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Current Progress and Challenges in the Development of a Hepatitis C Virus Vaccine

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889457144 Year: Pages: 128 DOI: 10.3389/978-2-88945-714-4 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Allergy and Immunology
Added to DOAB on : 2019-01-23 14:53:43
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Abstract

More than 70 million people worldwide are infected with hepatitis C virus, a major cause of liver cirrhosis, liver failure and hepatocellular carcinoma world-wide. In the last decade, this cancer has emerged as the second leading cause of cancer death and the global burden is increasing by two million new infections per year, mainly due to injection drug use. An effective vaccine will be the most effective means to contain the spread of this virus worldwide. The articles in this Research Topic describe the progress that has been made towards a preventive vaccine and the challenges that still need to be overcome to ultimately achieve this goal.

Ultrasound Elastography

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ISBN: 9783038979104 / 9783038979111 Year: Pages: 144 DOI: 10.3390/books978-3-03897-911-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-08-28 11:21:27
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The comparison between methods, evaluation of portal hypertension and many other questions are still open issues in liver elastography. New elastographic applications are under evaluation and close to being used in clinical practice. Strain imaging has been incorporated into many disciplines and EFSUMB guidelines are under preparation. More research is necessary for improved evidence for clinical applications in daily practice. The Special Issue published papers on recent advances in development and application of Ultrasound Elastography.

MicroRNA as Biomarkers in Cancer Diagnostics and Therapy

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ISBN: 9783039212491 / 9783039212507 Year: Pages: 166 DOI: 10.3390/books978-3-03921-250-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Microbiology
Added to DOAB on : 2019-08-28 11:21:27
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This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to represent unique microRNA genes in humans, with an increasing number of mechanistic roles identified in developmental, physiological, and pathological processes. Thus, dysregulation of a few key microRNAs can have a profound global effect on the gene expression and molecular programs of a cell. This great potential for clinical intervention has captured the interest and imagination of researchers in many fields. However, very few fields have been as prolific as the field of cancer research. This Special Issue provides but a glimpse of the large body of literature of microRNA biology in cancer research, containing 4 original research studies and 4 review articles that focus on specific hematologic or solid tumors in disease. Collectively, these articles highlight state-of-the-art approaches and methodologies for microRNA detection in tissue, blood, and other body fluids in a range of biomarkers applications, from early cancer detection to prognosis and treatment response. The articles also address some of the challenges regarding clinical implementation.

Refugee, Migrant and Ethnic Minority Health

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ISBN: 9783039216444 / 9783039216451 Year: Pages: 526 DOI: 10.3390/books978-3-03921-645-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-12-09 11:49:15
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International migration, particularly to Europe, has increased in the last few decades, making research on aspects of this phenomenon, including numbers, challenges, and successes, particularly vital. This Special Issue highlights this necessary and relevant area of research. It presents 37 articles including studies on diverse topics relating to the health of refugees and migrants. Most articles (28) present studies focusing on European host countries. The focus on Europe is justified if we take into consideration the increased number of refugees and migrants who have come to Europe in recent years. However, there are also articles which present studies from countries in other continents. The topics discussed in the Issue include healthcare utilization, infectious diseases, mother and child health, mental health, and chronic diseases. Finding from the included articles indicate that further development of guidelines and policies at both local and international levels is needed. Priorities must be set by encouraging and funding in-depth research that aims to evaluate the impact of existing policies and interventions. Such research will help us formulate recommendations for the development of strategies and approaches that improve and strengthen the integration of migrants and refugees into the host countries.

Keywords

breastfeeding --- complementary feeding --- Chinese --- immigrant mothers --- infant --- obesity --- post-traumatic stress disorder (PTSD) --- pain --- pain perception --- understanding of illness --- culture --- family-oriented societies --- refugee and migrant women --- sexual and reproductive health --- training --- knowledge --- confidence --- health care professionals --- emergency care --- triage --- healthcare system strengthening --- migrant health --- North Korean refugees --- depression --- early trauma --- negative automatic thoughts --- path analysis --- ambulance --- economic recession --- emergency medical service --- Greece --- primary healthcare system --- refugee --- triage --- public health --- asylum seeker --- Electronic Health Insurance Card --- refugee --- Germany --- refugee health --- asylum seekers --- migrants --- infectious diseases --- vaccination --- Italy --- refugee and migrant (R&M) health --- refugee crisis --- healthcare --- European Union (EU) --- migrant health --- preparedness --- communicable diseases --- tuberculosis --- LTBI --- refugee --- asylum --- infection --- IGRA --- infectious diseases --- migrant --- asylum seekers --- psychiatric emergency services --- involuntary treatment --- psychiatric hospitalization --- migrants --- sexual health --- help-seeking behavior --- systematic review --- aggression --- emergency department --- workplace violence --- migrants --- failed asylum seekers --- psychiatric emergency services --- psychiatric hospitalisation --- acute stress --- multidimensional intercultural training acculturation model (MITA) --- intercultural competence --- traumatic events --- mental health --- Middle Eastern refugee adolescents --- migration --- health --- infection --- linkage --- care --- sexual and reproductive health --- adolescent --- refugee --- migrant --- young women --- knowledge --- access --- experiences --- systematic review --- Africa --- obesity --- immigration --- education --- inequalities --- health survey --- refugee --- adolescent --- risk factor --- protective factor --- HIV --- AIDS --- stigma --- refugees --- migrants --- economic crisis --- Greece --- migration --- National Health System --- refugee --- Southeast Europe --- immigrant --- healthcare --- HBV --- CHB --- screening --- vaccination --- refugees --- migrants --- pregnancy --- migration --- refugees --- health care provision --- reception center --- sexual violence --- migrants --- refugees --- asylum seekers --- applicants for international protection --- Europe --- prevalence --- hepatitis C --- screening --- migrants --- viral hepatitis elimination --- European Union --- North African --- immigration --- health care --- emergency department --- disparities --- VPD --- immunisation strategies --- health systems --- refugees --- migrants --- cost effectiveness --- healthcare --- migration --- refugee --- asylum seeker --- medical service --- migrant --- medical care --- doctor --- Europe --- Germany --- fruit --- vegetable --- immigrant --- Portuguese --- health --- refugees women --- HIV --- mental health --- stigma --- discrimination --- access to care --- disease prevention --- public health --- stigma --- refugees --- migrants --- MMR vaccination --- measles --- vaccine hesitancy --- autism --- Rinkeby --- Tensta --- immigrants --- Polish --- religiosity --- lifestyle behavior --- smoking --- alcohol consumption --- physical activity --- overweight --- obesity --- migrant populations --- schistosomiasis/schistosoma --- strongyloidiasis/strongyloides --- screening/diagnosis --- treatment --- public health --- GRADE --- refugee --- health --- migration --- chronic disease --- infectious disease --- n/a

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