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Drying, film formation and open time of aqueous polymer dispersions : an investigation of different aspects by rheometry and inverse-micro-raman-spectroscopy (IMRS)

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ISBN: 9783866442849 Year: Pages: X, 221 S DOI: 10.5445/KSP/1000009284 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Chemical Engineering
Added to DOAB on : 2019-07-30 20:02:01
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The application properties and the final coating properties of waterborne polymer dispersions are poor compared to the ones of polymer solutions with organic solvents. This is expressed by a short open time and by inhomogeneities and defects that are visible in the final dry coating.Aim of this work is an investigation and discussion of the different aspects that are responsible for the poor application and coating properties of aqueous latex dispersions by experiments and model calculations.

Coating and drying processes for functional films in polymer solar cells - from laboratory to pilot scale

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ISBN: 9783731502012 Year: Pages: XII, 218 p. DOI: 10.5445/KSP/1000039966 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Chemical Engineering
Added to DOAB on : 2019-07-30 20:01:58
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Polymer solar cells can be produced by a continuous low cost coating and drying process. This work details a specialized experimental set-up to enable large scale roll to roll processing. Material properties such as surface energy, surface tension, and viscosity are presented and modelled. The impact of coating method, as well as process parameters (e.g. coating speed, shear rate, solvent composition) on process stability and film properties, is discussed.

In-situ Visualisierung von Oberflächendeformationen aufgrund von Marangoni-Konvektion während der Filmtrocknung

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ISBN: 9783731501480 Year: Pages: VIII, 205 p. DOI: 10.5445/KSP/1000037674 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Chemical Engineering
Added to DOAB on : 2019-07-30 20:02:00
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In the production of modern components, e.g. displays, complex substrates with e.g. conducting paths and pre-structuring are liquid coated and dried. The surfaces of such layers have to have a very well specified quality, usual. Thus it is necessary to avoid the formation of surface structures. This work presents the elementary mechanism and describes a technique for visualization to investigate surface deformations due to Marangoni-Convection during thin film drying.

Engineering Dielectric Liquid Applications

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ISBN: 9783038974024 9783038974031 Year: Pages: 170 DOI: 10.3390/books978-3-03897-403-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Technology
Added to DOAB on : 2018-12-11 10:19:26
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Dielectric liquids are used as impregnates of solid insulations or filling products in many kinds of equipment, such as transformers (power, rectifier, distribution, traction, furnace, potential, current), resistors, reactors, capacitors, cables, bushings, circuit breakers, tap changers, and thyristor cooling in power electronics, etc. Their role is paramount in the sense that their presence is one of the fundamental conditions for the proper functioning of such equipment. Similar to blood in the human body, dielectric liquids hold the responsibility of maintaining the entire equipment. The greatest challenges for engineers/maintenance planners are related to the need for methods to assess the condition of the liquid, along with how to improve equipment efficiency using chemical admixtures. The demand for environmentally friendly dielectric liquids is also rising as the environmental concerns about conventional petroleum-based fluids become increasingly more apparent.This book covers some theoretical and practical concerns related to the applications of dielectric liquids in electrical equipment. Understanding the fundamental theoretical phenomena is, therefore, important for properly designing practical liquid-filled power equipment and hardware. Graduate-level students and teachers, as well as scientists and engineers involved in power equipment design, diagnostics, and monitoring, will appreciate this systematic approach to the subject.

Flüssigprozessierung von Multischicht-OLEDs aus kleinen Molekülen

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ISBN: 9783731504696 Year: Pages: XV, 237 p. DOI: 10.5445/KSP/1000051513 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Chemical Engineering
Added to DOAB on : 2019-07-30 20:01:57
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Organic light-emitting diodes consist of several layers of organic molecules just a few nanometers thick. In future, it may become possible to change the manufacturing process from vacuum deposition to a cost-effective liquid processing. This theoretical and practical investigation focuses on the underlying processes, in particular coating and drying, as well as the factors influencing the separation of individual layers in multilayer systems consisting of small molecules.

Recent Progress in Solid Dispersion Technology

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ISBN: 9783039215010 9783039215027 Year: Pages: 204 DOI: 10.3390/books978-3-03921-502-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:15
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Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.

Model-Based Tools for Pharmaceutical Manufacturing Processes

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ISBN: 9783039284245 9783039284252 Year: Pages: 188 DOI: 10.3390/books978-3-03928-425-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-04-07 23:07:09
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The Special Issue on “Model-Based Tools for Pharmaceutical Manufacturing Processes” will curate novel advances in the development and application of model-based tools to address ever-present challenges of the traditional pharmaceutical manufacturing practice as well as new trends. This book provides a collection of nine papers on original advances in the model-based process unit, system-level, quality-by-design under uncertainty, and decision-making applications of pharmaceutical manufacturing processes.

Abiotic Stress Effects on Performance of Horticultural Crops

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ISBN: 9783039217502 9783039217519 Year: Volume: 1 Pages: 126 DOI: 10.3390/books978-3-03921-751-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Agriculture (General)
Added to DOAB on : 2019-11-05 10:43:33
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Horticultural crop yield and quality depend on genotype, environmental conditions, and production management. In particular, adverse environmental conditions may greatly affect crop performance, reducing crop yield by 50%–70%. Abiotic stresses such as cold, heat, drought, flooding, salinity, nutrient deficiency, and ultraviolet radiation affect multiple physiological and biochemical mechanisms in plants as they attempt to cope with the stress conditions. However, different crop species can have different sensitivities or tolerances to specific abiotic stresses. Tolerant plants may activate different strategies to adapt to or avoid the negative effect of abiotic stresses. At the physiological level, photosynthetic activity and light-use efficiency of plants may be modulated to enhance tolerance against the stress. At the biochemical level, several antioxidant systems may be activated, and many enzymes may produce stress-related metabolites to help avoid cellular damage, including compounds such as proline, glycine betaine, and amino acids. Within each crop species there is a wide variability of tolerance to abiotic stresses, and some wild relatives may carry useful traits for enhancing the tolerance to abiotic stresses in their progeny through either traditional or biotechnological breeding. The research papers and reviews presented in this book provide an update of the scientific knowledge of crop interactions with abiotic stresses.

Smart Nanovesicles for Drug Targeting and Delivery

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ISBN: 9783038978947 9783038978954 Year: Pages: 198 DOI: 10.3390/books978-3-03897-895-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-06-26 08:44:06
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Nanovesicles are highly-promising systems for the delivery and/or targeting of drugs, biomolecules and contrast agents. Despite the fact that initial studies in this area were performed on phospholipid vesicles, there is an ever-increasing interest in the use of other molecules to obtain smart vesicular carriers focusing on strategies for targeted delivery. These systems can be obtained using newly synthesized smart molecules, or by intelligent design of opportune carriers to achieve specific delivery to the site of action.

Drug Metabolism, Pharmacokinetics and Bioanalysis

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ISBN: 9783038979166 9783038979173 Year: Pages: 230 DOI: 10.3390/books978-3-03897-917-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-06-26 08:44:06
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Drug metabolism/pharmacokinetics and drug interaction studies have been extensively carried out in order to secure the druggability and safety of new chemical entities throughout the development of new drugs. Recently, drug metabolism and transport by phase II drug metabolizing enzymes and drug transporters, respectively, as well as phase I drug metabolizing enzymes, have been studied. A combination of biochemical advances in the function and regulation of drug metabolizing enzymes and automated analytical technologies are revolutionizing drug metabolism research. There are also potential drug–drug interactions with co-administered drugs due to inhibition and/or induction of drug metabolic enzymes and drug transporters. In addition, drug interaction studies have been actively performed to develop substrate cocktails that do not interfere with each other and a simultaneous analytical method of substrate drugs and their metabolites using a tandem mass spectrometer. This Special Issue has the aim of highlighting current progress in drug metabolism/pharmacokinetics, drug interactions, and bioanalysis.

Keywords

procainamide --- N-acetylprocainamide --- ultra-high-pressure liquid chromatography --- rat --- plasma --- pharmacokinetics --- adalimumab --- immunoprecipitation --- liquid chromatography-quadrupole TOF MS --- bioanalysis --- GB3 --- Fabry disease --- LC-QTOF-MS/MS --- B6 --- 129-Glatm1Kul/J --- cytochrome P450 --- drug interaction --- liquid chromatography-tandem mass spectrometry --- organic anion transporting polypeptide --- pharmacokinetics --- Korean red ginseng extract --- metformin --- diabetes --- drug interaction --- pharmacokinetics --- efficacy --- ethyl glucuronide --- hair --- HPLC-MS/MS --- AUDIT score --- alcohol addiction --- eurycomanone --- Eurycoma longifolia --- bioavailability --- pharmacokinetic --- anthraquinone --- glycoside --- aglycone --- LC-MS/MS --- plasma --- protein precipitation --- loxoprofen --- CYP --- UGT --- human liver microsomes --- LC-HR/MS --- mematine --- drug interaction --- liquid chromatography-tandem mass spectrometry --- pharmacokinetics --- biopharmaceuticals --- drying technology --- protein stability --- bioavailability --- pharmacokinetics --- DA-9805 --- saikosaponin a --- paeonol --- imperatorin --- pharmacokinetics --- brain distribution --- Osthenol --- CYP --- UGT --- human liver microsomes --- glucuronidation --- Stauntonia hexaphylla leaf extract --- YRA-1909 --- pharmacokinetics --- chlorogenic acid --- neochlorogenic acid --- cryptochlorogenic acid --- caffeic acid --- caffeic acid O-glucuronides --- LC-MS/MS --- aceclofenac --- diclofenac --- esomeprazole --- pharmacokinetics --- gastric ulcer --- acetyl tributyl citrate --- pharmaceutical excipient --- pharmacokinetics --- metabolic stability --- plasma

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