Search results: Found 6

Listing 1 - 6 of 6
Sort by
Colorectal Cancer - From Pathogenesis to Treatment

Author:
ISBN: 9789535125440 9789535125457 9789535141846 Year: Pages: 440 DOI: 10.5772/61359 Language: English
Publisher: IntechOpen
Subject: Surgery
Added to DOAB on : 2019-10-03 07:51:49

Loading...
Export citation

Choose an application

Abstract

Colorectal cancer (CRC) is a major health problem because it represents around 10% of all cancers and achieves a worldwide estimate of 1.4 million newly diagnosed cases annually, resulting in approximately 700,000 deaths. Approximately 19-31% of patients present liver metastases. At diagnosis, a further 23-38% will develop extra-hepatic disease. Over the past decade, the widespread use of modern chemotherapeutic and biological agents, combined with laparoscopic surgical techniques, has improved the prognosis of metastatic CRC. A better understanding of the biology of the tumor, along with high efficiency of diagnostic and therapeutic methods, as well as the spread of screening programs, will improve the survival of the CRC patients in the near future.

Colorectal Cancer - Diagnosis, Screening and Management

Author:
ISBN: 9781789231007 9781789231014 Year: Pages: 128 DOI: 10.5772/intechopen.68430 Language: English
Publisher: IntechOpen
Subject: Surgery
Added to DOAB on : 2019-10-03 07:51:51

Loading...
Export citation

Choose an application

Abstract

With international experts sharing their experience and knowledge on these different aspects in the management of colorectal cancer, this book has this opportunity to offer all physicians treating colorectal cancer, as well as researchers, updated information concerning the biology, diagnosis, screening, and treatment of colorectal carcinoma. This book provides a detailed evaluation of diagnostic modalities, in-depth analysis of screening for colorectal cancer, recent advances in treatment, and principles and trends in the management of colorectal cancer. This updated knowledge will be an interesting and informative read for any clinician involved in the management of patients with colorectal cancer. In addition, readers such as related physicians, researchers, and colorectal cancer patients are potential beneficiaries of this book.

Proctological Diseases in Surgical Practice

Author:
ISBN: 9781789236347 9781789236354 Year: Pages: 170 DOI: 10.5772/intechopen.71454 Language: English
Publisher: IntechOpen
Subject: Surgery
Added to DOAB on : 2019-10-03 07:51:51

Loading...
Export citation

Choose an application

Abstract

The prevalence of anorectal disorders in the general population is probably much higher than that seen in clinical practice. Anorectal diseases have for a long time been considered of little interest, with their treatment considered of little prestige despite the social impact they cause to patients. Proctology was initiated late and developed slowly over the years. However, in the last 20 years, a renewed interest has begun, and today, we can say that proctology is a specialized branch of general surgery. This book ""Proctological Diseases in Surgical Practice"" provides a practical introduction to proctology, with a particular attention to the topics that have not yet been investigated. This book may be useful for the general physician as well as for the specialist.

Towards a molecular classification of colorectal cancer

Author:
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195671 Year: Pages: 62 DOI: 10.3389/978-2-88919-567-1 Language: English
Publisher: Frontiers Media SA
Subject: Oncology --- Medicine (General)
Added to DOAB on : 2016-02-05 17:24:33
License:

Loading...
Export citation

Choose an application

Abstract

In 2007, Jeremy Jass proposed a molecular classification of colorectal cancer including KRAS, BRAF, Mismatch Repair, CIMP and MGMT Status. Since then, many prognostic and predictive studies have been published on this topic, mainly focusing on one single molecular marker. The aim of the e-book is to summarize the knowledge in 2014 from a multidisciplinary point of view that can potentially be used as a manual by CRC researchers in every field.

MicroRNA as Biomarkers in Cancer Diagnostics and Therapy

Author:
ISBN: 9783039212491 / 9783039212507 Year: Pages: 166 DOI: 10.3390/books978-3-03921-250-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Microbiology
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to represent unique microRNA genes in humans, with an increasing number of mechanistic roles identified in developmental, physiological, and pathological processes. Thus, dysregulation of a few key microRNAs can have a profound global effect on the gene expression and molecular programs of a cell. This great potential for clinical intervention has captured the interest and imagination of researchers in many fields. However, very few fields have been as prolific as the field of cancer research. This Special Issue provides but a glimpse of the large body of literature of microRNA biology in cancer research, containing 4 original research studies and 4 review articles that focus on specific hematologic or solid tumors in disease. Collectively, these articles highlight state-of-the-art approaches and methodologies for microRNA detection in tissue, blood, and other body fluids in a range of biomarkers applications, from early cancer detection to prognosis and treatment response. The articles also address some of the challenges regarding clinical implementation.

Wine and Vine Components and Health

Authors: ---
ISBN: 9783039211388 / 9783039211395 Year: Pages: 154 DOI: 10.3390/books978-3-03921-139-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

While there is a tremendous literature on the topic of wine and health ranging back to the days of Hippocrates, it is considered that there is an unlimited variety of wine, allowing for the association of senses, nutrition, and hedonism. The history of vine and wine has lasted for at least 7000 years. Vitis represent adaptable plants, and thanks to the large variety of strains, wine is an alchemical mix with unique properties, a rich and original composition in terms of polyphenols, and well known antioxidants. This explains why wine and health are closely linked to nutrition.

Listing 1 - 6 of 6
Sort by
Narrow your search