Search results: Found 7

Listing 1 - 7 of 7
Sort by
New Approaches to the Pathogenesis of Sudden Intrauterine Unexplained Death and Sudden Infant Death Syndrome

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453016 Year: Pages: 104 DOI: 10.3389/978-2-88945-301-6 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Neurology
Added to DOAB on : 2018-02-27 16:16:45
License:

Loading...
Export citation

Choose an application

Abstract

Sudden Infant Death Syndrome (SIDS) is the leading cause of death among infants in the first year of age. The more known definition of SIDS is the sudden unexpected death of an infant less than 1 year of age, with onset of the fatal episode apparently occurring during sleep, that remains unexplained after a thorough investigation, including performance of a complete autopsy and review of the circumstances of death and the clinical history. Despite the success of the “Back to Sleep” campaigns to reduce the risks introduced worldwide, the frequency of SIDS (striking one infant every 750-1,000 live births) has not significantly declined in the last years. Sudden Intrauterine Unexplained Death Syndrome (SIUDS), referring to fetuses that die unexpectedly, particularly in the last weeks of gestation, without any cause even after a complete autopsy, including examination of the placental disk, umbilical cord and fetal membranes, has a six-eightfold greater incidence than that of SIDS. Even if the pathogenetic mechanism of these deaths has not yet been determined, the neuropathology seems to be a consistent substrate in both SIUDS and SIDS. Subtle common developmental abnormalities of brainstem nuclei checking the vital functions have been highlighted, frequently related to environmental risk factors, such as cigarette smoke, air and water pollution, pesticides, food contamination, etc. Exogenous toxic factors can in fact interact in complex ways with the genetic constitution of the infant leading to polymorphisms and/or mutations of specific genes (as polymorphisms of the serotonin transporter gene 5-HTT, the regulator of the synaptic serotonin concentration, and of the PHOX2B, the key gene in the Congenital Central Hypoventilation Syndrome). These interactions can directly injure the development of the autonomic nervous system, frequently resulting in hypoplasia of the vital brainstem centers, and consequently in sudden death. It is very important to continue studying these syndromes and in particular identify all possible congenital alterations and their correlation with the exposure to environmental risk factors, in order to reduce their incidence and mitigate the surrounding social concern. The goal of this research topic is to propose new approaches to explain the pathogenesis of both SIUDS and SIDS and consequently new prevention strategies to decrease the incidence of these unexpected and very devastating events for families. Expert authors in the Topic field are encouraged to submit original research articles aimed to widen the current knowledge on the pathological substrates of these deaths, also considering the correlations with possible risk factors. Submissions of hypotheses, opinions and commentaries are also welcome. This Research Topic would lead to development of targeted risk-lowering strategies to reduce the incidence of both SIUDS and SIDS. Furthermore, the adoption of appropriate preventive measures could also lead to improve the quality of life in adults, promoting active and healthy aging.

Global Health Research in an Unequal World

Authors: --- ---
ISBN: 9781786390042 9781786390059 Year: Pages: 275 Language: English
Publisher: CABI CAB International Grant: Wellcome Trust
Subject: Sociology --- Philosophy
Added to DOAB on : 2019-01-15 13:34:15
License:

Loading...
Export citation

Choose an application

Abstract

This book is a collection of fictionalised case studies of everyday ethical dilemmas and challenges, encountered in the process of conducting global health research in places where the effects of global, political and economic inequality are particularly evident. It is a training tool to fill the gap between research ethics guidelines, and their implementation 'on the ground'. The case studies, therefore, focus on 'relational' ethics: ethical actions and ideas that emerge through relations with others, rather than in regulations.

Surgical Ophthalmic Oncology

Authors: --- ---
ISBN: 9783030187576 / 9783030187569 Year: Pages: 216 DOI: https://doi.org/10.1007/978-3-030-18757-6 Language: English
Publisher: Springer
Subject: Ophthalmology
Added to DOAB on : 2019-10-09 12:31:33
License:

Loading...
Export citation

Choose an application

Abstract

Designed as an easy-to-use, practical guide to tumors of the eye, lids, and orbit, this open access book comprehensively addresses surgical treatment and management of diseases related to ophthalmic oncology. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is an ideal reference for general ophthalmologists, surgeons, fellows and trainees around the world who encounter these diseases in the care of their patients. Notably, this book includes considerations for those ophthalmologists offering subspecialty care in environments with limited access to advanced technology and instrumentation. Individual chapters address diagnostic indications, pre-operative and post-operative concerns, and provide detailed explanations of surgical techniques required to manage various eye cancer ailments with help of ample illustrations. High-quality videos included throughout the book provide readers with the opportunity to review surgical steps in real-time as a learning tool. Chapters thoroughly cover tumors of eyelid, cornea and conjunctiva, orbit as well as intraocular tumors, while later chapters discuss ophthalmic radiation therapy. The book concludes with a section on ophthalmic pathology which details essential guidelines on relevant aspects from specimen collection and transport, to interpretation of the pathology report.Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is a unique and necessary valuable resource for ophthalmologists, trainees, and related medical professionals working in underserved areas in providing quality care for patients suffering from ocular cancers.

Recent Advances in Water Management: Saving, Treatment and Reuse

Authors: ---
ISBN: 9783038970316 / 9783038970323 Year: Pages: 208 DOI: 10.3390/books978-3-03897-032-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Environmental Sciences
Added to DOAB on : 2019-08-28 11:21:28
License:

Loading...
Export citation

Choose an application

Abstract

This book is a printed edition of the Special Issue Recent Advances in Water Management: Saving, Treatment and Reuse that was published in Water

Keywords

guidelines --- contaminated sites --- risk assessment --- China --- ferrous iron --- ferrous sulfide --- hydrogen sulfide --- odor control --- pumping mains --- sewerage --- pharmaceuticals --- micropollutant removal --- tezontle --- filter media --- active sites --- trickling filter --- anaerobic digester --- swine wastewater --- organic matter --- COD --- decomposition analysis --- global patent data --- research and development strategy --- water treatment technology --- anammox bacteria --- wastewater treatment --- nitrification --- denitrification --- zeolite --- combined sewer --- wastewater treatment --- microbiological quality --- surface water --- river --- lignin --- delignification --- pulp-and-paper-mill c --- wastewater --- white rot fungi --- B. adusta --- P. crysosporium --- foreign countries --- agricultural occupations --- water --- environmental education --- surveys --- sustainability --- milk production --- water --- footprint --- water recycling --- conservation --- partitioning --- efficiency --- forest waste --- palm mulch --- constructed wetlands --- vertical flow --- water treatment --- passive treatment systems --- anaerobic processes --- constructed wetlands --- ornamental plants --- treated wastewater reuse --- advanced oxidation processes (AOPs) --- activated carbon adsorption --- carbamazepine toxicity --- conventional treatment processes --- membrane technology --- occurrence --- food industry --- anticorrosive agent --- benzotriazole --- emerging contaminant --- oxygen injection --- Pb(II) --- nano illite/smectite clay --- adsorption kinetics --- adsorption thermodynamic

Prospects for Schistosomiasis Elimination

Authors: ---
ISBN: 9783039213573 / 9783039213580 Year: Pages: 308 DOI: 10.3390/books978-3-03921-358-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Internal medicine
Added to DOAB on : 2019-12-09 11:49:15
License:

Loading...
Export citation

Choose an application

Abstract

Current efforts to limit the ravages of schistosomiasis are pushing the world closer to eliminating a chronic infection that has been associated with human life in the tropics since time immemorial. This notwithstanding, the disease remains a scourge for large populations in sub-Saharan Africa, Latin America, and Southeast Asia, and the main part of this book is made up by papers dealing with its current distribution, discussing ways and means to establish and implement improved control approaches. While chemotherapy limits the symptoms caused by schistosomiasis, the number of infected people will not decrease until the parasite's life cycle is interrupted. To that end, some papers focus on the intermediate snail host, which is notoriously difficult to control, while others discuss human hygiene and sanitation. The latter approach not only prevents infection through avoiding people being infected from the snail, but more importantly, also stops people infecting the snail by leaving contagious feces and urine in nature. With morbidity reduced by chemotherapy, the immediate target now is the interruption of transmission to be achieved by new tools, such as the novel chemotherapies, improved diagnostics (for humans, animals, and snails), and vaccines discussed in several of the papers. As made clear in this book, a complex infection requires new tools as well as work on many fronts, above all; however, a clear idea is needed as to how to skillfully combine the tools available and sustain implemented control activities.

Keywords

schistosomiasis --- Schistosoma --- vaccine --- zoonosis --- Asia --- Africa --- domestic animals --- buffalo --- cattle --- sheep --- goats --- Côte d’Ivoire --- coverage rate --- praziquantel --- preventive chemotherapy --- Schistosoma haematobium --- Schistosoma mansoni --- schistosomiasis --- diagnosis --- control and elimination --- DNA --- polymerase chain reaction --- schistosomiasis --- control --- elimination --- Africa --- operational research --- goals --- guidelines --- schistosomiasis --- vector control --- snail resistance --- gene drive --- transgenic snail --- schistosomiasis --- Kato-Katz --- POC-CCA --- young adults --- soil-transmitted helminths --- n/a --- Mayuge --- MDA coverage --- praziquantel --- S. mansoni --- systematic non-compliance --- treatment-opportunities --- Uganda --- climate change --- schistosomiasis --- distribution --- intermediate snail host --- transmission --- modelling --- schistosomiasis --- soil-transmitted-helminthiasis --- mapping --- preventive chemotherapy --- transmission control --- Gabon --- Central Africa --- schistosomiasis --- vaccine --- Sm14 --- FABP --- Schistosoma japonicum --- Oncomelania hupensis --- snail --- 28S ribosomal DNA --- PCR --- loop-mediated isothermal amplification (LAMP) --- pooled samples --- China --- schistosomiasis --- elimination --- praziquantel --- artemether --- combination therapy --- phylogeography --- Bulinus truncatus --- planorbidae --- Africa --- schistosomiasis --- neglected tropical diseases --- WIPO Re:Search --- BIO Ventures for Global Health --- cross-sector collaboration --- capacity-building --- drug discovery --- public-private partnerships --- GIS --- remote-sensing --- satellite --- international space station --- ECOSTRESS --- worldview --- spatio-temporal epidemiology --- climate change --- parasite --- schistosomiasis, leishmaniasis --- n/a --- schistosomiasis --- systems epidemiology --- systems thinking --- complexity --- neglected tropical diseases --- interdisciplinarity --- Schistosomiasis mansoni --- Caribbean --- elimination --- snail control --- Biomphalaria glabrata --- Schistosoma mekongi --- Neotricula aperta --- snail --- Cambodia --- Lao PDR --- elimination --- Asia --- control --- elimination --- epidemiology --- Schistosoma japonicum --- Schistosoma malayensis --- Schistosoma mekongi --- schistosomiasis --- Schistosomiasis --- Philippines --- schistosomiasis elimination --- S. japonicum zoonosis --- bovines --- schistosomiasis elimination --- snail control --- high-sensitivity diagnostics --- chemotherapy --- vaccine development --- health education --- sanitation

The Impact of Caffeine and Coffee on Human Health

Authors: ---
ISBN: 9783039218349 / 9783039218356 Year: Pages: 322 DOI: 10.3390/books978-3-03921-835-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2020-01-07 09:21:22
License:

Loading...
Export citation

Choose an application

Abstract

The purpose of this Special Issue is to provide a thorough and up-to-date presentation of research investigating the impact of coffee and/or caffeine intake on various health outcomes. Areas of interest include, but are not limited to, the following topics: Human clinical trials of coffee or caffeine use in relation to disease or intermediate phenotypes. Epidemiological studies of habitual coffee or caffeine intake in relation to human health, among the general public, as well as, among special populations (i.e., children, pregnant women, diabetics, cancer patients, hypertensives, etc.). Mechanisms of action of nutrients and other bioactive components of coffee/caffeine. Studies integrating genetic or physiological markers of coffee/caffeine intake to investigations of coffee and health.

Keywords

accidental death --- caffeine --- caffeine intoxication --- intoxication --- Suicide --- HIV-HCV co-infection --- liver fibrosis --- coffee --- alcohol consumption --- coffee --- tea --- European Prospective Investigation into Cancer and Nutrition --- 24-h dietary recall --- whole-blood --- mRNA --- transcriptomics --- gene expression --- coffee --- the Norwegian Women and Cancer Cohort (NOWAC) --- caffeine --- myocardial perfusion --- coronary artery disease --- adenosine --- regadenoson --- dipyridamole --- caffeine intake --- assisted reproduction techniques --- risk factors --- implantation --- clinical pregnancy --- live birth --- epidemiology --- bias --- causation --- coffee --- pregnancy --- coffee --- depression --- cohort study --- Mendelian Randomization --- coffee --- caffeine --- behavior --- causality --- genetic epidemiology --- epidemiological methods --- cardiovascular disease --- coffee consumption --- gene-diet interaction --- longevity --- NADH dehydrogenase --- polymorphism --- serum chloride levels --- CYP1A2 --- ADORA2A --- time trial performance --- caffeine metabolism --- pharmacological ergogenic aid --- polymorphism --- anxiety --- ergogenic --- adenosine receptor --- cytochrome P450 --- caffeine --- pharmacogenomics --- coffee --- caffeine --- chlorogenic acids --- phenolic --- cognition --- cognitive --- mood --- age --- sex --- caffeine --- wine --- chocolate --- aging --- cognition --- adult --- coffee --- hearing --- protection --- tinnitus --- Caffeine --- placebo --- sport --- exercise --- health --- expectancy --- cognitions --- caffeine --- coffee --- systematic review --- pregnancy --- safety --- individual responses --- ergogenic aid --- supplement --- did not respond --- responders --- n/a --- caffeine --- coffee --- tea --- soda --- energy drinks --- mate --- guidelines --- country --- consumption --- population --- public policy --- coffee --- caffeine --- lipids --- biomarkers --- trial --- lysophosphatidylcholine --- lipidomics --- n/a

Addressing Food and Nutrition Security in Developed Countries

Authors: ---
ISBN: 9783039212811 / 9783039212828 Year: Pages: 427 DOI: 10.3390/books978-3-03921-282-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

The Addressing Food and Nutrition Security in Developed Countries Special Issue is a collection of papers from researchers in counties with developed economies who are responding to increasing prevalence of food insecurity. Food insecurity is relatively hidden, and the real extent of the problem is likely to be underestimated in many of these countries. Novel methods to estimate the prevalence of food insecurity in the face of no routine measurement are presented. Population surveys highlight adverse mental health outcomes and new and emerging subgroups that are experiencing food insecurity. Understanding the factors associated with food insecurity and how people cope is extremely important when considering how best to address the problem. Readers can become familiar with the lived experience of food insecurity in some countries—essential intelligence for effective policy and interventions. The extent of food banking operations and the nature of the charitable response in some countries is also described. Country-specific research highlights the importance of understanding the cultural and external environmental context. The influence the cost of food and budgetary tools on diet and food insecurity suggests opportunities for intervention. Researchers calls for social protection and high-quality dignified responses to address this complex public health problem.

Keywords

food insecurity --- charitable food services --- food charity --- food system --- nutrition --- voluntary failure --- INFORMAS --- diet prices --- food affordability --- Pacific diets --- M?ori diets --- food security --- food insecurity --- mental health --- depression --- women --- scoping review --- food bank --- food insecurity --- welfare recipients --- poverty --- food supply --- food aid --- food insecurity --- disaster --- family health --- Hurricane Katrina --- mental health --- physical health --- social support --- Asian Americans --- California Health Interview Survey --- food security --- Supplemental Nutrition Assistance Program (SNAP) --- acculturation --- English language use --- food insecurity --- food security --- Indigenous population --- ageing --- Indigenous --- food assistance --- food insecurity --- food charity --- food service --- social enterprise models --- food insecurity --- low-to-middle income --- experience --- mixed methodology research --- rural --- food supply --- food security --- obesity --- food insecurity --- stressors --- stressful life events --- access to food --- food equality --- Healthy Diets ASAP tool --- food security --- food prices --- diet affordability --- rural communities --- INFORMAS --- food insecurity --- monitoring --- surveillance --- determinants --- path diagram --- food security --- food insecurity --- Aboriginal and Torres Strait Islander population --- children --- urban --- experiences --- coping strategies --- household food insecurity --- food poverty --- Scotland --- low income --- families --- children --- women --- older people --- qualitative --- food aid --- charity --- Finland --- welfare state --- food aid recipient --- deservingness --- disadvantages --- inequality --- food security --- diet-related chronic disease --- policy --- food pricing --- food security --- diet price --- food price --- affordability --- food policy --- nutrition policy --- fiscal policy --- obesity prevention --- non-communicable disease --- monitoring and surveillance --- INFORMAS --- reference budgets --- food insecurity --- cost of a healthy diet --- Food-based dietary guidelines --- food insecurity --- food stress --- food affordability --- food insecurity --- food poverty --- prevalence --- household --- food surveys --- secondary data --- Scotland --- Aboriginal and Torres Strait Islander --- remote --- community store --- fruit and vegetables --- incentive --- subsidy --- food security --- nutrition --- diet --- household food insecurity --- mental health --- sex --- Canadian adults --- food insecurity --- access to food --- social assistance payments --- social security --- Newstart allowance --- food and nutrition security --- research --- values --- co-creation --- trauma-informed --- food insecurity --- hunger --- developed countries --- Sustainable Development Goals --- social determinants --- inequality --- food banks --- food security --- food insecurity --- social assistance --- poverty --- homeless --- nutrition environment --- food stress --- food affordability --- policy --- intervention --- determinants --- food banks --- developed countries

Listing 1 - 7 of 7
Sort by
Narrow your search