophy
Added to DOAB on : 2014-09-12 12:15:27
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Abstract

Is time travel just a confusing plot device deployed by science fiction authors and Hollywood filmmakers to amaze and amuse? Or might empirical data prompt a scientific hypothesis of time travel? Structured on a fascinating dialogue involving a distinguished physicist, Dr. Rufus, a physics graduate student and a computer scientist this book probes an experimentally supported hypothesis of backwards time travel – and in so doing addresses key metaphysical issues, such as causation, identity over time and free will.The setting is the Jefferson National Laboratory during a period of five days in 2010. Dr. Rufus’s experimental search for the psi-lepton and the resulting intractable data spurs the discussion on time travel. She and her two colleagues are pushed by their observations to address the grandfather paradox and other puzzles about backwards causation, with attention also given to causal loops, multi-dimensional time, and the prospect that only the present exists. Sensible solutions to the main puzzles emerge, ultimately advancing the case for time travel really being possible.A Time Travel Dialogue addresses the possibility of time travel, approaching familiar paradoxes in a rigorous, engaging, and fun manner. It follows in the long philosophical tradition of using dialogue to present philosophical ideas and arguments, but is ground breaking in its use of the dialogue format to introduce readers to the metaphysics of time travel, and is also distinctive in its use of lab results to drive philosophical analysis. The discussion of data that might decide whether time is one-dimensional (one timeline) or multi-dimensional (branching time) is especially novel.

Mobile laser scanning based determination of railway network topology and branching direction on turnouts

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Book Series: Schriftenreihe / Institut für Mess- und Regelungstechnik, Karlsruher Institut für Technologie ISSN: 16134214 ISBN: 9783731507437 Year: Volume: 038 Pages: XII, 137 p. DOI: 10.5445/KSP/1000077900 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-28 18:37:01
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GNSS is often inaccurate and satellite signals are not always available, which results in ambiguous situations. In order to reduce their negative effects on train-borne localization, this work proposes an approach for the detection of tracks, turnouts, and branching directions solely from 2d lidar sensor measurements. The experimental evaluation shows highly correct and complete results. In summary, these detections are sufficient to reduce ambiguity problems in train-borne localization.

Organs-on-chips

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ISBN: 9783039289172 / 9783039289189 Year: Pages: 262 DOI: 10.3390/books978-3-03928-918-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2020-06-09 16:38:57
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Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices.

Keywords

microfluidics --- vascularization --- organ-on-a-chip --- vascularized tumor model --- tissue engineering --- microfluidic device --- cell culture --- organ-on-chips --- lung epithelial cell --- surfactant protein --- angiogenesis --- shear stress --- biomechanics --- vessel branching --- beating force --- bio-mechanical property --- cardiac 3D tissue --- human induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM) --- tissue engineering --- vacuum chuck --- barrier permeability --- epithelial–endothelial interface --- paracellular/transcellular transport --- organ-on-chip --- MEMS --- silicon --- PDMS --- membranes --- cell --- strain --- stress --- lattice light-sheet microscopy --- 3D cell culture system --- functional neuron imaging --- 3D cell culture --- neuronal cells --- SH-SY5Y cells --- image-based screening --- nanogrooves --- neuronal cell networks --- neuronal guidance --- drug metabolism --- biomimetic oxidation --- microfluidics --- organ-on-a-chip --- liver-on-a-chip --- liver-on-a-chip --- drug hepatotoxicity --- drug metabolism --- organoid --- 3D cell culture --- spheroid array --- high-throughput screening --- drug efficacy --- organ-on-a-chip (OOC) --- microfluidic device --- mechanical cue --- shear flow --- compression --- stretch --- strain --- syringe pump --- integrated pump --- passive delivery --- organs-on-chips --- microfluidics --- drug absorption --- fluoroelastomer --- ischemia/reperfusion injury --- thrombolysis --- organ-on-a-chip --- endothelial cell activation --- microfluidics --- microfabrication --- organ-on-a-chip --- trans-epithelial electrical resistance --- multi-culture --- n/a

Plant Genetics and Molecular Breeding

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ISBN: 9783039211753 9783039211760 Year: Pages: 628 DOI: 10.3390/books978-3-03921-176-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-08-28 11:21:27
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The development of new plant varieties is a long and tedious process involving the generation of large seedling populations for the selection of the best individuals. While the ability of breeders to generate large populations is almost unlimited, the selection of these seedlings is the main factor limiting the generation of new cultivars. Molecular studies for the development of marker-assisted selection (MAS) strategies are particularly useful when the evaluation of the character is expensive, time-consuming, or with long juvenile periods. The papers published in the Special Issue “Plant Genetics and Molecular Breeding” report highly novel results and testable new models for the integrative analysis of genetic (phenotyping and transmission of agronomic characters), physiology (flowering, ripening, organ development), genomic (DNA regions responsible for the different agronomic characters), transcriptomic (gene expression analysis of the characters), proteomic (proteins and enzymes involved in the expression of the characters), metabolomic (secondary metabolites), and epigenetic (DNA methylation and histone modifications) approaches for the development of new MAS strategies. These molecular approaches together with an increasingly accurate phenotyping will facilitate the breeding of new climate-resilient varieties resistant to abiotic and biotic stress, with suitable productivity and quality, to extend the adaptation and viability of the current varieties.

Keywords

sugarcane --- cry2A gene --- particle bombardment --- stem borer --- resistance --- NPK fertilizers --- agronomic traits --- molecular markers --- quantitative trait loci --- common wild rice --- Promoter --- Green tissue-specific expression --- light-induced --- transgenic chrysanthemum --- WRKY transcription factor --- salt stress --- gene expression --- DgWRKY2 --- Cucumis sativus L. --- RNA-Seq --- DEGs --- sucrose --- ABA --- drought stress --- Aechmea fasciata --- squamosa promoter binding protein-like --- flowering time --- plant architecture --- bromeliad --- Oryza sativa --- endosperm development --- rice quality --- WB1 --- the modified MutMap method --- abiotic stress --- Cicer arietinum --- candidate genes --- genetics --- heat-stress --- molecular breeding --- metallothionein --- Brassica --- Brassica napus --- As3+ stress --- broccoli --- cytoplasmic male sterile --- bud abortion --- gene expression --- transcriptome --- RNA-Seq --- sesame --- genome-wide association study --- yield --- QTL --- candidate gene --- cabbage --- yellow-green-leaf mutant --- recombination-suppressed region --- bulk segregant RNA-seq --- differentially expressed genes --- marker–trait association --- haplotype block --- genes --- root traits --- D-genome --- genotyping-by-sequencing --- single nucleotide polymorphism --- durum wheat --- bread wheat --- complex traits --- Brassica oleracea --- Ogura-CMS --- iTRAQ --- transcriptome --- pollen development --- rice --- OsCDPK1 --- seed development, starch biosynthesis --- endosperm appearance --- Chimonanthus praecox --- nectary --- floral scent --- gene expression --- Prunus --- flowering --- bisulfite sequencing --- genomics --- epigenetics --- breeding --- AP2/ERF genes --- Bryum argenteum --- transcriptome --- gene expression --- stress tolerance --- SmJMT --- transgenic --- Salvia miltiorrhiza --- overexpression --- transcriptome --- phenolic acids --- Idesia polycarpa var --- glycine --- FAD2 --- linoleic acid --- oleic acid --- anther wall --- tapetum --- pollen accumulation --- OsGPAT3 --- rice --- cytoplasmic male sterility (CMS) --- phytohormones --- differentially expressed genes --- pollen development --- Brassica napus --- Rosa rugosa --- RrGT2 gene --- Clone --- VIGS --- Overexpression --- Tobacco --- Flower color --- Anthocyanin --- sugarcane --- WRKY --- subcellular localization --- gene expression pattern --- protein-protein interaction --- transient overexpression --- soybean --- branching --- genome-wide association study (GWAS) --- near-isogenic line (NIL) --- BRANCHED1 (BRC1) --- TCP transcription factor --- Zea mays L. --- MADS transcription factor --- ZmES22 --- starch --- flowering time --- gene-by-gene interaction --- Hd1 --- Ghd7 --- rice --- yield trait --- Oryza sativa L. --- leaf shape --- yield trait --- molecular breeding --- hybrid rice --- nutrient use efficiency --- quantitative trait loci (QTLs), molecular markers --- agronomic efficiency --- partial factor productivity --- P. suffruticosa --- R2R3-MYB --- overexpression --- anthocyanin --- transcriptional regulation --- ethylene-responsive factor --- Actinidia deliciosa --- AdRAP2.3 --- gene expression --- waterlogging stress --- regulation --- Chrysanthemum morifolium --- WUS --- CYC2 --- gynomonoecy --- reproductive organ --- flower symmetry --- Hs1pro-1 --- cZR3 --- gene pyramiding --- Heterodera schachtii --- resistance --- tomato --- Elongated Internode (EI) --- QTL --- GA2ox7 --- n/a

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