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Magnesium Intake and Human Health

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ISBN: 9783038973348 9783038973355 Year: Pages: 182 DOI: 10.3390/books978-3-03897-335-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Cardiovascular
Added to DOAB on : 2018-11-16 10:43:14
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ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[Magnesium is universally recognized as an essential nutrient for human life and health. Indeed, magnesium plays an important physiologic role in every organ of the human body. Disturbances of Mg homeostasis have been implicated in the pathophysiology of several diseases, and Mg supplementation has been evaluated in numerous large-scale clinical trials. The World Health Organization has listed magnesium as among those essential nutrients that are consumed in suboptimal amounts by the general population. In particular, this occurs in Western ("Westernized") countries, where a modest to mild Mg2+ deficiency is thought to be common. The consequences of suboptimal Mg intake are largely unknown. A deeper understanding of the link between magnesium intake, its systemic homeostasis, and human pathophysiology is therefore much needed. Here, we have invited the experts to contribute original research or review articles that may help elucidate the pathophysiology of Mg and its underlying molecular mechanisms.]

Magnesium in the Central Nervous System

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ISBN: 9780987073051 Year: Pages: 356 DOI: 10.1017/UPO9780987073051 Language: English
Publisher: University of Adelaide Press
Subject: Medicine (General)
Added to DOAB on : 2012-05-15 03:00:19
License: University of Adelaide Press

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Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium in particular remains elusive, largely because intracelluar levls are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism.&#xD;&#xD;There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration.&#xD;&#xD;This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesium’s involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behaviour.&#xD;&#xD;It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesium’s role in biological systems that has inspired the collation of this volume of work.

Biodegradable Metals

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ISBN: 9783038973867 9783038973874 Year: Pages: 200 DOI: 10.3390/books978-3-03897-387-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General) --- Chemical Engineering
Added to DOAB on : 2018-12-06 10:15:09
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The interest in biocompatible and biodegradable metals, such as magnesium, is mainly related to their potential use as structural material for orthopedic and cardiovascular applications where a temporary medical device is required. However, in the case of magnesium, in vivo experiments have clearly shown that the corrosion degradation rate of magnesium and its alloys is too high and, hence, results in producing gas cavities that can promote the danger of gas embolism, tissue separation, and premature loss of mechanical integrity. The aim of this Special Issue on Biodegradable Metals is to explore and introduce innovative strategies to overcome the current limitations of magnesium.

On the diverse bonding situations in nanostructures : an ab initio computational study

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ISBN: 9783866444508 Year: Pages: VIII, 131 p. DOI: 10.5445/KSP/1000013975 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Chemistry (General)
Added to DOAB on : 2019-07-30 20:01:58
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This computational study investigates diverse bonding situations in nanostructures (carbon nanotubes, fullerenes, metal compounds) spanning a broad range of energies. Weak, dispersive interactions and covalent metal-ligand and metal-metal bonding are examined. The results of efficient density functional calculations are compared to those of correlated wavefunction calculations on model systems. This rigorous validation is crucial in evaluating the balance between computational cost and accuracy.

3D Printing of Metals

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ISBN: 9783038425915 9783038425922 Year: Pages: VIII, 156 DOI: 10.3390/books978-3-03842-592-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2017-12-06 12:54:59
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Three-dimensional printing is a futuristic technology capable of transforming the ways in which we make components and devices. It is almost certain that this technique will find its niche in the manufacturing sector in the very near future. In view of the growing importance of 3D printing, this book addresses key issues related to emerging science and technology in this area. Detailed and informative articles are presented in relation to a wide variety of materials, including those based on critical engineering metals such as aluminum, magnesium, titanium and composites. Advances in various techniques, such as electron beam melting and selective laser melting are discussed. Of key importance in the area of materials science is the end properties of the materials following processing. Accordingly, the articles presented critically discuss the effects of microstructural features such as porosity, forming defects and the heat treatment induced effects on the mechanical properties. Applications covered in these articles are targeted at the aerospace, automobile, defense and aerospace sectors. Overall, the information presented in this book is of significant importance for academic and industrial-based researchers who wish to inform themselves regarding this upcoming highly promising manufacturing technique.

Scientific and Engineering Progress on Aluminum-Based Light-Weight Materials: Research Reports from the German Collaborative Research Center 692

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ISBN: 9783038971962 9783038971979 Year: Pages: 196 DOI: 10.3390/books978-3-03897-197-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Engineering
Added to DOAB on : 2018-09-21 10:25:03
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Aluminum-based light-weight materials offer great potential for novel engineering applications, particularly when they are optimized to exhibit high strength and yet provide sufficient reliability. The last decade has thus seen substantial activity in the research fields of high-strength aluminum alloys and aluminum-based composite materials.For twelve years, backed by solid funding from the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG), scientists of the Collaborative Research Center, “High-strength aluminum-based light-weight materials for safety components” (SFB 692) at TU Chemnitz, Germany, have contributed to this research area. Our research efforts have been focused on three main areas: ultrafine-grained aluminum alloys produced by severe plastic deformation; aluminum matrix composites; and aluminum-based composite materials (including material combinations such as magnesium/aluminum or steel/aluminum and the corresponding joining and forming technologies). The framework of SFB 692 has served as a base for numerous scientific collaborations between scientists in the fields of materials science, design engineering, production engineering, mechanics, and even economics—in Chemnitz, and with many well-established international experts around the world.In this Special Issue, we present recent results on high-strength aluminum-based light-weight materials that also provide a broad overview of research activities in SFB 692 and elsewhere.

Material and Process Design for Lightweight Structures

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ISBN: 9783038979586 / 9783038979593 Year: Pages: 162 DOI: 10.3390/books978-3-03897-959-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Materials
Added to DOAB on : 2019-06-26 08:44:06
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The use of lightweight structures across several industries has become inevitable in today’s world given the ever-rising demand for improved fuel economy and resource efficiency. In the automotive industry, composites, reinforced plastics, and lightweight materials, such as aluminum and magnesium are being adopted by many OEMs at increasing rates to reduce vehicle mass and develop efficient new lightweight designs. Automotive weight reduction with high-strength steel is also witnessing major ongoing efforts to design novel damage-controlled forming processes for a new generation of efficient, lightweight steel components. Although great progress has been made over the past decades in understanding the thermomechanical behavior of these materials, their extensive use as lightweight solutions is still limited due to numerous challenges that play a key role in cost competitiveness. Hence, significant research efforts are still required to fully understand the anisotropic material behavior, failure mechanisms, and, most importantly, the interplay between industrial processing, microstructure development, and the resulting properties. This Special Issue reprint book features concise reports on the current status in the field. The topics discussed herein include areas of manufacturing and processing technologies of materials for lightweight applications, innovative microstructure and process design concepts, and advanced characterization techniques combined with modeling of material’s behavior.

Structure and Mechanical Properties of Transition Group Metals, Alloys, and Intermetallic Compounds

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ISBN: 9783039211463 / 9783039211470 Year: Pages: 222 DOI: 10.3390/books978-3-03921-147-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Materials
Added to DOAB on : 2019-08-28 11:21:27
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The aim of this Special Issue is to present the latest theoretical and experimental achievements concerning the mechanisms of microstructural change in metallic materials subject to different processing methods, and their effect on mechanical properties. It is my pleasure to present a series of compelling scientific papers written by scientists from the community of transition group metals, alloys, and intermetallic compounds.

Keywords

metal matrix composites --- laser metal deposition --- Inconel 625 --- additive manufacturing --- laser processing --- metal matrix composites --- Z-pin reinforcement --- delamination --- carbon fiber --- strengthening mechanisms --- severe plastic deformation (SPD) --- cross-channel extrusion (CCE) --- back pressure (BP) --- numerical simulation (FEM) --- physical modeling technique (PMT) --- metal–matrix composites (MMCs) --- carbon fiber --- mechanical properties --- z-pin reinforcement --- laminate --- titanium alloys --- high pressure torsion --- microhardness --- Cu–Ag alloy --- high-pressure torsion --- ultrafine microstructure --- phase dissolution --- microhardness --- friction stir welding --- heat treatment --- AA2519 --- microstructure --- fatigue --- fractography --- AZ91 --- magnesium alloys --- creep --- high pressure die casting --- additive manufacturing --- Ti-6Al-4V --- LENS --- mechanical characterization --- twin roll casting --- magnesium alloy --- calcium --- Mg-Zn-Al-Ca alloy --- texture --- flow curve --- processing map --- honeycomb structure --- additive manufacturing --- laser engineered net shaping --- LENS --- Ti6Al4V alloy --- energy absorption --- dynamic tests --- solidification thermal parameters --- Cu-Al-Ni-Fe bronze alloys --- hardness --- microhardness --- specific intermetallics --- MAX phase --- Ti3SiC2 --- composite --- high energy ball milling --- spark plasma sintering --- structure --- mechanical properties --- deformation behavior --- tribaloy-type alloy --- CoCrMoSi alloy coatings --- T-800 alloy --- Laves phase --- Laser Engineered Net Shaping (LENSTM) --- electron microscopy (in situ SEM) --- delamination --- metal matrix composites (MMCs) --- z-pinning

Benefits of Resveratrol Supplementation

Authors: ---
ISBN: 9783039212750 / 9783039212767 Year: Pages: 260 DOI: 10.3390/books978-3-03921-276-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2019-08-28 11:21:27
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In recent years, great attention has been paid to polyphenols due to their positive effects on health. One of the most widely-studied phenolic compounds is resveratrol. This molecule, which is naturally present in some foods, shows beneficial effects on various physiological and biochemical processes, thus representing a potential tool for the prevention or the treatment of diseases highly prevalent in our society. Several of these beneficial effects have been observed in human beings, but others only in pre-clinical studies so far, and therefore, it is mandatory to continue with the scientific research in this field. Indeed, new knowledge concerning these issues could enable the development of novel functional foods or nutraceuticals, incorporating resveratrol, suitable for preventing or treating diseases such as cancer, cardiovascular diseases, obesity, dislipemia, insulin resistance and diabetes, liver diseases, etc.

Drinking Water Quality and Human Health

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ISBN: 9783038977261 Year: Pages: 374 DOI: 10.3390/books978-3-03897-727-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Sociology --- Social Sciences
Added to DOAB on : 2019-04-05 10:34:31
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The quality of drinking water is paramount for public health. Despite important improvements in the last decades, access to safe drinking water is not universal. The World Health Organization estimates that almost 10% of the population in the world do not have access to improved drinking water sources. Among other diseases, waterborne infections cause diarrhea, which kills nearly one million people every year, mostly children under 5 years of age. On the other hand, chemical pollution is a concern in high-income countries and an increasing problem in low- and middle-income countries. Exposure to chemicals in drinking water may lead to a range of chronic non-communicable diseases (e.g., cancer, cardiovascular disease), adverse reproductive outcomes, and effects on children’s health (e.g., neurodevelopment), among other health effects. Although drinking water quality is regulated and monitored in many countries, increasing knowledge leads to the need for reviewing standards and guidelines on a nearly permanent basis, both for regulated and newly identified contaminants. Drinking water standards are mostly based on animal toxicity data, and more robust epidemiologic studies with accurate exposure assessment are needed. The current risk assessment paradigm dealing mostly with one-by-one chemicals dismisses the potential synergisms or interactions from exposures to mixtures of contaminants, particularly at the low-exposure range. Thus, evidence is needed on exposure and health effects of mixtures of contaminants in drinking water. Finally, water stress and water quality problems are expected to increase in the coming years due to climate change and increasing water demand by population growth, and new evidence is needed to design appropriate adaptation policies.This Special Issue of International Journal of Environmental Research and Public Health (IJERPH) focuses on the current state of knowledge on the links between drinking water quality and human health.

Keywords

Vibrio pathogens --- rural water resources --- public health --- sub-Saharan Africa --- diarrhoeal disease --- HWTS implementation --- water and sanitation --- drinking water guidance --- infant exposure --- chemical risk assessment --- duration extrapolation --- acute gastroenteritis --- risk --- tap water --- time series study --- turbidity --- urban area --- water operation data --- THMs --- cancer --- effect measure modification --- drinking water --- drinking water --- exposure assessment --- sodium --- potassium --- magnesium --- calcium --- spatial variations --- Denmark --- water safety plans --- drinking water quality --- risk management --- impact assessment --- Asia-Pacific region --- diarrhea --- fever --- cough --- Nigeria --- infant health --- drinking water --- inorganic manganese --- health-based guideline --- infants --- pharmaceuticals --- human health --- environment --- drug labels --- screening method --- LTD --- uncertainty factors --- risk assessment --- risk context --- biomonitoring --- dental health --- drinking water --- fluoride --- pharmacokinetic modeling --- waterborne disease outbreak --- simulation study --- health insurance data --- space–time detection --- drinking water --- nitrate --- cancer --- adverse reproductive outcomes --- methemoglobinemia --- thyroid disease --- endogenous nitrosation --- N-nitroso compounds --- E. coli --- monitoring --- drinking water --- water safety plan --- sanitary inspection --- gravity-fed piped water scheme --- risk management --- chlorination by-product --- France --- environmental exposure --- organic matter --- tap water --- trihalomethanes --- private wells --- groundwater --- drinking water --- animal feeding operation --- fecal coliforms --- enterococci --- E. coli --- Maryland --- nitrite --- disinfection by-product --- drinking water distribution systems --- seasonality --- atrazine --- community water system --- low birth weight --- preterm birth --- small for gestational age --- water contamination --- endocrine disruptor --- drinking water --- radioactivity --- annual effective dose --- carcinogenic --- chronic kidney disease --- end-stage renal disease --- water contaminants --- zinc --- ammonia --- chemical oxygen demand --- dissolved oxygen --- arsenic

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