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Polymer Micelles

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ISBN: 9783038428077 9783038428084 Year: Pages: VIII, 220 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biochemistry
Added to DOAB on : 2018-04-20 15:30:28
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Abstract

Classically, polymer micelles have been defined as aggregates formed by the self-association of amphiphilic polymers due to the hydrophobic interactions between polymer molecules in water. Practical applications of polymer micelles include as carriers in drug delivery systems, as solubilizers, and as associative thickeners. Polymer micelles that do not fall within the classical definition have recently been reported and reflect important developments in synthesis and analysis. For example, hydrophobic interactions are the classic force driving polymer association, whereas recently, micelles have been formed through interactions such as electrostatics, hydrogen bonds, and coordination bonds. Intermolecular association results in the formation of polymer micelles that are similar to micelles formed from low molecular weight surfactants, whereas unimolecular micelles formed by intramolecular association within a single polymer chain have also been reported, as have stimuli-responsive polymer micelles. It is therefore important to constantly update the information available and our knowledge of polymer micelles. This special issue covers synthesis, characterization, solution properties, association behavior, simulation, and the application of polymer micelles and polymer aggregates. The aim of this issue is to expand our knowledge of polymer micelles by gathering together the latest basic and applied information regarding these supramolecular structures.

Designing Hydrogels for Controlled Drug Delivery

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ISBN: 9783039283569 9783039283576 Year: Pages: 162 DOI: 10.3390/books978-3-03928-357-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-04-07 23:07:08
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The aim of this book is to provide an analysis of the main characteristics and applications of hydrogels. Hydrogels are frequently used for manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery systems, and wound dressings. These materials are useful in everyday life, so publicizing them in both academic and pharmaceutical fields is essential.

Smart and Functional Polymers

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ISBN: 9783039215904 9783039215911 Year: Pages: 306 DOI: 10.3390/books978-3-03921-591-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General) --- Inorganic Chemistry
Added to DOAB on : 2019-12-09 11:49:16
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This book is based on the Special Issue of the journal Molecules on “Smart and Functional Polymers”. The collected research and review articles focus on the synthesis and characterization of advanced functional polymers, polymers with specific structures and performances, current improvements in advanced polymer-based materials for various applications, and the opportunities and challenges in the future. The topics cover the emerging synthesis and characterization technology of smart polymers, core?shell structure polymers, stimuli-responsive polymers, anhydrous electrorheological materials fabricated from conducting polymers, reversible polymerization systems, and biomedical polymers for drug delivery and disease theranostics. In summary, this book provides a comprehensive overview of the latest synthesis approaches, representative structures and performances, and various applications of smart and functional polymers. It will serve as a useful reference for all researchers and readers interested in polymer sciences and technologies.

Keywords

amphiphilicity --- phase change --- polyamino acids --- degradability --- fine-tuning --- pH responsive --- poly(methacrylamide)s --- phase transition --- catalyst --- CO2 --- heterogeneous catalysis --- molecular sieve --- polyether imidazole ionic liquid --- Vitamin E --- albumin --- core-shell nanoparticles --- paclitaxel --- multi-drug resistance --- breast cancer --- conducting polymer --- composite --- electrorheological --- smart fluid --- viscoelastic --- controlled polymerization --- reversible polymerization --- sustainable polymers --- pH responsive polymers --- nanomedicine --- tumor imaging --- drug delivery --- polymerization dispersion method --- polyaniline --- polyvinyl alcohol --- glutaraldehyde --- chemical activation --- Glycopolymer --- post-polymerization functionalization --- perfluoroaryl azides --- Staudinger reaction --- castor oil --- biomedical devices --- polyurethanes --- polycaprolactone-diol --- chitosan --- fluoropolymers --- melt-shear organization --- chemical resistance --- solvent responsiveness --- hydrophobicity --- core/shell particles --- emulsion polymerization --- particle processing --- ?-NaYF4 --- rare earth upconversion nanoparticles --- core–shell structure --- hydrogels --- applications --- targeted drug delivery --- drug release --- hydrophobic drug delivery --- clinical translation --- versatile platform --- administration routes --- diverse therapeutic areas --- hearing loss --- saffron --- endophytic exopolysaccharide --- gentamicin --- cochlear hair cell --- polymeric nanoparticles --- stimuli-sensitive polymers --- co-delivery systems --- synergistic effect --- nucleic acid delivery --- chemotherapy --- phenylboronic acid --- gel --- glucose sensitivity --- drug delivery --- diabetes therapy --- amphiphilic copolymer --- hydrolyzable polyurea --- micelle --- controlled drug delivery --- cancer chemotherapy --- polymerization or post-polymerization modification methods --- polymer-based supramolecular chemistry --- stimuli-responsive polymers --- shape memory polymers --- self-healing polymers --- polymers for industrial catalysis --- polymers for water or effluent treatment --- polymers for sensing, separation, and purification --- polymers for fabrication --- renewable polymer materials used for agriculture --- functional polymers used in food science --- polymers for information storage, electronics, and energy conversion --- functional polymers for diagnosis, imaging, drug delivery, and tissue engineering --- polymers with biological activity (e.g., antitumor, antidiabetic, and antimicrobial activity) --- polymer-based medical devices

Drug Delivery Technology Development in Canada

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ISBN: 9783039280049 9783039280056 Year: Pages: 352 DOI: 10.3390/books978-3-03928-005-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-01-07 09:21:22
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Canada continues to have a rich history of ground-breaking research in drug delivery within academic institutions, pharmaceutical industry and the biotechnology community.

Keywords

doxorubicin --- MG63 --- Vitamin D --- DOX-Vit D --- hypoxia-induced chemoresistance --- cisplatin --- polymeric micelle --- EGFR-targeted therapy --- STAT3 --- HIF-1 --- GE11 peptide --- pharmacological Inhibitors of HIF-1 and STAT3 --- combination therapy --- pharmacokinetics --- antibodies --- radiolabeling --- biodistribution --- mouse models --- oral formulation --- amphotericin B --- fungal infections --- parasitic infections --- developing world --- drug delivery --- liposomes --- drug delivery systems --- innovation --- lipid nanoparticles --- Metaplex --- triggered drug release --- liposomes --- ultrasound --- magnetic fields --- radiation --- oral delivery --- biological barriers --- co-delivery --- throughput --- sustained delivery --- phospholipid complex --- rosmarinic acid --- bioaccessibility --- dissolution --- TNO gastrointestinal model --- gastrointestinal simulator --- phytosterols --- tocopherols --- liposomes --- canola oil deodorizer distillate --- model orange juice --- virus --- plant --- bacteriophage --- phage display --- drug discovery --- encapsulation --- drug delivery --- blood-brain barrier --- intra-arterial chemotherapy --- malignant gliomas --- primary central nervous system lymphomas --- transdermal drug delivery --- Canada --- skin --- permeation enhancers --- oral, head and neck squamous cell carcinoma --- targeted therapies --- drug delivery systems --- nanoparticles --- controlled drug delivery --- circadian clock --- chronotherapy --- precision medicine --- cationic gemini surfactant --- melphalan --- inclusion complex --- ROESY NMR spectroscopy --- 3D spheroid --- drug-resistant melanoma --- liposome --- water miscible solvents --- remote loading --- staurosporine --- cancer --- gambogic acid --- loading gradients --- mefloquine --- child friendly formulation --- blood-brain barrier (BBB) --- drug delivery --- transient modulation --- HAV6 cadherin peptide --- adenanthin --- magnetic resonance imaging (MRI) --- medulloblastoma --- drug delivery --- pharmaceutics --- drug development --- formulation and dosage form development --- translational research --- biologicals --- small molecules --- clinical trials --- pharmacokinetics --- medical devices --- route of administration --- nifedipine --- emulsion --- flavonoids --- topical formulation --- quercetin --- photostabilizers

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english (4)


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