Search results: Found 53

Listing 1 - 10 of 53 << page
of 6
>>
Sort by
Nucleoside Modifications

ISBN: 9783038423546 9783038423553 Year: Pages: VIII, 214 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Organic Chemistry --- Chemistry (General)
Added to DOAB on : 2017-04-18 12:32:36
License:

Loading...
Export citation

Choose an application

Abstract

This book contains a collection of twelve state-of-the-art, original papers with results from contemporary research in the syntheses and uses of nucleosides and nucleoside analogues, as well as two reviews on contemporary methodology to modify nucleosides.

Novel Biocomposite Engineering and Bio-Applications

Author:
ISBN: 9783038973829 / 9783038973836 Year: Pages: 215 DOI: 10.3390/books978-3-03897-383-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Biotechnology
Added to DOAB on : 2019-01-17 12:18:18
License:

Loading...
Export citation

Choose an application

Abstract

The engineering and utilization of biocomposites is a research field of major scientific and industrial interest worldwide. The biocomposite area is extensive and spans from structured and solid biocomposites (e.g., reinforced bioabsorbable polymers), films (e.g., antimicrobial barriers), to soft biocomposites (e.g., use of alginates, collagen and nanocellulose as components in bioinks for 3D bioprinting). Key aspects in this respect are the appropriate engineering and production of biomaterials, nanofibres, bioplastics, their functionalization enabling intelligent and active materials, processes for effective manufacturing of biocomposites and the corresponding characterization for understanding their properties.The current Special Issue emphasizes the bio-technological engineering of novel biomaterials and biocomposites, considering also important safety aspects in the production and use of bio- and nanomaterials.

Technology, Trust, and Religion

Author:
Book Series: LUP Academic ISBN: 9789087280598 Year: Pages: 320 DOI: 10.24415/9789087280598 Language: English
Publisher: Leiden University Press
Subject: Religion --- Philosophy --- Media and communication
Added to DOAB on : 2011-11-04 00:00:00
License:

Loading...
Export citation

Choose an application

Abstract

What does it mean to be human in a world of technology? What could be the role of religion in responding to the ecological crisis? Should we be concerned about the modification of food, and even of ourselves? Who do we trust to make decisions regarding our common future? What do we use our technology for? These are not questions for experts only. How can the wider public be involved? Do experts and the general public trust each other sufficiently? Or is the public ignorant, in the eyes of the scientists? And are too many engineers narrow minded, according to the general public? The contributors to this timely and necessary volume address expertise, trust and engagement, as we consider our technological condition , religious resources for the ecological crisis , biotechnology , and matters of trust between scientists and the general public. With contributions from leading scholars in the field, including James Miller from Queen's University, Canada and Tony Watling from the University College, London, this book will captivate a range of readers interested in the spirtitual dimension of of our culture and society.

Advances in Marine Chitin and Chitosan

Authors: ---
ISBN: 9783038421306 9783038421290 Year: Pages: XIV, 470 DOI: 10.3390/books978-3-03842-129-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2016-05-20 15:15:59
License:

Loading...
Export citation

Choose an application

Abstract

Recently, biomass-based polymers from renewable resources have received increasing focus owing to the depletion of petroleum resources. Natural polysaccharides such as cellulose,hemicellulose, and starch are among the candidates from natural resources for biomass polysaccharide products including bioplastics. Although several kinds of neutral or anionicpolysaccharides such as chitin, alginic acid, hyaluronic acid, heparin, and chondroitin sulfate exist in nature, natural cationic polysaccharides are quite limited. Chitin is second only tocellulose as the most natural abundant polysaccharide in the world. Chitosan, the product from the N-deacetylatation of chitin, appears to be the only natural cationic polysaccharide.Therefore, chitin and chitosan due to their unique properties are expected to continue to offer a vast number of possible applications for not only chemical or industrial use, but alsobiomedicine. The research history on chitins, one of the most major and abundant natural polysaccharides on earth, started around 1970. Since the 1980s, chitin and chitosan research(including D-glucosamine, N-acetyl-D-glucosamine, and their oligomers) has progressed significantly over several stages in both fundamental research and industrial fields.

Filamentous Bacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889450954 Year: Pages: 154 DOI: 10.3389/978-2-88945-095-4 Language: English
Publisher: Frontiers Media SA
Subject: Microbiology --- Science (General)
Added to DOAB on : 2017-07-06 13:27:36
License:

Loading...
Export citation

Choose an application

Abstract

Filamentous phage (genus Inovirus) infect almost invariably Gram-negative bacteria. They are distinguished from all other bacteriophage not only by morphology, but also by the mode of their assembly, a secretion-like process that does not kill the host. “Classic” Escherichia coli filamentous phage Ff (f1, fd and M13) are used in display technology and bio/nano/technology, whereas filamentous phage in general have been put to use by their bacterial hosts for adaptation to environment, pathogenesis, biofilm formation, horizontal gene transfer and modulating genome stability. Many filamentous phage have a “symbiotic” life style that is often manifested by inability to form plaques, preventing their identification by standard phage-hunting techniques; while the absence or very low sequence conservation between phage infecting different species often complicates their identification through bioinformatics. Nevertheless, the number of discovered filamentous phage is increasing rapidly, along with realization of their significance. “Temperate” filamentous phage whose genomes are integrated into the bacterial chromosome of pathogenic bacteria often modulate virulence of the host. The Vibrio cholerae phage CTXf genome encodes cholera toxin, whereas many filamentous prophage influence virulence without encoding virulence factors. The nature of their effect on the bacterial pathogenicity and overall physiology is the next frontier in understanding intricate relationship between the filamentous phage and their hosts. Phage display has been widely used as a combinatorial technology of choice for discovery of therapeutic antibodies and peptide leads that have been applied in the vaccine design, diagnostics and drug development or targeting over the past thirty years. Virion proteins of filamentous phage are integral membrane proteins prior to assembly; hence they are ideal for display of bacterial surface and secreted proteins. The use of this technology at the scale of microbial community has potential to identify host-interacting proteins of uncultivable or low-represented community members. Recent applications of Ff filamentous phage extend into protein evolution, synthetic biology and nanotechnology. In many applications, phage serves as a monodisperse long-aspect nano-scaffold of well-defined shape. Chemical or chenetic modifications of this scaffold are used to introduce the necessary functionalities, such as fluorescent labels, ligands that target specific proteins, or peptides that promote formation of inorganic or organic nanostructures. We anticipate that the future holds development of new strategies for particle assembly, site-specific multi-functional modifications and improvement of existing modification strategies. These improvements will render the production of filamentous-phage-templated materials safe and affordable, allowing their applications outside of the laboratory.

Regulation of Chemokine- Receptor Interactions and Functions

Author:
ISBN: 9783038427285 9783038427278 Year: Pages: 228 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biochemistry
Added to DOAB on : 2018-03-26 15:44:06
License:

Loading...
Export citation

Choose an application

Abstract

A hallmark of inflammation is the accumulation of leukocytes, which can serve to remove pathogens and necrotic tissue, but may also damage healthy tissue and exacerbate the inflammatory response. Our understanding of leukocyte recruitment in inflammation was revolutionized in the late 1980s by the discovery of chemokines (chemotactic cytokines), a family of small, secreted proteins that induce migration of selective subsets of leukocytes. Shortly afterwards, chemokines were found to exert their functions through the now familiar chemokine receptors, members of the G protein-coupled receptor superfamily. As their physiological and pathological functions were elucidated, chemokine receptors have become popular targets for drug development in inflammatory diseases as well as cancer metastasis and HIV infection. Extensive research has revealed that the functions of chemokines and their receptors are regulated at numerous levels, including: genetic mutations/polymorphisms; control of expression levels; ligand internalization via functional or decoy receptors; intrinsic selectivity of chemokine-receptor binding; hetero- or homo-oligomerization of chemokines or of receptors; alternative signalling pathways; interaction of chemokines with glycosaminoglycans; post-translational modifications; and binding to pathogen-derived inhibitors. This Special Issue of IJMS focused on the natural and pharmacological mechanisms by which the activities of chemokines and their receptors can be regulated.

Marine Polysaccharides Volume 3

Author:
ISBN: 9783038429012 9783038429029 Year: Volume: 3 Pages: X, 564 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-04-24 09:32:36
License:

Loading...
Export citation

Choose an application

Abstract

The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailoring the production of bioactive compounds in a bioreactor. Of particular interest are polysaccharides produced by micro-organisms from extreme marine environments, due to their recognized different biochemistry. Extracellular polysaccharides (EPSs) with unique properties produced by a number of micro-algae are known. The first volume is a collection of papers concerning the identification and characterization of novel marine polysaccharides. It is divided into three chapters; the first two are dedicated to polysaccharides from different marine sources (algae, micro-algae, animals), while the third one gathers information on the isolation, characterization and bioactivity of new EPSs.

Marine Polysaccharides Volume 2

Author:
ISBN: 9783038428992 9783038429005 Year: Volume: 2 Pages: X, 290 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-04-24 09:35:54
License:

Loading...
Export citation

Choose an application

Abstract

The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailoring the production of bioactive compounds in a bioreactor. Of particular interest are polysaccharides produced by micro-organisms from extreme marine environments, due to their recognized different biochemistry. Extracellular polysaccharides (EPSs) with unique properties produced by a number of micro-algae are known. The first volume is a collection of papers concerning the identification and characterization of novel marine polysaccharides. It is divided into three chapters; the first two are dedicated to polysaccharides from different marine sources (algae, micro-algae, animals), while the third one gathers information on the isolation, characterization and bioactivity of new EPSs.

Marine Polysaccharides Volume 1

Author:
ISBN: 9783038428978 9783038428985 Year: Volume: 1 Pages: VIII, 224 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-04-24 09:38:37
License:

Loading...
Export citation

Choose an application

Abstract

The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailoring the production of bioactive compounds in a bioreactor. Of particular interest are polysaccharides produced by micro-organisms from extreme marine environments, due to their recognized different biochemistry. Extracellular polysaccharides (EPSs) with unique properties produced by a number of micro-algae are known. The first volume is a collection of papers concerning the identification and characterization of novel marine polysaccharides. It is divided into three chapters; the first two are dedicated to polysaccharides from different marine sources (algae, micro-algae, animals), while the third one gathers information on the isolation, characterization and bioactivity of new EPSs.

Graphene-Polymer Composites

Author:
ISBN: 9783038970415 9783038970422 Year: Pages: 232 DOI: 10.3390/books978-3-03897-042-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Materials
Added to DOAB on : 2018-09-13 11:10:39
License:

Loading...
Export citation

Choose an application

Abstract

Presenting very high surface-to-volume ratio, relatively simple processability and low cost, graphene and graphene-related materials were soon identified as promising nanofillers for polymer matrixes. Reports have shown notorious property enhancements for graphene-polymer composites (GPC) at very low filler loadings. Uses of GPC in varied fields, such as energy, electronics, catalysis, separation and purification, biomedicine, aerospace, tribology, etc., have been demonstrated and, in some cases, put into industrial practice. However, challenges still exist. Platelet agglomeration within the polymer matrix is often seen to hinder performance improvements. Poor interfacial adhesion between filler and matrix is also a limiting factor in many systems, demanding for tuning the surface chemistry to promote physical or chemical interactions with the polymer chains. The range of routes for fabrication of graphene-related materials, leading to different morphologies, oxidation states, and degrees of platelet exfoliation, have an impact on the final properties of the composites that has not yet been fully addressed. Some argue that the potential of graphene, and its advantages in relation to other nanofillers, has not yet been clearly demonstrated for polymer composites. This Special Issue provides a state of the art view on the different facets of graphene-polymer composite materials, showing that this area of research is thriving and relevant advancements are still to be expected.

Listing 1 - 10 of 53 << page
of 6
>>
Sort by