Search results: Found 4

Listing 1 - 4 of 4
Sort by
Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday

Authors: ---
ISBN: 9783038974161 / 9783038974178 Year: Pages: 256 DOI: 10.3390/books978-3-03897-417-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Biochemistry
Added to DOAB on : 2019-06-26 08:44:06
License:

Loading...
Export citation

Choose an application

Abstract

Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.

Keywords

Zingiber officinale --- gingerols --- cytotoxic activity --- oleanolic acid --- high-fat high-carbohydrate diet --- pre-diabetes --- glucose homeostasis --- insulin resistance --- atherosclerosis --- ROS --- HUVECs --- LOX-1 --- alkaloid --- granatane --- N-methylcadaverine --- N-methylpiperidine. reductive deamination --- Mucorales --- Rhizopus arrhizus --- sterol pattern --- antifungal effectivity --- gas chromatography-mass spectrometry (GC-MS) --- posaconazole --- sterol biosynthesis --- sterol 14?-demethylase --- sterol C24-methyltransferase --- mechanism-based inactivators --- antifungals --- azoles --- antiparasitic drugs --- human African trypanosomiasis --- Chagas disease --- synthesis --- squalene cyclase --- cycloartenol synthase --- triterpene --- fern --- Polystichum --- terpene --- isoprenoid --- divalent metal co-factor ligation --- antioxidant --- cholesterol --- degeneration --- oxysterol --- retina --- Smith-Lemli-Opitz syndrome --- algal sterols --- ergosterol biosynthesis --- infectious disease --- lipidomics --- oxyphytosterol --- pharmacognosy --- phytosterol --- sterolomics --- lupeol --- keratinocytes --- fibroblasts --- wound healing --- cell migration --- UV-radiation --- ZnO --- toxicity --- sterol content --- cholesterol --- leishmania --- solanaceae --- withanolides --- aurelianolides --- phytosterols --- mesocarp --- oilseed --- maturity --- pod-blast --- ?-tocopherol --- oil bodies --- campesterol --- stigmasterol --- ?-sitosterol --- sterol --- C4-demethylation complex (C4DMC) --- 4-methylsterol --- hormone --- steroid --- development --- genetic disease --- bile alcohol --- cholestanoic acid --- oxysterol --- sterolomics --- enzyme-assisted derivatization --- electrospray ionization-mass spectrometry --- Girard reagent --- n/a

Solid Phase Extraction: State of the Art and Future Perspectives

Author:
ISBN: 9783039211586 / 9783039211593 Year: Pages: 176 DOI: 10.3390/books978-3-03921-159-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

This book is a collection of 13 innovative papers describing the state of the art and the future perspectives in solid-phase extraction covering several analytical fields prior to the use of gas or liquid chromatographic analysis. New sorptive materials are presented including carbon nanohorn suprastructures on paper support, melamine sponge functionalized with urea–formaldehyde co-oligomers, chiral metal–organic frameworks, UiO-66-based metal–organic frameworks, and fabric phase sorptive media for various applications. Solid-phase extraction can be applied in several formats aside from the conventional cartridges or mini-column approach, e.g., online solid-phase extraction, dispersive solid-phase microextraction, and in-syringe micro-solid-phase extraction can be very helpful for analyte pre-concentration and sample clean-up. Polycyclic musks in aqueous samples, 8-Nitroguanine in DNA by chemical derivatization antibacterial diterpenes from the roots of salvia prattii, perfluoroalkyl substances (PFASs) in aater samples by bamboo charcoal-based SPE, parabens in environmental water samples, benzotriazoles as environmental pollutants, organochlorine pesticide residues in various fruit juices and water samples and synthetic peptide purification are among the applications cited in this collection. All these outstanding contributions highlight the necessity of this analytical step, present the advantages and disadvantages of each method and focus on the green analytical chemistry guidelines that have to be fulfilled in current analytical practices.

Innovative Extraction Techniques and Hyphenated Instrument Configuration for Complex Matrices Analysis

Authors: --- ---
ISBN: 9783039210848 / 9783039210855 Year: Pages: 308 DOI: 10.3390/books978-3-03921-085-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Chemical Engineering
Added to DOAB on : 2019-06-26 08:44:06
License:

Loading...
Export citation

Choose an application

Abstract

The present Special Issue, “Innovative Extraction Techniques and Hyphenated Instrument Configuration for Complex Matrices Analysis”, aims to collect and to disseminate some of the most significant and recent contributions in the interdisciplinary area of innovative extraction procedures from complex matrices followed by validated analytical methods using hyphenated instrument configurations to support the optimization of the whole process and the scale-up possibility

Keywords

branched-chain keto acids --- serum --- muscle --- HPLC-Q-TOF/MS --- wood --- odor --- volatile organic compounds --- gas chromatography-olfactometry --- Wuyi Rock tea --- quality --- UPLC-QTOF MS --- UPLC-QqQ MS --- metabolite profiling --- metabolomics --- cluster analysis --- cultivars --- Lycium ruthenicun --- flavonoid --- ruthenicunoid A --- SIRT1 --- Asphodeline lutea --- HPLC-PDA --- heavy metals --- tyrosinase --- diabetes --- neurodegenerative disease --- color analysis --- pigments --- MAE --- HPLC-PDA --- SFE --- Thymus algeriensis --- rare earth elements --- flow injection --- inductively coupled plasma-mass spectrometry --- seawater --- Hericium erinaceuns mycelium --- high-speed counter-current chromatography (HSCCC) --- genistein --- daidzein --- Fe3O4 --- modification --- alginate --- alkaloid --- ultrasound assisted extraction --- gelatin --- actinidin --- bovine hide --- physicochemical properties --- gel strength --- Semen Cuscutae --- ultra-high-performance liquid chromatography coupled to electrospray ionization mass spectrometry --- chlorogenic acids --- flavonoids --- steamed Panax notoginseng --- saponins --- extraction --- optimization --- antioxidant activity --- response surface methodology --- hematopoiesis --- microwave processing --- response surface methodology --- minor ginsenosides --- blood-enriching activity --- hemostatic activity --- ionic liquids --- sample preparation --- microextraction --- solid-phase microextraction --- dispersive liquid-liquid microextraction --- single-drop microextraction --- stir bar sorptive extraction --- stir cake sorptive extraction --- rosuvastatin --- metformin --- HILIC --- LC-MS --- therapeutic drug monitoring --- oolong tea --- Tieguanyin tea cultivar --- metabolite profiling --- UPLC-QTOF MS --- metabolomics --- Ajuga genevensis --- near-infrared spectroscopy --- dry extract --- fluid bed process --- microNIR --- in-line monitoring --- total polyphenolic content --- antioxidant --- flavonoids --- mouse melanoma B16 cells --- Panax notoginseng --- surfactant --- n/a --- ultra-high-performance liquid chromatography tandem mass spectrometry --- GHB --- GHB glucuronide --- nails --- endogenous values --- walnut septum --- polyphenols --- phytosterols --- HPLC-MS/MS --- Ultra-Turrax extraction --- biological activity --- antioxidant activity --- experimental design --- optimization --- phytochemicals

Qualitative and Quantitative Analysis of Bioactive Natural Products 2018

Author:
ISBN: 9783038977889 Year: Pages: 374 DOI: 10.3390/books978-3-03897-789-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Science (General)
Added to DOAB on : 2019-04-05 10:34:31
License:

Loading...
Export citation

Choose an application

Abstract

Throughout most of history, medicinal plants and their active metabolites have represented a valuable source of compounds used to prevent and to cure several diseases. Interest in natural compounds is still high as they represent a source of novel biologically/pharmacologically active compounds. Due to their high structural diversity and complexity, they are interesting structural scaffolds that can offer promising candidates for the study of new drugs, functional foods, and food additives.Plant extracts are a highly complex mixture of compounds and qualitative and quantitative analyses are necessary to ensure their quality. Furthermore, greener methods of extraction and analysis are needed today.This book is based on articles submitted for publication in the Special Issue entitled “Qualitative and Quantitative Analysis of Bioactive Natural Products” that collected original research and reviews on these topics.

Keywords

Talaromyces pinophilus --- talarodiolide --- macrodiolides --- GC/MS --- secondary metabolites --- anthocyanins --- red cabbage --- recycling preparative high performance liquid chromatography --- stability --- UHPLC-MS/MS --- decursin --- decursinol angelate --- nodakenin --- decursinol --- Ginkgo biloba Extract (GBE) --- chromatogram-bioactivity correlation --- bioactive compounds --- endothelial function --- wine --- volatile compounds --- terrain conditions --- odor-activity values --- SPME-GC/MS --- Bolbostemma paniculatum --- identification --- LTQ-Orbitrap --- UPLC --- multivariate statistical analysis --- cannabidiol --- CBD oil --- terpenes --- hemp seed oil --- GC-MS --- HPLC-Q-Exactive-Orbitrap-MS --- Rossa da inverno sel. Rojo Duro onion cultivar --- geographical origin --- amino acids content --- HPLC analysis --- statistical evaluations --- food traceability --- aleuritolic acid --- autophagy --- apoptosis --- HPLC --- Curcuma longa --- turmeric --- curcuminoids --- turmerone --- quantification --- Quercus acuta leaf --- antioxidant --- antibacterial activity --- Staphylococcus aureus --- Erigeron breviscapus extract --- UPLC-ESI-MS/MS --- cerebral ischemia reperfusion injury --- scutellarin --- scutellarein --- HPLC --- Podospermum --- Scorzonera --- triterpenes --- ginseng berry extract --- ginsenosides --- stereoselective and simultaneous analysis --- pharmacokinetics --- oral administration --- saffron --- crocins --- UHPLC analysis --- separation optimisation --- artificial neural network --- response surface methodology --- bioactive natural compounds --- secondary metabolites --- Alzheimer’s disease --- Olea europaea L. --- liquid chromatography --- gas chromatography --- mass spectrometry --- secondary metabolites --- olive leaves --- Moroccan region --- phenolic compounds --- liquid chromatography-mass spectrometry --- chemometrics --- metabolic profiling --- Sorbus --- fruit powders --- phenolic compounds --- carotenoids --- sugars --- organic acids --- chili --- capsaicinoids --- phenolics --- free radical-scavenging --- geographical variation --- 1-triacontanol --- HPLC-ELSD --- biostimulant --- method validation --- Myristica fragrans --- nutmeg --- essential oil --- ionic liquids --- hydrodistillation --- MODDE experimental design --- rice --- phenolic compounds --- phenolic acids --- flavonoids --- anthocyanins --- proanthocyanidins --- antioxidant activity --- extraction --- HPLC methods --- phenolic compounds --- Spondias spp. --- UPLC-MS --- antioxidant capacity --- Iris lactea Pall. var. chinensis (Fisch.) Koidz. --- HPLC-Q-TOF-MS/MS --- qualitative analysis --- quantitative analysis --- C-glycosylflavone --- traditional Chinese medicine decoction --- quality evaluation --- UPLC-QTOF-MS --- UFLC-QQQ-MS --- ShenFu prescription decoction

Listing 1 - 4 of 4
Sort by
Narrow your search

Publisher

MDPI - Multidisciplinary Digital Publishing Institute (4)


License

CC by-nc-nd (4)


Language

eng (4)


Year
From To Submit

2019 (4)