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3D Printed Microfluidic Devices

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ISBN: 9783038974673 / 9783038974680 Year: Pages: 211 DOI: 10.3390/books978-3-03897-468-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering
Added to DOAB on : 2019-01-10 09:24:00
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3D printing has revolutionized the microfabrication prototyping workflow over the past few years. With the recent improvements in 3D printing technologies, highly complex microfluidic devices can be fabricated via single-step, rapid, and cost-effective protocols as a promising alternative to the time consuming, costly and sophisticated traditional cleanroom fabrication. Microfluidic devices have enabled a wide range of biochemical and clinical applications, such as cancer screening, micro-physiological system engineering, high-throughput drug testing, and point-of-care diagnostics. Using 3D printing fabrication technologies, alteration of the design features is significantly easier than traditional fabrication, enabling agile iterative design and facilitating rapid prototyping. This can make microfluidic technology more accessible to researchers in various fields and accelerates innovation in the field of microfluidics. Accordingly, this Special Issue seeks to showcase research papers, short communications, and review articles that focus on novel methodological developments in 3D printing and its use for various biochemical and biomedical applications.

Insights and Advancements in Microfluidics

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ISBN: 9783038425168 9783038425175 Year: Pages: VI, 287 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering
Added to DOAB on : 2017-10-02 11:51:06
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Microfluidics has developed rapidly over the past three decades. Relentless diagnostic, medical and chemical applications have been demonstrated in various applications, plateforms and tools. Have microfluidics realized its full potential? Or is it only a leveraging academic tool? In this Special Issue, we focus on both insights and advancements in microfluidics. We invite emerging investigators and pioneers to contribute commentaries, perspectives and insightful reviews on related topics. The various insights from esteemed colleagues will be collated. We will also discuss technological breakthrough of original works in both short communications and full papers. The main idea is to stimulate the community and to provide an unique collection of insightful papers. We will also cover various topics ranging from 3D printing, paper-based microfludics to conventional polymer-based microfluidics which contributes to the technological advancements.

Advances in Microfluidics - New Applications in Biology, Energy, and Materials Sciences

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ISBN: 9789535127857 9789535127864 9789535141471 Year: Pages: 422 DOI: 10.5772/60788 Language: English
Publisher: IntechOpen
Subject: Biotechnology
Added to DOAB on : 2019-10-03 07:51:49

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Increasing innovations and applications make microfluidics a versatile choice for researchers in many disciplines. This book consists of multiple review chapters that aim to cover recent advances and new applications of microfluidics in biology, electronics, energy, and materials sciences. It provides comprehensive views of various aspects of microfluidics ranging from fundamentals of fabrication, flow control, and droplet manipulation to the most recent exploration in emerging areas such as material synthesis, imaging and novel spectroscopy, and marriage with electronics. The chapters have many illustrations showcasing exciting results. This book should be useful for those who are eager to learn more about microfluidics as well as researchers who want to pick up new concepts and developments in this fast-growing field.

Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications

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Book Series: Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik ISSN: 18695183 ISBN: 9783731502975 Year: Volume: 29 Pages: IX, 138 p. DOI: 10.5445/KSP/1000044095 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:58
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A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different fabrication methods were analyzed to determine mass fabrication capabilities. These fabrication methods also allowed the production of fully structured microchannels to tune the fluids behavior within.

Partikeldetektion in mikrofluidischen Systemen

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ISBN: 9783731503644 Year: Pages: XI, 305 p. DOI: 10.5445/KSP/1000046492 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:59
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Analysis of microparticles is an important tool in medicine, biology and chemistry. In order to address future application areas, new systems will be produced by printing technology. In this work new microfluidic particle detection systems which employ planar optics are developed and analyzed. Because the characteristic of these new systems differs greatly from established particle detection systems the signals and statistics are analyzed in depth.

Development of an Electrochemical Biosensor Platform and a Suitable Low-Impedance Surface Modification Strategy

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Book Series: Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik ISSN: 18695183 ISBN: 9783731502722 Year: Volume: 27 Pages: XVIII, 144 p. DOI: 10.5445/KSP/1000043414 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:59
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In this work, a flexible biosensor platform based on impedance spectroscopy and comprising of gold electrodes, polymeric flow cells and a suitable surface modification were developed. Initially, several surface modification techniques described in literature were implemented and optimized for impedimetric biosensors but their individual limitations rendered them unsuitable for this biosensor platform. A novel method based on photobleaching was developed and tested showing satisfactory results.

Konzeption und prototypische Fertigung einer nicht-invasiven mikrofluidischen Plattform für die Elektrophysiologie (NIMEP) zur Zellenanalyse

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Book Series: Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik ISSN: 18695183 ISBN: 9783731503781 Year: Volume: 31 Pages: XVII, 171 p. DOI: 10.5445/KSP/1000046877 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:57
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The most commonly used measurement technique for electrophysiology is the patch clamp technique. While this measurement technique allows the precise investigation of the communication taking place through ion channels, it has some undesirable drawbacks such as the local destruction of the plasma membrane, a low success rate and an elaborate experimental procedure. To avoid these drawbacks, in this work a new non-invasive microfluidic platform for electrophysiological research (NIMEP) was developed with regard to the activity of ion channels. This novel approach is based on the non-invasive measurement of the total current through the cell membrane and provides a possibility for an automated investigation of the individual cells. In addition, the investigated cell can be used for other applications, since the cell remains in an intact state before and after the test.

Micro/Nano Devices for Chemical Analysis

Authors: ---
ISBN: 9783038425342 9783038425359 Year: Pages: X, 218 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemical Engineering
Added to DOAB on : 2017-10-25 13:25:59
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Since the concept of micro total analysis systems (µ-TAS) has been advocated, various kinds of micro/nano devices have been developed by researchers in many fields, such as in chemistry, chemical engineering, mechanical engineering, electric engineering, biology, and medicine, among others. The analytical techniques for small sample volumes, using the micro/nano devices, heavily impacted the fields of biology, medicine and biotechnology, as well as analytical chemistry. Some applications (DNA analysis, point-of-care testing (POCT), etc.) are already commercially available, and various applications will soon be put into practical use.In this Special Issue, we focus on chemical and biochemical analyses (analytical and sensing techniques) using the various types of the micro/nano devices, including micro/nanofluidic devices, paper-based devices, digital microfluidics, and biochip (DNA, protein, cell) arrays. We are also interested in hyphenated devices with other conventional analytical instruments, and the pretreatment devices and components (valve, pump, etc.) for analysis/assay.

Microdevices and Microsystems for Cell Manipulation

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ISBN: 9783038426189 9783038426191 Year: Pages: VII, 171 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Physics (General)
Added to DOAB on : 2017-12-28 13:52:56
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Microfabricated devices and systems capable of micromanipulation are well-suited for the manipulation of cells. These technologies are capable of a variety of functions, including cell trapping, cell sorting, cell culturing, and cell surgery, often at single-cell or sub-cellular resolution. These functionalities are achieved through a variety of mechanisms, including mechanical, electrical, magnetic, optical, and thermal forces. The operations that these microdevices and microsystems enable are relevant to many areas of biomedical research, including tissue engineering, cellular therapeutics, drug discovery, and diagnostics. This Special Issue will highlight recent advances in the field of cellular manipulation. Technologies capable of parallel single-cell manipulation are of special interest.

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