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Mathematics for Healthcare

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889455775 Year: Pages: 284 DOI: 10.3389/978-2-88945-577-5 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Physiology
Added to DOAB on : 2019-01-23 14:53:43
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In 1996, and with extraordinary prescience, Panfilov and Holden had highlighted in their seminal book 'Computational Biology of the Heart' that biology was, potentially, the most mathematical of all sciences. Fast-forward 20 years and we have seen an explotion of applications of mathematics in not only biology, but healthcare that has already produced significant breakthroughs not imaginable more than 20 years ago. Great strides have been made in explaining through quantitative methods the underlying mechanisms of human disease, not without considerable ingenuity and effort. Biological mechanisms are bewildering: complex, ever evolving, multi-scale, variable, difficult to fully access and understand. This poses immense challenges to the computational physiology community that, nevertheless, has developed an impressive arsenal of tools and methods in a vertiginous race to combat disease with the tall order of improving human healthcare. Mechanistic models are now contending with the advent of machine learning in healthcare and the hope is that both approaches will be used synergistically since the complexity of human patophysiology and the difficulty of acquiring human datasets will require both, deductive and inductive methods. This Research Topic presents work that is currently at the frontier in computational physiology with a striking range of applications, from diabetes to graft failure and using a multitude of mathematical tools. This collection of articles represents a snapshot in a field that is moving a dizzying speed, bringing understanding of fundamental mechanism and solutions to healthcare problems experienced by healthcare systems all over the world.

Non-Equilibrium Social Science and Policy: Introduction and Essays on New and Changing Paradigms in Socio-Economic Thinking

Authors: --- --- --- --- et al.
Book Series: Understanding Complex Systems ISSN: 1860-0832 ISBN: 9783319424224 9783319424248 Year: Pages: 232 DOI: 10.1007/978-3-319-42424-8 Language: English
Publisher: Springer
Subject: Astronomy (General) --- Physics (General) --- Business and Management --- Electrical and Nuclear Engineering
Added to DOAB on : 2017-03-13 12:35:53
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The overall aim of this book, an outcome of the European FP7 FET Open NESS project, is to contribute to the ongoing effort to put the quantitative social sciences on a proper footing for the 21st century. A key focus is economics, and its implications on policy making, where the still dominant traditional approach increasingly struggles to capture the economic realities we observe in the world today - with vested interests getting too often in the way of real advances.Insights into behavioral economics and modern computing techniques have made possible both the integration of larger information sets and the exploration of disequilibrium behavior. The domain-based chapters of this work illustrate how economic theory is the only branch of social sciences which still holds to its old paradigm of an equilibrium science - an assumption that has already been relaxed in all related fields of research in the light of recent advances in complex and dynamical systems theory and related data mining.The other chapters give various takes on policy and decision making in this context. Written in nontechnical style throughout, with a mix of tutorial and essay-like contributions, this book will benefit all researchers, scientists, professionals and practitioners interested in learning about the 'thinking in complexity' to understand how socio-economic systems really work.

Structural Control of Mineral Deposits. Theory and Reality

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ISBN: 9783038977841 / 9783038977858 Year: Pages: 256 DOI: 10.3390/books978-3-03897-785-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General)
Added to DOAB on : 2019-06-26 10:09:00
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""Structural Control"" remains a crucial point that frequently lacks in any scientific and/or economic analysis of ore deposits, whatever their type and class. The case of lode deposits is exemplary, although also other deposits, like breccia pipe, stockwerk, massive sulphides, skarn, etc., can, surprisingly, be concerned. Several concepts like the gold-bearing shear zone have not proven valid during the last few decades in terms of our understanding of gold deposit and have been totally abandoned. Additionally, the relationships between magmatism, regional tectonic context, and mineralization remain uncertain and have been debated in several recent publications. This demonstrates that this issue is still relevant, and its solution may help in the distinction between intrusion-related and orogenic deposits. In this Special Issue, we particularly invite any case study of mineral deposits, in which it has been demonstrated that structural geology may have a significant role in the establishment of the deposit model of formation and/or on exploration and exploitation programs. Examples in which the structural model diverges from those described in the classical literature are particularly welcomed, including studies in which relationships with magmatism can be suspected and/or demonstrated. Indeed, all cases that illustrate concepts that differ from the classic ones and from theoretical models may represent significant contributions to this volume.

Assimilation of Remote Sensing Data into Earth System Models

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ISBN: 9783039216406 / 9783039216413 Year: Pages: 236 DOI: 10.3390/books978-3-03921-641-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General)
Added to DOAB on : 2019-12-09 11:49:16
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In the Earth sciences, a transition is currently occurring in multiple fields towards an integrated Earth system approach, with applications including numerical weather prediction, hydrological forecasting, climate impact studies, ocean dynamics estimation and monitoring, and carbon cycle monitoring. These approaches rely on coupled modeling techniques using Earth system models that account for an increased level of complexity of the processes and interactions between atmosphere, ocean, sea ice, and terrestrial surfaces. A crucial component of Earth system approaches is the development of coupled data assimilation of satellite observations to ensure consistent initialization at the interface between the different subsystems. Going towards strongly coupled data assimilation involving all Earth system components is a subject of active research. A lot of progress is being made in the ocean–atmosphere domain, but also over land. As atmospheric models now tend to address subkilometric scales, assimilating high spatial resolution satellite data in the land surface models used in atmospheric models is critical. This evolution is also challenging for hydrological modeling. This book gathers papers reporting research on various aspects of coupled data assimilation in Earth system models. It includes contributions presenting recent progress in ocean–atmosphere, land–atmosphere, and soil–vegetation data assimilation.

Energy Performance and Indoor Climate Analysis in Buildings

Authors: --- ---
ISBN: 9783039213795 / 9783039213801 Year: Pages: 374 DOI: 10.3390/books978-3-03921-380-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:16
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HVAC systems, load shifting, indoor climate, and energy and ventilation performance analyses are the key topics when improving energy performance in new and renovated buildings. This development has been boosted by the recently established nearly zero energy building requirements that will soon be in use in all EU Member States, as well as similar long-term zero energy building targets in Japan, the US, and other countries. The research covered in this Special Issue provides evidence of how new technical solutions have worked, in practice, in new or renovated buildings, and also discusses problems and how solutions should be further developed. Another focus is on the more detailed calculation methods needed for the correct design and sizing of dedicated systems, and for accurate quantification of energy savings. Occupant behavior and building operation is also examined, in order to avoid common performance gaps between calculated and measured performance. These topics demonstrate the challenge of high performance buildings as, in the end, comfortable buildings with good indoor climate which are easy and cheap to operate and maintain are expected by end customers. Ventilation performance, heating and cooling, sizing, energy predictions and optimization, load shifting, and field studies are some of the key topics in this Special Issue, contributing to the future of high performance buildings with reliable operation.

Keywords

Jaya algorithm --- smart grid --- optimal energy management --- demand response --- demand side management --- indoor temperature after renovation --- electricity use --- DHW energy use --- user behavior --- standard use --- energy performance modeling --- gray box --- satellite-based solar radiation data --- meteorological reanalysis data --- ISO 52016-1 --- energy efficiency --- HVAC systems --- chiller plants --- chiller performance --- COP --- data-driven analysis --- energy --- building --- ventilation --- cooling --- outdoor air --- air jet --- personalized ventilation --- skin temperature --- CFD --- thermal analysis --- corner impinging jet --- mixing ventilation --- displacement ventilation --- tracer gas --- air exchange effectiveness --- local air change effectiveness --- draught rate --- Monte Carlo method --- ISO 7730 --- TRNSYS --- greenhouse --- indoor temperature uniformity --- multiple sensor nodes --- qualitative control --- corner impinging jet --- corner mixing ventilation --- hybrid displacement device --- heating mode --- thermal comfort --- air exchange effectiveness --- local air change effectiveness --- draught rate, --- downdraught --- smart buildings --- smart readiness indicator --- energy efficiency --- energy performance of buildings directive --- energy flexibility --- load shifting --- demand response --- building energy simulation --- occupant behavior --- energy performance --- indoor climate --- retirement home --- user input data --- condenser evaporative precooling --- rooftop air conditioners --- building energy modelling --- control strategy --- ground source heat pump --- heating power --- sizing --- DHW heating --- space heating --- alternate operation --- daylight --- existing buildings --- daylight factor --- daylight simulations --- daylight survey --- energy efficiency --- student dormitories --- Indoor Environmental Quality (IEQ), Pro-GET-onE H2020 --- in situ measurements --- monitoring measurements --- energy signature --- indoor air quality --- stratification --- basketball hall --- CFD --- field measurement --- single room ventilation unit --- building pressure condition --- stack effect --- wind pressure --- ventilation renovation --- decentralized ventilation unit

Structural Prognostics and Health Management in Power & Energy Systems

Authors: --- --- --- --- et al.
ISBN: 9783039217663 / 9783039217670 Year: Pages: 218 DOI: 10.3390/books978-3-03921-767-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Philosophy
Added to DOAB on : 2020-01-30 16:39:46
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The idea of preparing an Energies Special Issue on “Structural Prognostics and Health Management in Power & Energy Systems” is to compile information on the recent advances in structural prognostics and health management (SPHM). Continued improvements on SPHM have been made possible through advanced signature analysis, performance degradation assessment, as well as accurate modeling of failure mechanisms by introducing advanced mathematical approaches/tools. Through combining deterministic and probabilistic modeling techniques, research on SPHM can provide assurance for new structures at a design stage and ensure construction integrity at a fabrication phase. Specifically, power and energy system failures occur under multiple sources of uncertainty/variability resulting from load variations in usage, material properties, geometry variations within tolerances, and other uncontrolled variations. Thus, advanced methods and applications for theoretical, numerical, and experimental contributions that address these issues on SPHM are desired and expected, which attempt to prevent overdesign and unnecessary inspection and provide tools to enable a balance between safety and economy to be achieved. This Special Issue has attracted submissions from China, USA, Portugal, and Italy. A total of 26 submissions were received and 11 articles finally published.

Keywords

prognostics --- residual useful life --- similarity-based approach --- supporting vector machine (SVM) --- reliability --- non-probabilistic reliability index --- sensitivity analysis --- techno-economic assessments --- life cycle cost --- vibration transmission mechanism --- underground powerhouse --- lateral-river vibration --- low frequency tail fluctuation --- rotation of hydraulic generator --- vertical axis wind turbine --- structural health monitoring --- operational modal analysis --- stochastic subspace identification --- vibration test --- offshore structures --- oil and gas platforms --- offshore wind turbines --- retrofitting activities --- renewable energy --- dynamic analysis --- wind and wave analysis --- dynamic analysis of the structure --- wave–structure interaction (WSI) --- probabilistic analyses of stochastic processes and frequency --- data-driven --- machine learning --- deep learning --- DNN --- prognostic and Health Management --- lithium-ion battery --- wind turbines --- health monitoring --- fault detection --- optimized deep belief networks --- supervisory control and data acquisition system --- multioperation condition --- wind turbine blade --- full-scale static test --- neural networks --- strain prediction --- dynamic fuzzy reliability analysis --- extremum surface response method --- weighted regression --- turbine blisk --- fuzzy safety criterion --- lithium-ion battery --- remaining useful life --- regeneration phenomenon --- wavelet decomposition --- NAR neural network --- empirical mode decomposition --- analysis mode decomposition --- analysis-empirical mode decomposition --- mode mixing --- sifting stop criterion

Control and Nonlinear Dynamics on Energy Conversion Systems

Authors: ---
ISBN: 9783039211104 / 9783039211111 Year: Pages: 438 DOI: 10.3390/books978-3-03921-111-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-08-28 11:21:27
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The ever-increasing need for higher efficiency, smaller size, and lower cost make the analysis, understanding, and design of energy conversion systems extremely important, interesting, and even imperative. One of the most neglected features in the study of such systems is the effect of the inherent nonlinearities on the stability of the system. Due to these nonlinearities, these devices may exhibit undesirable and complex dynamics, which are the focus of many researchers. Even though a lot of research has taken place in this area during the last 20 years, it is still an active research topic for mainstream power engineers. This research has demonstrated that these systems can become unstable with a direct result in increased losses, extra subharmonics, and even uncontrollability/unobservability. The detailed study of these systems can help in the design of smaller, lighter, and less expensive converters that are particularly important in emerging areas of research like electric vehicles, smart grids, renewable energy sources, and others. The aim of this Special Issue is to cover control and nonlinear aspects of instabilities in different energy conversion systems: theoretical, analysis modelling, and practical solutions for such emerging applications. In this Special Issue, we present novel research works in different areas of the control and nonlinear dynamics of energy conversion systems.

Keywords

data-driven --- prediction --- neural network --- air-handling unit (AHU) --- supply air temperature --- pulverizing system --- soft sensor --- inferential control --- moving horizon estimation --- multi-model predictive control --- micro-grid --- droop control --- virtual impedance --- harmonic suppression --- power quality --- combined heat and power unit --- two-stage bypass --- dynamic model --- coordinated control system --- predictive control --- decoupling control --- power conversion --- model–plant mismatches --- disturbance observer --- performance recovery --- offset-free --- electrical machine --- electromagnetic vibration --- multiphysics --- rotor dynamics --- air gap eccentricity --- calculation method --- magnetic saturation --- corrugated pipe --- whistling noise --- Helmholtz number --- excited modes --- switched reluctance generator --- capacitance current pulse train control --- voltage ripple --- capacitance current --- feedback coefficient --- distributed architecture --- maximum power point tracking --- sliding mode control --- overvoltage --- permanent magnet synchronous motor (PMSM) --- single artificial neuron goal representation heuristic dynamic programming (SAN-GrHDP) --- single artificial neuron (SAN) --- reinforcement learning (RL) --- goal representation heuristic dynamic programming (GrHDP) --- adaptive dynamic programming (ADP) --- sliding mode observer (SMO) --- permanent magnet synchronous motor (PMSM) --- extended back electromotive force (EEMF) --- position sensorless --- bridgeless converter --- discontinuous conduction mode (DCM) --- high step-up voltage gain --- power factor correction (PFC) --- space mechanism --- multi-clearance --- nonlinear dynamic model --- planetary gears --- vibration characteristics --- new step-up converter --- ultrahigh voltage conversion ratio --- small-signal model --- average-current mode control --- slope compensation --- monodromy matrix --- current mode control --- boost-flyback converter --- explosion-magnetic generator --- plasma accelerator --- current-pulse formation --- DC-DC buck converter --- contraction analysis --- global stability --- matrix norm --- DC micro grid --- efficiency optimization --- variable bus voltage MG --- variable switching frequency DC-DC converters --- centralized vs. decentralized control --- local vs. global optimization --- buck converter --- DC motor --- bifurcations in control parameter --- sliding control --- zero average dynamics --- fixed-point inducting control --- DC-DC converters --- quadratic boost --- maximum power point tracking (MPPT) --- nonlinear dynamics --- subharmonic oscillations --- photovoltaic (PV) --- steel catenary riser --- rigid body rotation --- wave --- the load of suspension point in the z direction --- Cable3D

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