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Animals and Medicine : The Contribution of Animal Experiments to the Control of Disease

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ISBN: 9782821876347 Language: English
Publisher: Open Book Publishers
Subject: Science (General)
Added to DOAB on : 2019-12-06 13:15:39
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Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives - both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine - from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer. This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

Improving outcomes in cerebral palsy with early intervention: new translational approaches

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195121 Year: Pages: 155 DOI: 10.3389/978-2-88919-512-1 Language: English
Publisher: Frontiers Media SA
Subject: Pediatrics --- Medicine (General) --- Neurology
Added to DOAB on : 2015-12-03 13:02:24
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The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life.CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry. CP may be viewed as aberrant plasticity in response to a lesion, indeed, abnormalities in movement are subtle at first but develop subsequently. It is misleading to suppose that developmental mechanisms are self-reparative. The challenge is to understand activitydependent fine tuning of neural circuitry during normal development and to find how to promote desirable plasticity whilst limiting undesirable effects following developmental lesions. However, before proposing interventions, we have to develop our ability to predict the severity of neonatal insults.We solicited a variety of articles, including long and short reviews, original research and opinion pieces, from both basic scientists and clinicians. Likewise we, as editors, have complementary knowledge and experience in this area. Anna Basu is an academic pediatric neurologist and Gavin Clowry is a developmental neuroscientist.

Creating Healthy and Sustainable Buildings

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ISBN: 9783030194123 Year: Pages: 160 DOI: 10.1007/978-3-030-19412-3 Language: English
Publisher: Springer Nature
Subject: Public Health --- Social Sciences --- Architecture
Added to DOAB on : 2020-02-05 11:21:08
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The open access book discusses human health and wellbeing within the context of built environments. It provides a comprehensive overview of relevant sources of literature and user complaints that clearly demonstrate the consequences of lack of attention to health in current building design and planning. Current designing of energy-efficient buildings is mainly focused on looking at energy problems and not on addressing health. Therefore, even green buildings that place environmental aspects above health issues can be uncomfortable and unhealthy, and can lead to public health problems. The authors identify many health risk factors and their parameters, and the interactions among risk factors and building design elements. They point to the need for public health specialists, engineers and planners to come together and review built environments for human wellbeing and environmental sustainability. The authors therefore present a tool for holistic decision-making processes, leading to short- and long-term benefits for people and their environment.

Sekundärnutzung klinischer Daten – Rechtliche Rahmenbedingungen

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ISBN: 9783954661428 9783954663224 Year: Language: German
Publisher: MWV Medizinisch Wissenschaftliche Verlagsgesellschaft Grant: Knowledge Unlatched - 104963
Subject: Internal medicine
Added to DOAB on : 2020-02-15 11:21:04
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Zunehmend greift medizinische Forschung auf Daten aus der Versorgung zurück. Diese ‚Sekundärnutzung‘ von Behandlungsdaten bringt jedoch zahlreiche Rechtsfragen mit sich. Sozial- und Gesundheitsdaten gehören zu den intimsten Informationen über einen Menschen. Mit dem vorliegenden Rechtsgutachten steht erstmals eine detaillierte Übersicht über die spezifischen rechtlichen Rahmenbedingungen für die Sekundärnutzung medizinischer Daten in den einzelnen Bundesländern zur Verfügung, die auch jeweils die unterschiedliche Trägerschaft und Rechtsform der behandelnden Institution berücksichtigt. Die Analyse gibt Forschern und anderen Akteuren im Gesundheitsbereich Orientierung beim rechtskonformen Umgang mit medizinischen Behandlungsdaten. Das Buch enthält darüber hinaus ein ergänzendes Gutachten, das die rechtlichen Rahmenbedingungen für die Sekundärnutzung der über die elektronische Gesundheitskarte nach § 291a SGB V verwalteten Daten darstellt.

Leitfaden zum Datenschutz in medizinischen Forschungsprojekten

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ISBN: 9783954661237 9783954662951 Year: Language: German
Publisher: MWV Medizinisch Wissenschaftliche Verlagsgesellschaft Grant: Knowledge Unlatched - 104962
Subject: Internal medicine
Added to DOAB on : 2020-02-15 11:21:04
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Das Vertrauen von Patienten und Probanden ist eine unverzichtbare Voraussetzung für den Erfolg medizinischer Forschungsprojekte, die ohne die Erhebung, langfristige Speicherung und Analyse von klinischen Daten und Proben nicht durchgeführt werden können. Medizinische Forschung arbeitet heute überwiegend vernetzt in zunehmend größeren Forschungsverbünden. Entsprechend nimmt auch die Bedeutung von Datenschutz und Datensicherheit immer weiter zu. Die TMF hat bereits 2003 erstmals generische Datenschutzkonzepte für medizinische Forschungsverbünde veröffentlicht. Auf dieser Basis konnten zahlreiche Forschungsprojekte ihre Datenschutzkonzepte schneller erarbeiten und abstimmen. Die dabei gewonnenen Erfahrungen sind in die grundlegende Überarbeitung der generischen Konzepte eingeflossen. So trägt das neue Konzept der Vielschichtigkeit medizinischer Forschungsprozesse durch einen modularen Aufbau Rechnung und wurde zudem in einen umfassenden Leitfaden eingebettet.

P5 eHealth: An Agenda for the Health Technologies of the Future

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ISBN: 9783030279943 Year: Pages: 189 DOI: 10.1007/978-3-030-27994-3 Language: English
Publisher: Springer Nature
Subject: Philosophy --- Public Health --- Psychology --- Social Sciences
Added to DOAB on : 2020-02-05 11:21:06
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This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.

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