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Simulation, Aufbau und Charakterisierung von autostereoskopischen Display-Systemen im Fahrzeugbereich

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Book Series: Spektrum der Lichttechnik / Karlsruher Institut für Technologie (KIT), Lichttechnisches Institut ISSN: 21951152 ISBN: 9783731506171 Year: Volume: 13 Pages: IV, 264 p. DOI: 10.5445/KSP/1000063916 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:02:00
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In order to extend the functionality of head-up displays as an ergonomic driver assistance system an autostereoscopic approach is investigated. Thereby, depth perception is gained by the fusion of two separated images. Adapted simulation methods are developed and used as a basis for the optical design process. Different technological concepts are developed, analyzed in simulation, as well as realized and characterized in prototypical setups.

Effiziente und optimierte Darstellungen von Informationen auf Grafikanzeigen im Fahrzeug: Situationsadaptive Bildaufbereitungsalgorithmen und intelligente Backlightkonzepte

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Book Series: Spektrum der Lichttechnik / Karlsruher Institut für Technologie (KIT), Lichttechnisches Institut ISSN: 21951152 ISBN: 9783866449619 Year: Volume: 2 Pages: VIII, 137 p. DOI: 10.5445/KSP/1000031973 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:02:02
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Inhalte für Displays werden für relativ dunkle Umgebungslichtbedingungen (0.5-500lx) optimiert. Unsere Wahrnehmung dieser Inhalte ist im Automobil durch die wechselnden Lichtbedingungen (0.5-100klx) starken Variationen unterworfen. Ziel dieser Arbeit ist es durch intelligente Steuerung der Displayhelligkeit, Modifizierung der dargestellten Inhalte und Optimierung der Hinterleuchtungstechnik die darzustellenden Inhalte dynamisch in Echtzeit optimal an die visuelle Wahrnehmung anzupassen.

Multimodale Interaktion in Multi-Display-Umgebungen

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Book Series: Karlsruher Schriften zur Anthropomatik / Lehrstuhl für Interaktive Echtzeitsysteme, Karlsruher Institut für Technologie ; Fraunhofer-Inst. für Optronik, Systemtechnik und Bildauswertung IOSB Karlsruhe ISSN: 18636489 ISBN: 9783866447608 Year: Volume: 9 Pages: XVII, 240 p. DOI: 10.5445/KSP/1000024819 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Computer Science
Added to DOAB on : 2019-07-30 20:02:00
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Interaktive Umgebungen entwickeln sich mehr und mehr weg von Einzelarbeitsplätzen, hin zu Multi-Display-/Multi-User-Umgebungen. Diese stellen neue Anforderungen an Eingabegeräte und Interaktionstechniken. Im Rahmen dieser Arbeit werden neue Ansätze zur Interaktion auf Basis von Handgesten und Blick als neuartige Eingabemodalitäten entwickelt und untersucht.

Die kaiserliche Gemäldegalerie und die Anfänge des öffentlichen Kunstmuseums, Band 2

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ISBN: 9783205795346 Year: Pages: 262 Seiten Language: English|German
Publisher: Böhlau Grant: Austrian Science Fund - PUB 122
Added to DOAB on : 2014-12-04 09:02:22
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The publication focuses on the – for Europe - radical and influential new installation of the Imperial Picture Gallery in Vienna at the turn of the 19th century, a seminal time of change both for art-history and European civilization. Function, internal structure and presentation of the Imperial Picture Gallery evolved in a way that was to prove exemplary: the princely gallery was transformed into a public art museum, with a new installation at Belvedere Palace that reflected art-historical principles.

Endoplasmic Reticulcum and Its Role in Tumor Immunity

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197866 Year: Pages: 101 DOI: 10.3389/978-2-88919-786-6 Language: English
Publisher: Frontiers Media SA
Subject: Oncology --- Medicine (General)
Added to DOAB on : 2016-04-07 11:22:02
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The endoplasmic reticulum (ER) is an organelle crucial to many cellular functions and processes, including the mounting of T-cell immune responses. Indeed, the ER has a well-established central role in anti-tumor immunity. Perhaps best characterized is the role of the ER in the processing of antigen peptides and the subsequent peptide assembly into MHC class I and II molecules. Such MHC/tumor-derived peptide complexes are pivotal for the correct recognition of altered self or viral peptides and the subsequent clonal expansion of tumor-reactive T-cells. In line with the role of the ER in immunity, tumor-associated mutations in ER proteins, as well as ER protein content and localization can have both deleterious and advantageous effects on anti-tumor immune responses. For instance, loss of function of ER-aminopeptidases, that trim peptides to size for MHC, alter the MHC class I - peptide repertoire thereby critically and negatively affecting T-cell recognition. On the other hand, altered localization of ER proteins can have immune-promoting effects. Specifically, translocation of certain ER proteins to the cell surface has been shown to promote anti-tumor T-cell immunity by directing uptake of apoptotic tumor cells to professional antigen presenting cells, thereby facilitating anti-tumor T-cell immunity. These selected examples highlight a diverse and multi-faceted role of the ER in anti-tumor immunity. Molecular biological insights from the past decade have uncovered that ER components may affect tumor immunity and have invoked a variety of follow-up questions. For instance, how and why are ER proteins over-expressed in tumors? How do nucleotide and somatic mutations in ER chaperones/processing machinery affect the MHC/peptide complex and tumor cell immunogenicity? How do ER-proteins translocate to the cell surface? What if any is the potential role of extracellular ER protein in tumor immunotherapy/vaccines, and can they be delivered to the tumor cell surface by photodynamic therapy, anthracyclines or by other means? In this special research topics issue, we present basic and clinical research reports covering many aspects of ER proteins in cancer recognition by the immune system, therapy and drug development. We also present new insights into ER stress, signalling and homeostasis in immunogenic cell death in cancer, the effect of parasitic ER proteins on tumour growth, ER protein regulation of angiogenesis. A comprehensive series of articles highlight our understanding of an expanding avenue of tumour immunology and therapeutic development, which exploit a collection of proteins within the ER that are not obvious candidates for immunity against tumors.

Die kaiserliche Gemäldegalerie und die Anfänge des öffentlichen Kunstmuseums, Band 1

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ISBN: 9783205795346 Year: Pages: 310 Seiten DOI: 10.26530/OAPEN_465870 Language: English|German
Publisher: Böhlau Grant: Austrian Science Fund - PUB 121
Added to DOAB on : 2017-04-16 00:07:55
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The publication focuses on the – for Europe - radical and influential new installation of the Imperial Picture Gallery in Vienna at the turn of the 19th century, a seminal time of change both for art-history and European civilization. Function, internal structure and presentation of the Imperial Picture Gallery evolved in a way that was to prove exemplary: the princely gallery was transformed into a public art museum, with a new installation at Belvedere Palace that reflected art-historical principles.

Filamentous Bacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889450954 Year: Pages: 154 DOI: 10.3389/978-2-88945-095-4 Language: English
Publisher: Frontiers Media SA
Subject: Microbiology --- Science (General)
Added to DOAB on : 2017-07-06 13:27:36
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Filamentous phage (genus Inovirus) infect almost invariably Gram-negative bacteria. They are distinguished from all other bacteriophage not only by morphology, but also by the mode of their assembly, a secretion-like process that does not kill the host. “Classic” Escherichia coli filamentous phage Ff (f1, fd and M13) are used in display technology and bio/nano/technology, whereas filamentous phage in general have been put to use by their bacterial hosts for adaptation to environment, pathogenesis, biofilm formation, horizontal gene transfer and modulating genome stability. Many filamentous phage have a “symbiotic” life style that is often manifested by inability to form plaques, preventing their identification by standard phage-hunting techniques; while the absence or very low sequence conservation between phage infecting different species often complicates their identification through bioinformatics. Nevertheless, the number of discovered filamentous phage is increasing rapidly, along with realization of their significance. “Temperate” filamentous phage whose genomes are integrated into the bacterial chromosome of pathogenic bacteria often modulate virulence of the host. The Vibrio cholerae phage CTXf genome encodes cholera toxin, whereas many filamentous prophage influence virulence without encoding virulence factors. The nature of their effect on the bacterial pathogenicity and overall physiology is the next frontier in understanding intricate relationship between the filamentous phage and their hosts. Phage display has been widely used as a combinatorial technology of choice for discovery of therapeutic antibodies and peptide leads that have been applied in the vaccine design, diagnostics and drug development or targeting over the past thirty years. Virion proteins of filamentous phage are integral membrane proteins prior to assembly; hence they are ideal for display of bacterial surface and secreted proteins. The use of this technology at the scale of microbial community has potential to identify host-interacting proteins of uncultivable or low-represented community members. Recent applications of Ff filamentous phage extend into protein evolution, synthetic biology and nanotechnology. In many applications, phage serves as a monodisperse long-aspect nano-scaffold of well-defined shape. Chemical or chenetic modifications of this scaffold are used to introduce the necessary functionalities, such as fluorescent labels, ligands that target specific proteins, or peptides that promote formation of inorganic or organic nanostructures. We anticipate that the future holds development of new strategies for particle assembly, site-specific multi-functional modifications and improvement of existing modification strategies. These improvements will render the production of filamentous-phage-templated materials safe and affordable, allowing their applications outside of the laboratory.

Advances in Optofluidics

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ISBN: 9783038970958 9783038970965 Year: Pages: VIII, 140 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Optics and Lights
Added to DOAB on : 2018-08-15 11:37:09
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Optofluidics a niche research field that integrates optics with microfluidics. It started with elegant demonstrations of the passive interaction of light and liquid media such as liquid waveguides and liquid tunable lenses. Recently, the optofluidics continues the advance in liquid-based optical devices/systems. In addition, it has expanded rapidly into many other fields that involve lightwave (or photon) and liquid media. This Special Issue invites review articles (only review articles) that update the latest progress of the optofluidics in various aspects, such as new functional devices, new integrated systems, new fabrication techniques, new applications, etc. It covers, but is not limited to, topics such as micro-optics in liquid media, optofluidic sensors, integrated micro-optical systems, displays, optofluidics-on-fibers, optofluidic manipulation, energy and environmental applciations, and so on.

Entwicklung eines mikrofluidischen Brailledisplays

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Book Series: Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik ISSN: 18695183 ISBN: 9783731503859 Year: Volume: 32 Pages: XVI, 163 p. DOI: 10.5445/KSP/1000047135 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:58
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For cost reasons braille displays used by the visually impaired to access digital data through the sense of touch are limited to displaying one line of text. However, by using cost effective microfluidic actuators it is possible to manufacture large-scale braille displays. This work describes the working principle and the manufacturing techniques used for fabricating components of such a display and the results of an online survey revealing the user requirements regarding braille displays.

Weiterentwicklung der Beleuchtungseinheit LED-basierter Projektionssysteme

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Book Series: Spektrum der Lichttechnik / Karlsruher Institut für Technologie (KIT), Lichttechnisches Institut ISSN: 21951152 ISBN: 9783731508656 Year: Volume: 19 Pages: III, 173 p. DOI: 10.5445/KSP/1000087780 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:02:00
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This work deals with the maximum achievable output flux of LED-projectors which is limited by physics. With the objective of increasing the output flux further, the illumination unit of LED-based projectors is enhanced systematically by improving existing technologies and developing new concepts.

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