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Vaccines, Immunotherapy and New Antifungal Therapy Against Fungi: Updates in the New Frontier

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453276 Year: Pages: 183 DOI: 10.3389/978-2-88945-327-6 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Microbiology
Added to DOAB on : 2018-02-27 16:16:45
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Abstract

Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. Also, it is growing the interest over new drugs development as second choice for treatment when traditional chemotherapy fail. This Research Topic will detail the exciting progress in developing vaccines, immunotherapy and new drugs for fungi.

Skin-Related Neglected Tropical Diseases (Skin-NTDs)—A New Challenge

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ISBN: 9783039212538 9783039212545 Year: Pages: 218 DOI: 10.3390/books978-3-03921-254-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Internal medicine
Added to DOAB on : 2019-08-28 11:21:27
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This Special Issue explores the range of clinical manifestations and epidemiology of both skin NTDs and common skin disease in endemic regions, the use of common diagnostic and management pathways, the different technologies that play a role in diagnosis and training, the role of patient involvement at a community level, as well as the assessment of the results of different initiatives in the field.

Keywords

Mycobacterium ulcerans --- animal reservoir --- transmission --- scabies --- Cushing syndrome --- iatrogenic --- topical corticosteroids --- teledermatology --- eHealth --- mHealth --- long range diagnosis --- dermatology --- telepathology --- technology --- skin disease --- podoconiosis --- lymphedema --- neglected tropical diseases --- NTDs --- mental health --- community engagement --- patient involvement --- stigma --- teledermatology --- Africa --- primary health care --- skin diseases --- tele-expertise --- yaws --- Treponema pallidum --- onchodermatitis --- onchocercal skin disease --- onchocerciasis --- ivermectin --- mycetoma --- clinical presentation --- review --- scabies --- neglected tropical diseases --- impetigo --- mass drug administration --- ivermectin --- integration --- neglected tropical diseases --- disease mapping --- mass drug administration --- morbidity management --- skin diseases --- mobile phone application --- NTDs --- dermatology --- mHealth --- leprosy --- leprosy --- leprosy diagnosis --- PCR --- slit skin smears --- point of care test --- skin biopsy --- early diagnosis --- scabies --- outbreak --- drought --- emergency state --- scabies --- diagnosis --- digital handheld microscope --- resource-poor setting --- Amerindian communities --- Amazon lowland --- case management --- integration --- mass drug administration --- neglected tropical diseases --- skin infections --- skin NTDs --- surveillance --- training --- tropical skin diseases --- n/a --- Mite-Gallery Unit (MGU) --- Entodermoscopy (EDS) --- Dry Dermatoscopy (d-DS) --- Wet Dermatoscopy (w-DS) --- Enhanced Dermatoscopy (e-DS) --- subcutaneous mycosis --- actinomycetoma --- eumycetoma --- sporotrichosis Community dermatology

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