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Magnetic Resonance Imaging of Healthy and Diseased Brain Networks

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889194353 Year: Pages: 365 DOI: 10.3389/978-2-88919-435-3 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-01-19 14:05:46
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An important aspect of neuroscience is to characterize the underlying connectivity patterns of the human brain (i.e., human connectomics). Over the past few years, researchers have demonstrated that by combining a variety of different neuroimaging technologies (e.g., structural MRI, diffusion MRI and functional MRI) with sophisticated analytic strategies such as graph theory, it is possible to noninvasively map the patterns of structural and functional connectivity of human whole-brain networks. With these novel approaches, many studies have shown that human brain networks have nonrandom properties such as modularity, small-worldness and highly connected hubs. Importantly, these quantifiable network properties change with age, learning and disease. Moreover, there is growing evidence for behavioral and genetic correlates. Network analysis of neuroimaging data is opening up a new avenue of research into the understanding of the organizational principles of the brain that will be of interest for all basic scientists and clinical researchers. Such approaches are powerful but there are a number of challenging issues when extracting reliable brain networks from various imaging modalities and analyzing the topological properties, e.g., definitions of network nodes and edges and reproducibility of network analysis. We assembled contributions related to the state-of-the-art methodologies of brain connectivity and the applications involving development, aging and neuropsychiatric disorders such as Alzheimer’s disease, schizophrenia, attention deficit hyperactivity disorder and mood and anxiety disorders. It is anticipated that the articles in this Research Topic will provide a greater range and depth of provision for the field of imaging connectomics.

Graph Theory - Advanced Algorithms and Applications

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ISBN: 9789535137726 9789535137733 9789535139843 Year: Pages: 194 DOI: 10.5772/65595 Language: English
Publisher: IntechOpen
Subject: Mathematics
Added to DOAB on : 2019-10-03 07:51:50

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This book is prepared as a combination of the manuscripts submitted by respected mathematicians and scientists around the world. As an editor, I truly enjoyed reading each manuscript. Not only will the methods and explanations help you to understand more about graph theory, but I also hope you will find it joyful to discover ways that you can apply graph theory in your scientific field. I believe the book can be read from the beginning to the end at once. However, the book can also be used as a reference guide in order to turn back to it when it is needed. I have to mention that this book assumes the reader to have a basic knowledge about graph theory. The very basics of the theory and terms are not explained at the beginner level. I hope this book will support many applied and research scientists from different scientific fields.

Ontologie-basierte Monosemierung

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ISBN: 9783866449589 Year: Pages: XVI, 331 p. DOI: 10.5445/KSP/1000031500 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Business and Management
Added to DOAB on : 2019-07-30 20:01:59
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According to the Semantic Web a formal representation of knowledge is described by an ontology. This formal representation enables a unique identification of elements within an ontology. By the use of natural language for element annotation, ambiguity occurs and a unique element identification based on natural language cannot be guaranteed. This book describes an approach to identify the most relevant element described by a natural language term by reducing the aspect of ambiguity to a minimum.

Neuropsychology and Neuropsychiatry of Neurodegenerative Disorders

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197385 Year: Pages: 190 DOI: 10.3389/978-2-88919-738-5 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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This book compiles all articles within the Research Topic "Neuropsychology and neuropsychiatry of neurodegenerative disorders" published in the journal Frontiers in Aging Neuroscience. The call was launched in 2014 and closed in 2015 with 21 articles published. Papers deal on several important topics of neuropsychology -such as language and visuospatial functions- and neuropsychiatry - such us the emotional or motivational spheres - , and the interphase between them. There are also articles on psychometry, brain morphometry, brain connectivity, diagnostic tests and interventional studies. All these articles are focused on neurodegenerative conditions, mostly Alzheimer’s disease and Parkinson’s disease. Interestingly, several articles addressed the early stages of these diseases. All together, this Research Topic provides a rich perspective of the research made today around neuropsychological and neuropsychiatric aspects of neurodegenerative diseases. We hope readers enjoy this collection of articles.

Foundations of Software Science and Computation Structures: 21st International Conference, FOSSACS 2018, Held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2018, Thessaloniki, Greece, April 14–20, 2018. Proceedings

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Book Series: Theoretical Computer Science and General Issues ISSN: 0302-9743 ISBN: 9783319893655 9783319893662 Year: Pages: 583 DOI: https://doi.org/10.1007/978-3-319-89366-2 Language: English
Publisher: Springer Grant: ETAPS e.V.
Subject: Computer Science
Added to DOAB on : 2018-06-26 16:52:58
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This book constitutes the proceedings of the 21st International Conference on Foundations of Software Science and Computational Structures, FOSSACS 2018, which took place in Thessaloniki, Greece, in April 2018, held as part of the European Joint Conference on Theory and Practice of Software, ETAPS 2018.The 31 papers presented in this volume were carefully reviewed and selected from 103 submissions. The papers are organized in topical sections named: semantics; linearity; concurrency; lambda-calculi and types; category theory and quantum control; quantitative models; logics and equational theories; and graphs and automata.

Symmetry Measures on Complex Networks

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ISBN: 9783038424987 9783038424994 Year: Pages: 510 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Mathematics
Added to DOAB on : 2017-10-02 11:56:21
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Symmetry is found everywhere, to a greater or lesser degree. It is essential in all sciences and also as the basic substrate in all arts. The same happens with Complex Networks, which are the majority of all those that interest for advanced knowledge, that is, for research. That is why these two themes have been unified here, whose intersection we are dealing with: in its first part, of fundamentals, and in its second part of applications, which are multiple in the world today.

Information Theory in Neuroscience

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ISBN: 9783038976646 Year: Pages: 280 DOI: 10.3390/books978-3-03897-665-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Mathematics --- Science (General)
Added to DOAB on : 2019-03-21 15:50:41
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As the ultimate information processing device, the brain naturally lends itself to being studied with information theory. The application of information theory to neuroscience has spurred the development of principled theories of brain function, and has led to advances in the study of consciousness, as well as to the development of analytical techniques to crack the neural code—that is, to unveil the language used by neurons to encode and process information. In particular, advances in experimental techniques enabling the precise recording and manipulation of neural activity on a large scale now enable for the first time the precise formulation and the quantitative testing of hypotheses about how the brain encodes and transmits the information used for specific functions across areas. This Special Issue presents twelve original contributions on novel approaches in neuroscience using information theory, and on the development of new information theoretic results inspired by problems in neuroscience.

Lignans

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ISBN: 9783038979081 / 9783038979098 Year: Pages: 384 DOI: 10.3390/books978-3-03897-909-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General) --- Organic Chemistry
Added to DOAB on : 2019-06-26 10:09:00
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Lignans are a class of natural products found mainly in plants. They have a wide variety of structures and exhibit a range of potent biological activities. Lignans are also well-known components of a number of widely eaten foods and are frequently studied for their dietary impact. Owing to these factors, lignans have been extensively studied by scientists from a large number of disciplines. This collection of research and review articles describes topics ranging in scope from the recent isolation and structural elucidation of new lignans, strategies towards the chemical synthesis of lignans, assessment of their biological activities and potential for further therapeutic development. Research showing the impact of lignans in the food and agricultural industries is also presented.

Keywords

lignans --- chemometrics --- neolignans --- flavonolignans --- chemical space --- drug-like --- Lespedeza cuneata --- lignan glycoside --- flavonoid glycoside --- cytotoxicity --- adipocyte and osteoblast differentiation --- Bursera --- Burseraceae --- lignans --- lignan --- molecular dynamics --- intermolecular interactions --- graph theory --- lignans --- heilaohu --- tujia ethnomedicine --- chemical characterization --- cytotoxicity --- antioxidant --- cultivar --- environment --- flax --- flavonol --- genetic --- hydroxycinnamic acid --- lignan --- seed --- aryldihydronaphthalene lignan --- arylnaphthalene lignan --- oxidation --- synthesis --- lignans --- dibenzyl butyrolactones --- anti-proliferative --- acyl-Claisen --- stereoselective synthesis --- Schisandra rubriflora --- Schisandra chinensis --- red-flowered Chinese magnolia vine --- Chinese magnolia vine --- lignans --- phytochemical analysis --- UHPLC-MS/MS --- anti-inflammatory activity --- LOX --- COX --- sPLA2 --- lignans --- neolignans --- Lauraceae --- chemical components --- chemical structures --- dietary lignans --- national databases --- food groups --- dietary intake --- harmonized databases --- lignans --- in silico studies --- podophyllotoxin --- antibacterial activity --- acetylcholinesterase inhibitors --- antioxidant activity --- cytotoxicity --- natural products --- total synthesis --- lignan --- Bursera fagaroides --- podophyllotoxin-type lignans --- cell cycle --- cell migration --- epiboly --- microtubules --- F-actin --- cancer --- lignans --- animal health --- cattle --- enterolignan --- human health --- pharmacokinetic --- ruminant --- secoisolariciresinol diglucoside --- Lignan --- bitterness --- taste-active compound --- quantification --- oak ageing --- lignans --- norlignans --- 9-norlignans --- semisynthesis --- hydroxymatairesinol --- bioactivity --- lignans --- oxidation --- lignans --- diet --- antioxidants --- health promotion --- chronic diseases --- Schisandrae Chinensis Fructus --- wild --- cultivated --- multiple bioactive components --- simultaneous quantitation

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