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Fraude e plágio na universidade: A urgência de uma cultura de integridade no Ensino Superior *

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Book Series: Investigação ISBN: 9789892611228 Year: Pages: 298 DOI: https://doi.org/10.14195/978-989-26-1123-5 Language: Portuguese
Publisher: Coimbra University Press
Added to DOAB on : 2019-04-23 16:21:06
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This book links to another book also published by IUC aiming to constitute two sides of the same coin. Having a different scope, both result from the same research project centered on the theme of integrity and academic fraud and they balance each other. In this book we gathered some of the texts that supported the interventions made by their authors in the final conference of the research project, which took place at the Faculty of Economics, University of Coimbra on 8 and 9 May 2014. These are authors whose reflections were very important for the design and development of the project. Some of them took the external consultants function and its contribution extends far beyond the reflections they wrote here. This is a highly theoretical work, unlike the other book (which organizes the empirical results achieved under the project, related to academic fraud committed by students in Portugal). Integrity and academic fraud and its variants and dimensions; its causes and consequences; obstacles and solutions inherent to his combat; the actors involved and the contexts of their occurrence are, among others, targets of conceptualization, scrutiny and discussion. Discussion is also expressed by the publication, in a conversational tone, of the debates occurred among the participants over the two days of the symposium.

Declaració sobre ètica i integritat en la docència universitària

Authors: --- ---
Book Series: Col·lecció de Bioètica ISBN: 9788491680765 Year: Pages: 100 Language: Catalan, Spanish, Portuguese, English
Publisher: Publicacions i Edicions de la Universitat de Barcelona
Subject: Education --- Philosophy
Added to DOAB on : 2018-10-15 13:19:51
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En aquest document de l’Observatori de Bioètica i Dret s’analitzen els problemes que acuiten actualment la docència a l’educació superior. Els objectius dels autors són concretar què significa la integritat en la docència a la universitat; quins han de ser els seus continguts fonamentals i quines implicacions comporta; influir en els que prenen decisions en l’àmbit dels sistemes d’educació superior, i repercutir en els mitjans de comunicació i en l’opinió pública a fi d’augmentar la qualitat del debat i promoure la presa de decisions de la ciutadania, lliure i informada, en les polítiques del sistema d’educació superior.

Scientific Integrity

Authors: ---
ISBN: 9789087282301 9789400602182 9789400602199 Year: Pages: 183 Language: English
Publisher: Leiden University Press
Subject: Law --- Science (General)
Added to DOAB on : 2019-10-09 11:21:14
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The growing attention for scientific integrity is part of a wider culture of professionalization and accountability − which appears to signal that integrity is no longer self-evident as a core value of professional conduct. Examples abound. But what is scientific integrity? Why does it matter? What are the issues, and what is at stake? What do we know about the nature and scope of violations of scientific integrity? In this book, Kees Schuyt explores the concept of integrity, describes various cases of fraud and other types of dishonest behaviour in research practice, and offers a reflective and pragmatic framework for handling transgressions against the rules of academic research. Drawing on a wide variety of historical examples, Schuyt looks into matters ranging from the codification of scientific integrity to the difference between misconduct, questionable practices, and honest errors, and the uses and abuses of the notion of plagiarism. Last but not least, he considers how the norms and values of academic research can best be transmitted to students and new generations of researchers.&#xD;

Maintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198207 Year: Pages: 129 DOI: 10.3389/978-2-88919-820-7 Language: English
Publisher: Frontiers Media SA
Subject: Botany --- Science (General)
Added to DOAB on : 2016-01-19 14:05:46
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Environmental stresses and metabolic by-products can severely affect the integrity of genetic information by inducing DNA damage and impairing genome stability. As a consequence, plant growth and productivity are irreversibly compromised. To overcome genotoxic injury, plants have evolved complex strategies relying on a highly efficient repair machinery that responds to sophisticated damage perception/signaling networks. The DNA damage signaling network contains several key components: DNA damage sensors, signal transducers, mediators, and effectors. Most of these components are common to other eukaryotes but some features are unique to the plant kingdom. ATM and ATR are well-conserved members of PIKK family, which amplify and transduce signals to downstream effectors. ATM primarily responds to DNA double strand breaks while ATR responds to various forms of DNA damage. The signals from the activated transducer kinases are transmitted to the downstream cell-cycle regulators, such as CHK1, CHK2, and p53 in many eukaryotes. However, plants have no homologue of CHK1, CHK2 nor p53. The finding of Arabidopsis transcription factor SOG1 that seems functionally but not structurally similar to p53 suggests that plants have developed unique cell cycle regulation mechanism. The double strand break repair, recombination repair, postreplication repair, and lesion bypass, have been investigated in several plants. The DNA double strand break, a most critical damage for organisms are repaired non-homologous end joining (NHEJ) or homologous recombination (HR) pathway. Damage on template DNA makes replication stall, which is processed by translesion synthesis (TLS) or error-free postreplication repair (PPR) pathway. Deletion of the error-prone TLS polymerase reduces mutation frequencies, suggesting PPR maintains the stalled replication fork when TLS is not available. Unveiling the regulation networks among these multiple pathways would be the next challenge to be completed. Some intriguing issues have been disclosed such as the cross-talk between DNA repair, senescence and pathogen response and the involvement of non-coding RNAs in global genome stability. Several studies have highlighted the essential contribution of chromatin remodeling in DNA repair. DNA damage sensing, signaling and repair have been investigated in relation to environmental stresses, seed quality issues, mutation breeding in both model and crop plants and all these studies strengthen the idea that components of the plant response to genotoxic stress might represent tools to improve stress tolerance and field performance. This focus issue gives researchers the opportunity to gather and interact by providing Mini-Reviews, Commentaries, Opinions, Original Research and Method articles which describe the most recent advances and future perspectives in the field of DNA damage sensing, signaling and repair in plants. A comprehensive overview of the current progresses dealing with the genotoxic stress response in plants will be provided looking at cellular and molecular level with multidisciplinary approaches. This will hopefully bring together valuable information for both plant biotechnologists and breeders.

Grappling with the Multifaceted World of the DNA Damage Response

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889450572 Year: Pages: 306 DOI: 10.3389/978-2-88945-057-2 Language: English
Publisher: Frontiers Media SA
Subject: Genetics --- Science (General)
Added to DOAB on : 2017-07-06 13:27:36
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DNA damage is a major threat to genomic integrity and cell survival. It can arise both spontaneously and in response to exogenous agents. DNA damage can attack most parts of the DNA structure, ranging from minor and major chemical modifications, to single-strand breaks (SSBs) and gaps, to full double-strand breaks (DSBs). If DNA injuries are mis-repaired or unrepaired, they may ultimately result in mutations or wider-scale genome aberrations that threaten cell homeostasis. Consequently, the cells elicit an elaborate signalling network, known as DNA damage response (DDR), to detect and repair these cytotoxic lesions. This Research Topic was aimed at comprehensive investigations of basic and novel mechanisms that underlie the DNA damage response in eukaryotes.DNA damage is a major threat to genomic integrity and cell survival. It can arise both spontaneously and in response to exogenous agents. DNA damage can attack most parts of the DNA structure, ranging from minor and major chemical modifications, to single-strand breaks (SSBs) and gaps, to full double-strand breaks (DSBs). If DNA injuries are mis-repaired or unrepaired, they may ultimately result in mutations or wider-scale genome aberrations that threaten cell homeostasis. Consequently, the cells elicit an elaborate signalling network, known as DNA damage response (DDR), to detect and repair these cytotoxic lesions. This Research Topic was aimed at comprehensive investigations of basic and novel mechanisms that underlie the DNA damage response in eukaryotes.

Publishing Addiction Science

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ISBN: 9781911529088 9781911529095 9781911529101 9781911529118 Year: Pages: 406 DOI: 10.5334/bbd Language: English
Publisher: Ubiquity Press
Subject: Biology --- Mathematics --- Medicine (General) --- Social Sciences --- Bibliography
Added to DOAB on : 2017-07-11 11:02:05
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"Publishing Addiction Science is a comprehensive guide for addiction scientists facing the complex process of contributing to scholarly journals. Written by an international group of addiction journal editors and their colleagues, it discusses how to write research articles and systematic reviews, choose a journal, respond to reviewers’ reports, become a reviewer, and resolve the often difficult authorship, ethical and citation issues that arise in addiction science publishing. As a “Guide for the Perplexed,” Publishing Addiction Science helps novice as well as experienced researchers to deal with these challenges. It is suitable for university courses and forms the basis of the training workshops offered by the International Society of Addiction Journal Editors (ISAJE).&#xD;Co-sponsored by ISAJE and the scientific journal Addiction, the third edition of Publishing Addiction Science gives special attention to the challenges faced by researchers from developing and non-English-speaking countries and features new chapters on guidance for clinician-scientists and the growth of infrastructure and career opportunities in addiction science."

Tales of Research Misconduct: A Lacanian Diagnostics of Integrity Challenges in Science Novels

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Book Series: Library of Ethics and Applied Philosophy ISSN: 1387-6678 / 2215-0323 ISBN: 9783319655536 9783319655543 Year: Pages: 263 DOI: https://doi.org/10.1007/978-3-319-65554-3 Language: English
Publisher: Springer
Subject: Philosophy
Added to DOAB on : 2017-11-24 16:09:15
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This monograph contributes to the scientific misconduct debate from an oblique perspective, by analysing seven novels devoted to this issue, namely: Arrowsmith by Sinclair Lewis (1925), The affair by C.P. Snow (1960), Cantor’s Dilemma by Carl Djerassi (1989), Perlmann’s Silence by Pascal Mercier (1995), Intuition by Allegra Goodman (2006), Solar by Ian McEwan (2010) and Derailment by Diederik Stapel (2012). Scientific misconduct, i.e. fabrication, falsification, plagiarism, but also other questionable research practices, have become a focus of concern for academic communities worldwide, but also for managers, funders and publishers of research. The aforementioned novels offer intriguing windows into integrity challenges emerging in contemporary research practices. They are analysed from a continental philosophical perspective, providing a stage where various voices, positions and modes of discourse are mutually exposed to one another, so that they critically address and question one another. They force us to start from the admission that we do not really know what misconduct is. Subsequently, by providing case histories of misconduct, they address integrity challenges not only in terms of individual deviance but also in terms of systemic crisis, due to current transformations in the ways in which knowledge is produced. Rather than functioning as moral vignettes, the author argues that misconduct novels challenge us to reconsider some of the basic conceptual building blocks of integrity discourse.

Research Methods Pedagogy: Engaging Psychology Students in Research Methods and Statistics

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889450107 Year: Pages: 102 DOI: 10.3389/978-2-88945-010-7 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Psychology
Added to DOAB on : 2018-02-27 16:16:44
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Research methods and statistics are central to the development of professional competence and evidence based psychological practice. Furthermore, the ability to interpret and apply research findings contributes to the development of psychological literacy, the primary outcome of an undergraduate education in psychology. Despite this, many psychology students express little interest in, and in some cases an active dislike of, learning research methods and statistics. This ebook brings together current research, innovative evidence-based practice and critical discourse related to engaging psychology students in learning quantitative and qualitative mixed methods research.

Interessekonflikter i forskning

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ISBN: 9788202588175 Year: Pages: 259 DOI: 10.23865/noasp.63 Language: Norwegian
Publisher: Cappelen Damm Akademisk/NOASP (Nordic Open Access Scholarly Publishing)
Subject: Philosophy --- Social Sciences --- Science (General)
Added to DOAB on : 2019-04-05 11:21:04
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"This anthology examines various ethical issues related to conflicts of interest in research and raises fundamental questions about the role of research in society. In recent years, researchers and others have expressed concern on several occasions about how research has been conducted or used for political or economic gain, where outcomes of research have been called into question and accusations of rigging or poor quality have been leveled. “Conflict of interest” is a term from research ethics that can help clarify what is at the core of many of these cases.&#xD;&#xD;Questions posed and explored in this anthology include: What exactly is a conflict of interest within the context of research? Is the ideal of pure, unbiased objectivity even realistic? To what degree can transparency remediate challenges associated with conflicts of interest?&#xD;&#xD;The objective with this collection of chapters is to encourage reflection and discourse about the ethical principles and norms that insure quality and integrity in research. The anthology will be of interest to researchers in particular, and all others concerned with ethics in research."&#xD;

Deciphering serotonin's role in neurodevelopment

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889192762 Year: Pages: 131 DOI: 10.3389/978-2-88919-276-2 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2015-12-03 13:02:24
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One of the most challenging questions in neurobiology to tackle is how the serotonergic system steers neurodevelopment. With the increase in serotonergic anxiolytic and antidepressant drugs, serotonin was thought to signal adversity or to serve as an emotional signal. However, a vast amount of literature is accumulating showing that serotonin rather mediates neuroplasticity and plays a key role in early developmental processes. For instance, selective serotonin reuptake inhibitors (SSRIs), serving as antidepressants, increase neurogenesis and trigger autism-related brain and behavioural changes during embryonic and perinatal exposure. Moreover, serotonin transporter gene variation is associated with alterations in corticolimbic neuroplasticity, autism-related neuroanatomical changes, as well alterations in social behaviour. Hence, the view is emerging that early life changes in serotonin levels influence the developmental course of socio-emotional brain circuits that are relevant for autism and other neurodevelopmental disorders. It is particularly exciting that the effects of embryonic and perinatal SSRI exposure and serotonin transporter gene variation on neurodevelopment seem to overlap to a large extent, at the cellular as well as the behavioural level. Yet, the precise mechanisms by which serotonin mediates neurodevelopment in the normal and ´autistic´ brain is unclear. Whereas serotonin has a placental origin during early gestation, serotonergic neurons develop during midgestation under the control of a cascade of transcription factors determining the fate of mid-hindbrain neurons that together for the Raphe nuclei. These neurons are among the earliest neurons to be generated, and because serotonin is released before any conventional synapses are formed, serotonin is suspected to influence crucial neurodevelopmental processes such as proliferation,migration and network formation. During late gestation they target their final destinations in, for instance, the cortex, where they affect the secretion of reelin. Reelin is a secreted extracellular matrix glycoprotein that helps to regulate processes of neuronal migration and positioning in the developing cortex by controlling cell–cell interactions. During the late prenatal and early postnatal phase (in rodents) serotonin further shapes the outgrowth of projecting neurons, synaptic connectivity, and the morphology of white fiber tracts. This is under the influence of transient serotonin transporter expression in (thalamo)cortical projections, sensory and prefrontal cortices and the hippocampus, as well as the local expression patterns of 5-HT1A, 5-HT1B and 5-HT3A receptors that each exert their specific roles in neuronal migration, remodeling of axons, and controlling dendritic complexity. There is also evidence that serotonin influences neural activity in locus ceroeleus neurons. Hence, serotonin appears to influence the development of both short- and long-distance connections in the brain. This Research Topic is devoted to studies pinpointing the neurodevelopmental effects of serotonin in relation to prenatal SSRI exposure, serotonin transporter gene variation, and autism/neurodevelopmental disorders, using a wide-variety of cellular and molecular neurobiological techniques like, (epi)genetics, knockout, knockdown, neuroanatomy, physiology, MRI and behaviour in rodents and humans. We especially encouraged attempts to cross-link the neurodevelopmental processes across the fields of prenatal SSRI exposure, serotonin transporter gene variation, and autism/neurodevelopmental disorders, as well as new views on the positive or beneficial effects on serotonin-mediated neurodevelopmental changes.

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