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Foundations for Moral Relativism : Second expanded edition

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ISBN: 9782821876101 Language: English
Publisher: Open Book Publishers
Subject: Philosophy
Added to DOAB on : 2019-12-06 13:15:39
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In this new edition of Foundations for Moral Relativism, a distinguished moral philosopher tames a bugbear of current debate about cultural difference. J. David Velleman shows that different communities can indeed be subject to incompatible moralities, because their local mores are rationally binding. At the same time, he explains why the mores of different communities, even when incompatible, are still variations on the same moral themes. The book thus maps out a universe of many moral worlds without, as Velleman puts it, “moral black holes”. The six self-standing chapters discuss such diverse topics as online avatars and virtual worlds, lying in Russian and truth-telling in Quechua, the pleasure of solitude and the fear of absurdity. Accessibly written, Foundations for Moral Relativism presupposes no prior training in philosophy.

Neural circuits underlying emotion and motivation: Insights from optogenetics and pharmacogenetics

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195343 Year: Pages: 172 DOI: 10.3389/978-2-88919-534-3 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2015-12-10 11:59:06
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Application of optogenetic and pharmacogenetic tools to study the neural circuits underlying emotional valence, feeding, arousal and motivated behaviors has provided crucial insights into brain function. Expression of light sensitive proteins into specific neurons and subsequent stimulation by light (optogenetics) to control neuronal activity or expression of designer receptors exclusively activated by designer drugs (DREADD) in specific neuronal populations with subsequent activation or suppression of neuronal activity by an otherwise inert ligand (pharmacogenetics) provides control over defined elements of neural circuits. These novel tools have provided a more in depth understanding into several questions about brain function. These include: • Regulation of sleep-wake transition by the interaction of hypocretin neurons of lateral hypothalamus and nor adrenergic neurons of the locus coruleaus • Regulation of feeding by AGRP and POMC neurons in arcuate nucleus of the hypothalamus • Place preference and positive reinforcement by activation of DA neuron of VTA • Place aversion by activation of VTA GABA and lateral habenula neurons • Opposing influences on reinforcement by activation of D1 and D2 expressing medium spiny neurons of dorsal striatum and nucleus accumbens The list still grows... From cell type specific manipulations to signaling properties in the cell (Dietz et al 2012) with unprecedented temporal resolution, these tools revolutionize the exploration of pathways/connectivity. Recent years also witnessed the extension of applying these tools from studying emotional valence and motivated behavior to reactivation of memory. c-fos based genetic approaches allowed us to integrate light sensitive opsins or DREADD receptor into specific neurons that are activated by certain learning events (for example fear) (Garner et al 2012; Liu et al 2012). In this Research Topic, we welcome researchers to contribute original research articles, review articles, methods and commentary on topics utilizing optogenetic and pharmacogenetic tools to study the neural circuits underlying emotional valence, motivation, reinforcement and memory. We believe the Research Topic will shine light on various questions we have about brain function by using novel optogenetic and pharmacogenetic tools and will hopefully inspire ongoing research to overcome the hurdles of using these tools to advance clinical applications.

Emotions in History – Lost and Found

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ISBN: 9786155053344 9786155225031 Year: Language: English
Publisher: Central European University Press
Subject: History
Added to DOAB on : 2015-05-19 15:18:48
License: OpenEdition licence for Books

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Coming to terms with emotions and how they influence human behaviour, seems to be of the utmost importance to societies that are obsessed with everything “neuro.” On the other hand, emotions have become an object of constant individual and social manipulation since “emotional intelligence” emerged as a buzzword of our times. Reflecting on this burgeoning interest in human emotions makes one think of how this interest developed and what fuelled it. From a historian’s point of view, it can be t...

Cultures, Citizenship and Human Rights

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Book Series: Routledge Advances in Sociology ISBN: 9780429198588 9780367185619 Year: Pages: 268 Language: English
Publisher: Taylor & Francis
Subject: Social Sciences
Added to DOAB on : 2019-11-29 11:21:04
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"In Cultures, Citizenship and Human Rights the combined analytical efforts of the fields of human rights law, conflict studies, anthropology, history, media studies, gender studies, and critical race and postcolonial studies raise a comprehensive understanding of the discursive and visual mediation of migration and manifestations of belonging and citizenship. 

More insight into the convergence, but also the tensions between the cultural and the legal foundations of citizenship, has proven to be vital to the understanding of societies past and present, especially to assess processes of inclusion and exclusion. Citizenship is more than a collection of rights and privileges held by the individual members of a state, but involves cultural and historical interpretations, legal contestation and regulation as well as an active engagement with national, regional and local state and other institutions about the boundaries of those (implicitly gendered and raced) rights and privileges. 

Highlighting and assessing the transformations of what citizenship entails today is crucially important to the future of Europe, which both as an idea and as a practical project faces challenges that range from the crisis of legitimacy to the problems posed by mass migration. Many of the issues addressed in this book however also play out in other parts of the world, as several of the chapters reflect. "

Nutrition in Inflammatory Bowel Disease (IBD)

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ISBN: 9783039214396 / 9783039214402 Year: Pages: 370 DOI: 10.3390/books978-3-03921-440-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2019-12-09 11:49:15
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The purpose of this Special Issue “Nutrition in Inflammatory Bowel Disease (IBD)” is to increase knowledge regarding the role of dietary composition and effects in IBD, describing the prevalence of malnutrition in IBD and the effect on clinical outcomes, discussing methods of nutrition risk screening and assessment in IBD, and reviewing mechanisms through which diet and dietary components may affect disease severity. The articles focus on the following areas: Dietary Composition/Therapy Interventions in Ulcerative Colitis and effects on outcomes; Dietary Composition/Therapy Interventions in Crohn’s Disease and effects on outcomes; Nutrition Risk Screening and Assessment in IBD; Mechanisms of Diet in the pathogenesis of IBD.

Keywords

body composition --- obesity --- visceral adipose tissue --- fat --- osteoporosis --- osteopenia --- sarcopenia --- inflammatory bowel disease --- Crohn’s disease --- dietary intake --- malnutrition --- Mediterranean diet --- exclusive enteral nutrition --- children --- IBD --- remission --- mucosal cytokines --- dietary protein level --- colitis --- epithelial repair --- mucosa-adherent microbiota --- intestinal inflammation --- inflammatory bowel disease --- epithelial adherens junctions --- bioactive peptides --- synbiotic --- prebiotic --- probiotic --- IBD --- Bacillus spores --- dietary fibre --- sugar cane fibre --- ulcerative colitis --- colon --- high-sulfur foods --- inflammation --- metagenomics --- microbiota --- sulfur reducing --- inflammatory bowel disease --- Crohn --- ulcerative colitis --- diet --- nutrition --- exclusive enteral nutrition --- intestinal epithelial cells --- inflammation --- probiotics --- Lactobacillus acidophilus --- Bifidobacterium animalis subsp. lactis --- vitamin D --- IBD --- Crohn’s disease --- ulcerative colitis --- supplementation --- deficiency --- Inflammatory Bowel Disease (IBD) --- Mediterranean Diet --- Western-style Diet (WSD) --- Nutritional Approach --- vitamin D --- Crohn’s disease --- ulcerative colitis --- faecal calprotectin --- C-reactive protein --- diet --- inflammatory bowel disease --- microbiota --- intestinal barrier --- nutrients --- immunity --- colitis --- food additive --- diet --- emulsifiers --- high salt diet --- inflammatory bowel diseases --- inflammatory bowel disease --- dietary modification --- exclusive enteral nutrition --- lifestyle modification --- Mediterranean diet --- colorectal cancer --- inflammatory bowel disease --- colorectal cancer --- dysplasia --- berries --- chemoprevention --- Inflammatory Bowel Disease --- micronutrients --- vitamin --- mineral --- deficiency --- inflammatory bowel disease --- dietary habits --- food components --- gut microbiota --- immune homeostasis --- epigenetic changes --- inflammatory bowel disease --- malnutrition --- Mediterranean diet --- older age --- diet --- inflammatory bowel disease --- ulcerative colitis --- inflammatory bowel disease --- Westernisation --- genotypes --- nutrient deficiency --- food intolerance --- FODMAPs --- gluten --- fructose --- lactose --- brassica --- mushrooms --- n/a

The Role of Pregnancy Nutrition in Maternal and Offspring Health

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ISBN: 9783039219964 / 9783039219971 Year: Pages: 320 DOI: 10.3390/books978-3-03921-997-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2020-01-07 09:08:26
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In pregnancy, maternal nutrition sustains and nourishes the developing child. Imbalances in either the direction of nutritional excess or deficiency can have adverse consequences for child health. In addition, more research now suggests that good pregnancy nutrition influences child health beyond pregnancy and delivery. This includes modifying the risk of child health outcomes as they enter childhood and adulthood through influences on placental development, hormonal pathways, and organ structure and function. Poor pregnancy nutrition may also compromise maternal health during pregnancy, which may have long-term consequences for women’s health. Understanding the biological and social mechanisms operating during pregnancy can help in the design of better clinical and public health interventions. This Special Issue on “The Role of Pregnancy Nutrition in Maternal and Offspring Health” includes etiological and mechanistic studies of pregnancy nutrition with short- and long-term maternal and child health outcomes, including original research, narrative reviews, and systematic reviews and meta-analyses. Together, this body of work provides important insights into the influence of dietary patterns, food groups, and nutrients on pregnancy outcomes, and long-term neurodevelopmental, respiratory, and metabolic health in the children. It also highlights nutritional consequences for specific groups of women, including those with pregnancy complications and eating disorders.

Keywords

Obesity --- chronic kidney disease --- foetal programming --- sirtuin --- choline --- Dlx3 --- placenta --- placental insufficiency --- inflammation --- angiogenesis --- apoptosis --- Iodine --- pregnancy --- birth weight --- Insufficiency --- SGA --- preterm Birth --- nutrition --- diet --- vitamin D --- birthweight --- birth length --- head circumference --- gestational age --- pregnancy outcomes --- vegetarian diets --- vegan diets --- plant-based diets --- nutrition --- pregnancy --- breastfeeding --- human milk --- micronutrients --- fetal development --- fatty fish --- essential fatty acids --- omega-3 --- pregnancy --- birth weight --- foetal growth --- preterm birth --- anorexia nervosa --- bulimia nervosa --- binge eating disorder --- diet --- eating behavior --- eating disorders --- nutrition --- pregnancy --- purging --- asthma --- fortification --- vitamin D --- social experiment --- pregnancy --- lactation --- weaning --- food-related IgG --- food clusters --- non-IgE-mediated food reactions --- maternal nutrition --- Mediterranean diet --- offspring health --- DHA --- gestational diabetes --- preeclampsia --- placental transport --- choline --- pregnancy --- infant nutrition --- brain health --- docosahexaenoic acid --- DHA --- eye function --- ghrelin --- hypothalamic inflammation --- microglia --- nutritional programing --- pregnancy nutrition --- neurodevelopmental disorders --- autism spectrum disorder --- attention deficit disorder with hyperactivity --- developmental origins of health and disease --- systematic review --- meta-analysis --- preterm birth --- preterm labor --- etiology --- nutrition --- DHA --- probiotics --- dietary habits --- maternal nutrition --- gestational diabetes --- food frequency questionnaire --- dietary screening --- lifestyle intervention --- pregnancy --- dietary behaviour --- neonatal outcomes --- birth weight --- large for gestational age (LGA) --- small for gestational age (SGA) --- obesity prevention --- immunomodulators --- maternal nutrition --- pregnancy --- Rhodiola --- Echinacea --- Panax --- Camellia

Dietary Behavior and Physical Activity in Children and Adolescents

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ISBN: 9783039216000 / 9783039216017 Year: Pages: 358 DOI: 10.3390/books978-3-03921-601-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2020-01-07 09:08:26
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In recent years, diet- and lifestyle-related disorders have become a major health threat in Europe and worldwide. The contributions in this monograph include 2 review articles and 19 original contributions from several countries that provide new information on the existing research elucidating important aspects of children’s and adolescents’ nutrition and lifestyle behavior. The data included in this Special Issue are from large epidemiological studies, including several multicenter and multinational studies, as well as datasets from surveillance initiatives. The topics of interest of this Special Issue include the co-occurrence of multiple health behaviors in children, the role of parenting and early feeding practices, dairy consumption in childhood, validity of dietary intake data, dietary supplement use in children, as well as socioeconomic disparities and eating culture. The diverse articles in this Special Issue highlight the complexity and extent to which nutrition and physical activity behaviors may influence different health aspects of children and adolescents. As seen by the various findings and recommendations, not only is more work in this area required but the translation of this work to practice and policy is imperative if we are to address the challenges impacting the nutrition, physical activity, and health of young populations.

Keywords

diet --- inflammation --- children’s-dietary inflammatory index --- body composition --- primary school --- dietary pattern --- principal component analysis --- reduced rank regression --- prevention --- validation study --- dietary assessment methods --- food diary --- cross-classification --- children --- whole diet --- preschool --- DAGIS Study --- diet quality --- PANDiet index --- early childhood --- nutritional adequacy --- nutrient intake quality --- growing up milk --- eating behaviour --- psychological eating style --- negative emotions --- Emotion-Induced Eating Scale --- health behaviour --- BMI --- home food environment --- Healthy Eating Index --- dietary quality --- validation --- psychometric --- consumption behavior --- knowledge --- Melanesian --- Pacific --- physical activity --- sugar-sweetened beverage --- noncommunicable diseases --- weight status --- self-weight perception --- cluster analysis --- energy balance-related behaviors --- physical activity --- sedentary behavior --- screen time --- dietary intake --- overweight --- obesity --- children --- family meals --- food parenting practices --- preschoolers --- nutrition risk --- direct observation --- adolescents --- children --- determinants --- dietary supplements --- food choice --- intervention --- nutrition --- preschool --- child --- parent --- dairy --- calcium --- migration status --- dietary habits --- food frequency questionnaire --- socioeconomic disparities --- adolescents --- pediatric --- overweight --- epidemiological transition --- collaboration --- childhood obesity --- CEBQ --- eating behavior and Ile251Leu --- breakfast --- obesity --- cardiovascular --- health --- BMI --- waist circumference --- cholesterol --- blood pressure --- MyHeARTs --- breastfeeding --- formula milk --- taste preference --- healthy diet adherence --- children --- IDEFICS study --- I.Family --- screen time --- physical activity --- preschool children --- food and beverage consumption --- Physical activity --- exercise --- food intake --- diet --- children --- adolescents --- KiGGS --- children --- mothers --- vegetable intake --- consumption behaviors --- choice --- preferences --- vitamin --- mineral --- dietary supplements --- adolescents --- EsKiMo --- dietary screener --- obesity prevention --- sweet preference --- children --- diet quality --- dietary behavior --- physical activity --- young populations --- surveillance --- epidemiology --- public health

Nutrition and Eye Health

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ISBN: 9783039219902 / 9783039219919 Year: Pages: 242 DOI: 10.3390/books978-3-03921-991-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Science (General)
Added to DOAB on : 2020-01-30 16:39:46
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Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies. Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES. The objective of this Special Issue on ‘Nutrition and Eye Health’ is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES.

Keywords

lutein --- RR-zeaxanthin --- mesozeaxanthin (RS zeaxanthin) --- light damage --- photoreceptor degeneration --- oxidative stress --- endoplasmic reticulum stress --- electroretinography --- advanced glycation end products --- chyrsin --- diabetic retinopathy --- endoplasmic reticulum --- retinal pigment epithelium --- visual cycle --- cataract --- phytoconstituents --- lens --- preclinical models --- drug discovery --- age-related macular degeneration --- gut-retina axis --- gut microbiota --- dietary habits --- micronutrients --- fish oil --- omega-3 polyunsaturated fatty acids --- personalised medicine --- Lactobacillus paracasei KW3110 --- retina --- light --- macrophage --- saffron --- Crocus Sativus L. --- crocin --- crocetin --- supplements --- anti-oxidant --- anti-inflammatory --- AMD --- diabetes --- glaucoma --- retina --- oxidative stress --- inflammation --- microvascular lesions --- neoangiogenesis --- polyphenols --- flavonoids --- carotenoids --- saponins --- rosmarinic acid --- sinapic acid --- lenses --- estrogen-deficient rats --- oxidative stress --- reduced glutathione --- omega-3 --- fatty acid --- diet --- dietary assessment --- clinical survey --- eye disease --- dry eye --- age-related macular degeneration --- food frequency questionnaire --- CODS --- clinical practice guidelines --- systematic reviews --- age-related macular degeneration --- nutritional supplements --- diet --- nutrition --- AGREE II --- Cucurbita argyrosperma --- corneal chemical burn --- angiogenesis --- corneal neovascularization (CNV) --- vascular endothelial growth factor (VEGF) --- interleukin-1? (IL-1?) --- cyclooxigenase-2 (COX-2) --- nuclear factor-kappaB (NF-?B) --- dietary antioxidants --- antioxidant supplements --- lens --- cataract --- n/a

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