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Medical Innovation: Science, technology and practice

Authors: --- --- ---
Book Series: Routledge International Studies in Health Economics ISBN: 9781138860346 Year: Pages: 186 pages | 26 B/W I Language: English
Publisher: Routledge Grant: Wellcome Trust - 097665
Subject: Medicine (General) --- Business and Management --- Economics
Added to DOAB on : 2016-09-10 11:01:16
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Abstract

This book brings together a collection of empirical case studies featuring a wide spectrum of medical innovation. While there is no unique pathway to successful medical innovation, recurring and distinctive features can be observed across different areas of clinical practice. This book examines why medical practice develops so unevenly across and within areas of disease, and how this relates to the underlying conditions of innovation across areas of practice. The contributions contained in this volume adopt a dynamic perspective on medical innovation based on the notion that scientific understanding, technology and clinical practice co-evolve along the co-ordinated search for solutions to medical problems. The chapters follow an historical approach to emphasise that the advancement of medical know-how is a contested, nuanced process, and that it involves a variety of knowledge bases whose evolutionary paths are rooted in the contexts in which they emerge.

This book will be of interest to researchers and practitioners concerned with medical innovation, management studies and the economics of innovation.

Chapter 5 of this book is freely available as a downloadable Open Access PDF at www.tandfebooks.com/openaccess. It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license.

Technological Accretion in Diagnostics (Book chapter)

Book title: Medical Innovation: Science, technology and practice

Authors: --- --- ---
Book Series: Routledge International Studies in Health Economics ISBN: 9781138860346 Year: Pages: 186 pages | 26 B/W I Language: English
Publisher: Routledge Grant: Wellcome Trust - 097665
Subject: Medicine (General) --- Business and Management --- Economics
Added to DOAB on : 2018-06-22 11:01:02
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Abstract

This book brings together a collection of empirical case studies featuring a wide spectrum of medical innovation. While there is no unique pathway to successful medical innovation, recurring and distinctive features can be observed across different areas of clinical practice. This book examines why medical practice develops so unevenly across and within areas of disease, and how this relates to the underlying conditions of innovation across areas of practice. The contributions contained in this volume adopt a dynamic perspective on medical innovation based on the notion that scientific understanding, technology and clinical practice co-evolve along the co-ordinated search for solutions to medical problems. The chapters follow an historical approach to emphasise that the advancement of medical know-how is a contested, nuanced process, and that it involves a variety of knowledge bases whose evolutionary paths are rooted in the contexts in which they emerge.

This book will be of interest to researchers and practitioners concerned with medical innovation, management studies and the economics of innovation.

Chapter 5 of this book is freely available as a downloadable Open Access PDF at www.tandfebooks.com/openaccess. It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license.

Towards translating research to clinical practice: Novel Strategies for Discovery and Validation of Biomarkers for Brain Injury

Authors: --- --- --- --- et al.
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193912 Year: Pages: 178 DOI: 10.3389/978-2-88919-391-2 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Neurology
Added to DOAB on : 2015-12-03 13:02:24
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Traumatic brain injury (TBI) is a major cause of death and disability and one of the greatest unmet needs in medicine and public health. TBI not only has devastating effects on patients and their relatives but results in huge direct and indirect costs to society. Although guidelines for the management of patients have been developed and more than 200 clinical trials have been conducted, they have resulted in few improvements in clinical outcomes and no effective therapies approved for TBI. It is now apparent that the heterogeneity of clinical TBI is underlain by molecular phenotypes more complex and interactive than initially conceived and current approaches to the characterization, management and outcome prediction of TBI are antiquated, unidimensional and inadequate to capture the interindividual pathophysiological heterogeneity. Recent advances in proteomics and biomarker development provide unparalleled opportunities for unraveling substantial injury-specific and patient-specific variability and refining disease characterization. The identification of novel, sensitive, objective tools, referred to as biomarkers, can revolutionize pathophysiological insights, enable targeted therapies and personalized approaches to clinical management. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. Finally, suggestions are provided for the way forward, with an emphasis on need for a multidimensional approach that integrate a panel of pathobiologically diverse biomarkers with clinical variables and imaging-based assessments to improve diagnosis and classification of TBI and to develop best clinical practice guidelines.

Integrating Religion and Spirituality into Clinical Practice

Authors: ---
ISBN: 9783038429302 9783038429296 Year: Pages: X, 224 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2018-05-18 07:58:29
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The present Special Issue Book is a collection of scientific articles from the European Conferences of Religion, Spirituality and Health in 2014 (Malta) and 2016 (Gdansk). The overall theme is “Integrating Religion and Spirituality into Clinical Practice”. Studies are grouped under four main topics: Religion and Spirituality in Patient Care, Spirituality in Physical and Mental Disease, Health Care Professionals and Spirituality, and Faith-Based Services and Programs in Health Care. The chapters illustrate the broad range of topics presented.

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