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Computational Modelling of the Steps Involved in Photodynamic Therapy (Book chapter)

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ISBN: 9789535104469 Year: DOI: 10.5772/37654 Language: English
Publisher: InTechOpen Grant: FP7 Ideas: European Research Council - 258990
Subject: Science (General)
Added to DOAB on : 2019-01-17 11:47:59
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Photodynamic therapy (PDT) is a branch of phototherapy that has seen a surge of interest in the last few decades, due to its potential in the treatment of various cancers, infections and&#xD;&#xD;heart disease.(Bonnett, 2000) This chapter aims to give an overview of the various&#xD;&#xD;photochemical steps involved in PDT as a cancer therapy, and in particular the challenges&#xD;&#xD;and insight gained from their theoretical description. After a brief review of PDT in general,&#xD;&#xD;in a biological and chemical context, the photochemical steps involved will be discussed,&#xD;&#xD;detailing the computational techniques required to model these chemical pathways&#xD;&#xD;theoretically. We will detail the methodologies that can currently be applied, as well as their&#xD;&#xD;limitations of use at present, and areas requiring further development.

Numerical Modelling of Industrial Induction (Book chapter)

Book title: Advances in Induction and Microwave Heating of Mineral and Organic Materials

Authors: --- --- --- --- et al.
ISBN: 9789533075228 Year: DOI: 10.5772/13525 Language: English
Publisher: InTechOpen Grant: FP7 Ideas: European Research Council - 205004
Subject: Science (General)
Added to DOAB on : 2019-01-17 11:47:59
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Induction heating is a physical process extensively used in the metallurgical industry for different applications involving metal melting. The main components of an induction heating&#xD;&#xD;system are an induction coil connected to a power-supply providing an alternating electric&#xD;&#xD;current and a conductive workpiece to be heated, placed inside the coil. The alternating&#xD;&#xD;current traversing the coil generates eddy currents in the workpiece and by means of ohmic&#xD;&#xD;losses the workpiece is heated

The Fluid Dynamic Basis for Actuator Disc and Rotor Theories

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ISBN: 9781614998655 9781614998662 Year: Pages: 148 DOI: 10.3233/978-1-61499-866-2-i Language: English
Publisher: IOS Press
Subject: Mechanics --- Physics (General)
Added to DOAB on : 2018-06-20 14:48:14
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The first rotor performance predictions were published by Joukowsky exactly 100 years ago. Although a century of research has expanded the knowledge of rotor aerodynamics enormously, and modern computer power and measurement techniques now enable detailed analyses that were previously out of reach, the concepts proposed by Froude, Betz, Joukowsky and Glauert for modelling a rotor in performance calculations are still in use today, albeit with modifications and expansions.This book is the result of the author's curiosity as to whether a return to these models with a combination of mathematics, dedicated computations and wind tunnel experiments could yield more physical insight and answer some of the old questions still waiting to be resolved. Although most of the work included here has been published previously, the book connects the various topics, linking them in a coherent storyline.This book will be of interest to those working in all branches of rotor aerodynamics – wind turbines, propellers, ship screws and helicopter rotors. It has been written for proficient students and researchers, and reading it will demand a good knowledge of inviscid (fluid) mechanics.Jens Nørkær Sørensen, DTU, Technical University of Denmark: “(…) a great piece of work, which in a consistent way highlights many of the items that the author has worked on through the years. All in all, an impressive contribution to the classical work on propellers/wind turbines.” Peter Schaffarczyk, Kiel University of Applied Sciences, Germany: “(…) a really impressive piece of work!”Carlos Simão Ferreira, Technical University Delft: “This is a timely book for a new generation of rotor aerodynamicists from wind turbines to drones and personal air-vehicles. In a time where fast numerical solutions for aerodynamic design are increasingly available, a clear theoretical and fundamental formulation of the rotor-wake problem will help professionals to evaluate the validity of their design problem. ‘The Fluid Dynamic Basis for Actuator Disc and Rotor Theories’ is a pleasure to read, while the structure, text and figures are just as elegant as the theory presented.”The cover shows ‘The Red Mill’, by Piet Mondriaan, 1911, collection Gemeentemuseum Den Haag. Cover image: © 2018 Mondrian/Holtzman Trust.

Keywords

rotor aerodynamics --- modelling --- Joukowsky --- Froude --- Betz --- Glauert

La modélisation d'accompagnement

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ISBN: 9782759206216 Year: Pages: 384 DOI: 10.35690/978-2-7592-0621-6 Language: French
Publisher: éditions Quae
Subject: Agriculture (General)
Added to DOAB on : 2019-09-13 11:21:04
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"Sustainable development and its expression in terms of participation by local stakeholders in future choices in regions where they live or work have become topical issues. Companion modelling is particularly original among methods to set up participative approaches around the sustainable management of natural renewable resources. The aim of this book is to familiarise the reader with the companion modelling approach, by presenting the scientific posture that is its foundation, its methods and tools and the special place for models. It also explains how to incorporate several decision scales, take power games into account and lastly assess the effects on the people involved in using this approach.&#xD;This work is based on concrete examples taken from 27 cases studied by the researcher group and on educational tools. It is intended for researchers into rural development and renewable resources as well as students and teachers."&#xD;

Designing Adaptive Virtual Worlds

Authors: ---
ISBN: 9783110367669 9783110399219 Year: Pages: 144 DOI: 10.2478/9783110367669 Language: English
Publisher: De Gruyter
Subject: Computer Science
Added to DOAB on : 2014-11-17 10:10:40
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Designing adaptive virtual worlds takes the design of places for education, entertainment, online communities, business, and cultural activities in 3D virtual worlds to a new level. The place metaphor provides a rich source of styles and examples for designing in 3D virtual worlds. This book is one of the first design books in the field showing how those styles can be captured in a design grammar so that unique places can be created through computational agents responding to the changing needs of the people in the virtual world. Applying the techniques introduced in this book has immediate implications on the design of games and functional places in existing virtual world platforms such as Second Life, OpenSim and Active Worlds as well as future virtual worlds in which the boundaries between digital and physical environments blur.

Mathematics for Healthcare

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889455775 Year: Pages: 284 DOI: 10.3389/978-2-88945-577-5 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Physiology
Added to DOAB on : 2019-01-23 14:53:43
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In 1996, and with extraordinary prescience, Panfilov and Holden had highlighted in their seminal book 'Computational Biology of the Heart' that biology was, potentially, the most mathematical of all sciences. Fast-forward 20 years and we have seen an explotion of applications of mathematics in not only biology, but healthcare that has already produced significant breakthroughs not imaginable more than 20 years ago. Great strides have been made in explaining through quantitative methods the underlying mechanisms of human disease, not without considerable ingenuity and effort. Biological mechanisms are bewildering: complex, ever evolving, multi-scale, variable, difficult to fully access and understand. This poses immense challenges to the computational physiology community that, nevertheless, has developed an impressive arsenal of tools and methods in a vertiginous race to combat disease with the tall order of improving human healthcare. Mechanistic models are now contending with the advent of machine learning in healthcare and the hope is that both approaches will be used synergistically since the complexity of human patophysiology and the difficulty of acquiring human datasets will require both, deductive and inductive methods. This Research Topic presents work that is currently at the frontier in computational physiology with a striking range of applications, from diabetes to graft failure and using a multitude of mathematical tools. This collection of articles represents a snapshot in a field that is moving a dizzying speed, bringing understanding of fundamental mechanism and solutions to healthcare problems experienced by healthcare systems all over the world.

View-based textual modelling

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Book Series: The Karlsruhe Series on Software Design and Quality / Ed. by Prof. Dr. Ralf Reussner ISSN: 18670067 ISBN: 9783866446427 Year: Volume: 6 Pages: xxi, 376 p. DOI: 10.5445/KSP/1000022234 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Computer Science
Added to DOAB on : 2019-07-30 20:02:02
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This work introduces the FURCAS approach, a framework for view-based textual modelling. FURCAS includes means that allow software language engineers to define partial and overlapping textual modelling languages. Furthermore, FURCAS provides an incremental update approach that enables modellers to work with multiple views on the same underlying model. The approach is validated against a set of formal requirements, as well as several industrial case studies showing its practical applicability.

Quantitative analysis of neuroanatomy

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197965 Year: Pages: 244 DOI: 10.3389/978-2-88919-796-5 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.

Sensors and Techniques for 3D Object Modeling in Underwater Environments

ISBN: 9783038422228 9783038422235 Year: Pages: XX, 368 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-08-02 16:10:43
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Water covers approximately 71% of the planet’s surface and human activities have been relying on it since remote times. Many traces of these exist under the “zero level” and will continue to exist in the future. Measuring, positioning, and mapping objects under water have experienced very significant modifications, brought about by advances in technology and also by changed requirements, demands for new products, introduction of new tools, and the modification of existing equipment. The exploration, documentation, and recording of underwater environments remains a difficult task, and is sometimes still unsolved. The research, design, and development of techniques and procedures for correctly validating underwater environments are more than ever important.This Special Issue originates from the ISPRS/CIPA Workshop "UNDERWATER 3D RECORDING & MODELING—Experiences in Data Acquisition, Calibration, Orientation, Modelling & Accuracy Assessment” (http://3dom.fbk.eu/files/underwater/index.html) and will accept improved and extended selected papers derived from the workshop’s proceedings, as well as new contributions from international colleagues.We invite you to submit articles on the following topics:Underwater/Multi-media photogrammetryUnderwater platforms (ROV, AUV, robot, etc.)Characterization of underwater passive and active sensorsUnderwater navigation and positioningUnderwater metrology and inspectionsGeometric modeling in multi-media photogrammetryAccuracy requirement and assessment in underwater 3D applicationsRestoration, enhancement and processing of underwater images3D bathymetry techniquesData processing and underwater 3D modelingSensors for marine biology and water pollutionMulti-sensor integration

The Identification of Critical Road Infrastructures - The Case of Baden-Wuerttemberg

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ISBN: 9783866447882 Year: Pages: VIII, 144 p. DOI: 10.5445/KSP/1000025325 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Business and Management
Added to DOAB on : 2016-08-11 12:46:27
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Today's globalised society highly depends on reliable infrastructure systems like transportation and telecommunication. This doctoral dissertation presents a methodology to identify critical road infrastructures. Critical road sections are those whose failure would entail large costs to society. The dissertation also accounts for aspects like multiple road disruptions and probabilities of failure. Baden-Wuerttemberg in Germany serves as a case study area.

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