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Computational Modelling of the Steps Involved in Photodynamic Therapy (Book chapter)

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ISBN: 9789535104469 Year: DOI: 10.5772/37654 Language: English
Publisher: IntechOpen Grant: FP7 Ideas: European Research Council - 258990
Subject: Science (General)
Added to DOAB on : 2019-01-17 11:47:59
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Photodynamic therapy (PDT) is a branch of phototherapy that has seen a surge of interest in the last few decades, due to its potential in the treatment of various cancers, infections and&#xD;&#xD;heart disease.(Bonnett, 2000) This chapter aims to give an overview of the various&#xD;&#xD;photochemical steps involved in PDT as a cancer therapy, and in particular the challenges&#xD;&#xD;and insight gained from their theoretical description. After a brief review of PDT in general,&#xD;&#xD;in a biological and chemical context, the photochemical steps involved will be discussed,&#xD;&#xD;detailing the computational techniques required to model these chemical pathways&#xD;&#xD;theoretically. We will detail the methodologies that can currently be applied, as well as their&#xD;&#xD;limitations of use at present, and areas requiring further development.

Biocomputing 2016:Proceedings of the Pacific Symposium

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ISBN: 9789814749411 Year: Pages: 604 DOI: 10.1142/9930 Language: English
Publisher: World Scientific Publishing Co.
Subject: Biology
Added to DOAB on : 2016-01-19 03:27:59
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The Pacific Symposium on Biocomputing (PSB) 2016 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2016 will be held on January 4 – 8, 2016 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2016 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's "hot topics." In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.Contents:Cancer Panomics: Computational Methods and Infrastructure for Integrative Analysis of Cancer High-Throughput "Omics" DataComputational Approaches to Drug Repurposing and PharmacologyDetecting and Characterizing Pleiotropy: New Methods for Uncovering the Connection Between the Complexity of Genomic Architecture and Multiple PhenotypesPersonalized Medicine: From Genotypes and Molecular Phenotypes Towards TherapyText and Data Mining for Biomedical DiscoveryReadership: Academia and industry in the fields of biocomputing, bioinformatics and computational biology.

Biocomputing 2015:Proceedings of the Pacific Symposium

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ISBN: 9789814644730 Year: Pages: 516 DOI: 10.1142/9455 Language: English
Publisher: World Scientific Publishing Co.
Subject: Biology
Added to DOAB on : 2016-01-19 03:42:23
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The Pacific Symposium on Biocomputing (PSB) 2015 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2015 will be held from January 4 – 8, 2015 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2015 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.Contents:Cancer Panomics: Computational Methods and Infrastructure for Integrative Analysis of Cancer High-Throughput "OMICS" DataCancer Pathways: Automatic Extraction, Representation, and Reasoning in the "Big Data" ERACharacterizing the Importance of Environmental Exposures, Interactions Between the Environment and Genetic Architecture, and Genetic Interactions: New Methods for Understanding the Etiology of Complex Traits and DiseaseCrowdsourcing and Mining Crowd DataPersonalized Medicine: From Genotypes, Molecular Phenotypes and the Quantified Self, Towards Improved MedicineReadership: Academia and industry in the fields of biocomputing, bioinformatics and computational biology.

Biocomputing 2014:Proceedings of the Pacific Symposium

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ISBN: 9789814583220 Year: Pages: 436 DOI: 10.1142/9078 Language: English
Publisher: World Scientific Publishing Co.
Subject: Biology
Added to DOAB on : 2016-01-19 03:46:40
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The Pacific Symposium on Biocomputing (PSB) 2014 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2014 will be held from January 3 – 7, 2014 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2014 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.Contents:Cancer Panomics: Computational Methods and Infrastructure for Integrative Analysis of Cancer High-Throughput “Omics” DataComputational Approaches to Drug Repurposing and PharmacologyDetecting and Characterizing Pleiotropy: New Methods for Uncovering the Connection Between the Complexity of Genomic Architecture and Multiple PhenotypesPersonalized Medicine: From Genotypes and Molecular Phenotypes Towards TherapyText and Data Mining for Biomedical DiscoveryWorkshopsReadership: Academia and industry in the fields of biocomputing, bioinformatics and computational biology.

Biocomputing 2017:Proceedings of the Pacific Symposium

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ISBN: 9789813207813 Year: Pages: 668 DOI: 10.1142/10388 Language: English
Publisher: World Scientific Publishing Co.
Subject: Biology
Added to DOAB on : 2016-12-02 03:01:48
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The Pacific Symposium on Biocomputing (PSB) 2017 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2017 will be held on January 4 – 8, 2017 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2017 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's "hot topics." In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Biocomputing 2018:Proceedings of the Pacific Symposium

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ISBN: 9789813235533 Year: Pages: 500 DOI: 10.1142/10864 Language: English
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2017-11-20 08:35:10
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The Pacific Symposium on Biocomputing (PSB) 2018 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2018 will be held on January 3 – 7, 2018 in Kohala Coast, Hawaii.PSB 2018 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's "hot topics." In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Biocomputing 2019:Proceedings of the Pacific Symposium:Pacific Symposium on Biocomputing 2019

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ISBN: 9789813279827 Year: Pages: 472 DOI: 10.1142/11263 Language: ENG
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-01-23 03:26:21
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The Pacific Symposium on Biocomputing (PSB) 2019 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2019 will be held on January 3 – 7, 2019 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2019 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's "hot topics." In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Genome Informatics 2009:Genome Informatics Series Vol. 23

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Book Series: Genome Informatics Series ISBN: 9781848165632 Year: Pages: 240 DOI: 10.1142/p715 Language: ENGLISH
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-07-04 04:35:35

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This volume contains papers presented at the 20th International Conference on Genome Informatics (GIW 2009) held at the Pacifico Yokohama, Japan from December 14 to 16, 2009. The GIW Series provides an international forum for the presentation and discussion of original research papers on all aspects of bioinformatics, computational biology and systems biology. Its scope includes biological sequence analysis, protein structure prediction, genetic regulatory networks, bioinformatic algorithms, comparative genomics, and biomolecular data integration and analysis. Boasting a history of 20 years, GIW is the longest-running international bioinformatics conference.A total of 18 contributed papers were selected for presentation at GIW 2009 and for inclusion in this book. In addition, this book contains abstracts from the five invited speakers: Sean Eddy (HHMI's Janelia Farm, USA), Minoru Kanehisa (Kyoto University, Japan), Sang Yup Lee (KAIST, Korea), Hideyuki Okano (Keio University, Japan) and Mark Ragan (University of Queensland, Australia).

Biocomputing 2013:Proceedings of the Pacific Symposium

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ISBN: 9789814447973 Year: Pages: 472 DOI: 10.1142/8694 Language: ENGLISH
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-07-04 04:52:48

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The Pacific Symposium on Biocomputing (PSB) 2013 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2013 will be held on January 3 – 7, 2013 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2013 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Biocomputing 2012:Proceedings of the Pacific Symposium

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ISBN: 9789814366496 Year: Pages: 452 DOI: 10.1142/8254 Language: ENGLISH
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-07-04 05:19:11

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The Pacific Symposium on Biocomputing (PSB) 2012 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in the problems of biological significance. Presentations are rigorously peer-reviewed and are published in an archival proceedings volume. PSB 2012 will be held on January 3 – 7, 2012 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2012 will bring together top researchers from the US, the Asian Pacific nations, and countries around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods as applied to biological problems, with emphasis on the applications in the data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

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