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Recém-nascido de alto risco teoria e prática do cuidar

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ISBN: 9788575412374 Year: Pages: 564 DOI: http://dx.doi.org/10.7476/9788575412374 Language: Portuguese
Publisher: SciELO Books - Editora FIOCRUZ
Subject: Pediatrics
Added to DOAB on : 2014-10-15 21:26:36
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Seleção de textos abrangentes e atuais cobrindo tanto as principais patologias e intervenções relativas aos recém-nascidos gravemente enfermos quanto as áreas profissionais ao tema relacionadas. Registra mais de 20 anos de experiência de uma das mais competentes equipes de neonatologia do País - a do Instituto Fernandes Figueira/Fiocruz -, com sua inegável contribuição no campo da saúde da mulher e da criança. Referência fundamental para neonatologistas e para todos os envolvidos na assistência a recém-nascidos de alto risco.

Neonatal and Pediatric Cerebro-Cardiopulmonary Resuscitation

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889456598 Year: Pages: 112 DOI: 10.3389/978-2-88945-659-8 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Pediatrics
Added to DOAB on : 2019-01-23 14:53:43
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Pediatric resuscitation medicine has witnessed significant advances with improved understanding of the pathophysiology of cardiac arrest and resuscitation. Multiple mechanisms of neurological injury have been identified, outlining potential avenues for neuroprotection following cardiac arrest. Resuscitation science exists at multiple levels of analysis, from biomechanics of chest compressions to implementation of best training procedures in real time, from epidemiology of cardiac arrest survival to molecular mechanisms of cellular injury due to ischemia and reperfusion. What next steps in research and in clinical practice will ensure the best possible neurologic outcome among children who survive cardiac arrest? How can we leverage novel technologies in neuroimaging, nanomaterials, drug delivery, biomarker-based risk stratification and next generation sequencing, among others, to resuscitate and to protect the Central Nervous System (CNS)? How can we improve clinical trial design and data analyses to maintain a robust clinical research infrastructure and to ensure validity and applicability? These are just some of the questions will addressed in this Research Topic. Using evidence-based algorithms and public health approaches to disseminate them, the last decade has seen a paradigm shift in pediatric resuscitation with significantly improved survival from pediatric cardiac arrests. However, neurologic outcome in survivors remains far from optimal. High quality CPR is increasingly recognized as a key factor for improving neurologic outcomes. Advanced technologies allow monitoring the quality of CPR and just-in-time feedback to improve the quality of CPR. Further research is needed to evaluate impact of these technologies on neurologic outcome. The recent American Heart Association CPR guidelines emphasis on Circulation-Airway-Breathing (CAB) approach to CPR needs a careful evaluation in children, in whom timely airway and breathing support are as important as circulation. The growing controversy regarding use of epinephrine, and alternative routes of administration of epinephrine during CPR, warrants further evaluation in the setting of pediatric CPR. Improved outcome of hemodynamic goal-directed CPR over standard CPR in animal models of cardiac arrest has initiated interest in physiology-based CPR, especially in the in-hospital cardiac arrest. Basic and applied-science research have become relevant for specific subpopulations of pediatric cardiac arrest victims and circumstances (e.g., ventricular fibrillation, neonates, congenital heart disease, extracorporeal cardiopulmonary resuscitation). Just-in-time and just-in-place simulation training, which have evolved as training strategies to improve quality of CPR, are being evaluated for outcomes. The concept of just-in-time and just-in-place coaching of CPR providers on high quality CPR is a novel concept which has emerged recently and remains unstudied. Whilst there have been significant advances in newborn stabilization over the last decade many questions remain unanswered. These include the role of delayed cord clamping in preterm infants and term newborns requiring resuscitation, the role of sustained inflations as a method of respiratory support and the role of epinephrine and volume administration in neonatal resuscitation. Novel methods of assessment including the use of end tidal CO2 monitoring, respiratory function monitoring and near infrared spectroscopy warrant further evaluation. The use of transitioning animal models that accurately replicate the newborn circulation with patent fetal shunts are emerging but more assessments in these are required to better establish CPR strategies in newborn infants. Newborn resuscitation training programs have resulted in a reduction in neonatal mortality in the developing world, but key questions remain around the frequency of training, team training methods and the role of simulation training. Post resuscitation interventions, in particular therapeutic hypothermia, has resulted in significant improvements in long-term outcome and there is now a growing interest in adjunct therapies, such as use of melatonin, erythropoietin, or other neuroprotective molecules to improve therapeutic benefits of cooling. Therapeutic hypothermia did not provide any higher benefit than normothermia in children following out of hospital cardiac arrest, although three is considerable debate in the community whether 14% probability of observing a similar outcome if the study were repeated a 100 times applies to an individual child in the PICU. Exciting research is occurring in unraveling connection between inflammation, immune dysregulation and neuroinjury. This will further support research on the use of anti-inflammatory agents and immunomodulators for neuroprotection after cardiac arrest and birth asphyxia.

Forty Years of Heel Prick Screening in the Netherlands

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ISBN: 9783038421894 9783038421900 Year: Pages: 114 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-06-01 16:35:30
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This book aims to provide an overview of developments in the heel prick screening programme in the Netherlands in which similarities with the situation elsewhere in the world, where relevant, will be mentioned. In the Netherlands, the preparations for the national screening programme started in 1964. The formal launch of the programme was on September 1, 1974. In 2014, therefore this programme had existed 40 years. The book is structured as follows. Chapter 1 describes how the programme began with one disease and over the years has continued to expand to currently covering 19 disorders. Chapter 2 focuses on the organisation of the screening programme and the agencies that have been involved over the years. Chapter 3 is intended to provide a global view of the programme in its current form. Chapter 4 describes how neonatal screening programmes elsewhere in the world developed and outline their main differences with the Dutch programme. Finally, Chapter 5 contains the summary and conclusions. This chosen structure leads to some aspects being mentioned more than once. The book is intended for a broad audience that is interested in policy making on heel prick screening; hence, scientific depth is limited. Where possible and useful, references to the scientific literature have been included but completeness has not been pursued. The main sources were the archives of the National Steering Committees for Phenylketonuria and Congenital Hypothyroidism (LBCs), supplemented with interviews with the persons listed in Annex 1 and, if available, their personal archives. This is a translation of the book “Veertig Jaar Hielprikscreening in Nederland”, that was published by Prelum Publishers, Houten, the Netherlands with ISBN 978-90-8562-133-1 © 2014 Prelum, Houten; RIVM, Bilthoven; Vumc, Amsterdam.

Mind-Body Medicine in Children and Adolescents

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ISBN: 9783038425281 9783038425298 Year: Pages: VI, 180 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2017-10-27 12:52:41
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The primary goals of this Special Issue are to encourage readers to become more familiar with the range of mind-body therapies and to explore their application in the pediatric clinical setting. The Issue provides background and literature updates on several of the most commonly used mind-body therapies including biofeedback, clinical hypnosis, guided imagery, meditation, and yoga. The emerging technology of immersive virtual reality is also explored. The Special Issue includes a deliberate mix of case studies and practical clinical guidance, with the dual goals of piquing curiosity and providing resources for clinicians interested in pursuing further training.

Neonatal Screening for Critical Congenital Heart Defects

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ISBN: 9783039210480 / 9783039210497 Year: Pages: 98 DOI: 10.3390/books978-3-03921-049-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-06-26 08:44:06
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Critical congenital heart defects (CCHDs) are potentially life-threatening malformations that remain a significant cause of neonatal mortality and morbidity. Failure to diagnose these conditions shortly after birth may result in acute cardiovascular collapse and death. The identification of CCHDs by routine newborn clinical examination is routine in many countries, but consistently misses over a third of cases, and, although antenatal ultrasound screening can be very effective in early diagnosis, the provision and accuracy of ultrasound screening is highly variable. As most CCHDs present with mild cyanosis (hypoxaemia), which is frequently clinically undetectable, pulse oximetry is a rapid, simple, painless method of accurately identifying hypoxaemia, which has gained popularity as a screen for CCHD. This Special Issue of the International Journal of Neonatal Screening, devoted to ""Neonatal Screening for Critical Congenital Heart Defects (CCHDs)"", will consider the evidence for CCHD screening with pulse oximetry, the acceptability and cost-effectiveness of this intervention, the additional non-cardiac conditions which it may also identify, and international experiences of introducing CCHD screening across the globe.

Probiotics and Prebiotics in Pediatrics

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ISBN: 9783038979500 / 9783038979517 Year: Pages: 258 DOI: 10.3390/books978-3-03897-951-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Pediatrics
Added to DOAB on : 2019-06-26 08:44:06
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The goal of this Special Issue, “Probiotics and Prebiotics in Pediatrics”, is to focus on the importance of pediatric nutrition with probiotics and prebiotics to improve gastrointestinal health in newborn, infants, and children.Specifically, the aim is to clarify if probiotics and prebiotics can influence gut microbiota composition and host-interaction favoring human health and preventing diseases.This new information will provide health care professionals with a widespread, clear and update evidence on probiotics and prebiotics and intestinal gut microbiota in pediatric care.

Keywords

acute diarrhea --- children --- Bacillus clausii --- efficacy --- randomized controlled trials --- breast feeding --- formula feeding --- human milk oligosaccharide --- 2?-fucosyllactose --- Lacto-N-neotetraose --- microbiota --- bifidobacteria --- acute gastroenteritis --- children --- Lactobacillus reuteri --- oral rehydration solution --- probiotics --- zinc --- probiotics --- allergy --- infants --- pediatrics --- human milk oligosaccharides --- human milk --- infant formula --- necrotizing enterocolitis --- preterm infant --- preterm infant --- probiotic --- human milk --- probiotic strain --- safety --- fecal microbiota --- protein hydrolyzed formulas --- cow’s milk protein --- tolerance acquisition --- non-IgE mediated allergy --- microbiome --- intestinal microbiota --- microbial programming --- nutritional programming --- allergy --- prevention --- neonatal --- preterm --- breast milk --- oligosaccharides --- diversity --- necrotizing enterocolitis --- sepsis --- growth --- constipation --- prebiotic --- intestinal transit time --- infant --- Bifidobacterium --- Lactobacillus --- probiotics --- asthma --- Childhood Asthma Control Test --- peak expiratory flow rate --- immunoglobulin E --- “Probiotics”[Mesh] --- “Pregnancy”[Mesh] --- “Infant, Newborn”[Mesh] --- Bifidobacterium breve --- probiotics --- paediatrics --- therapeutic microbiology --- celiac disease --- iron deficiency anemia --- gluten-free diet --- inulin --- prebiotics --- iron absorption --- hepcidin --- probiotics --- microbiota --- celiac disease --- gluten free diet --- probiotics --- functional gastrointestinal disorders --- functional abdominal pain disorders --- functional constipation --- infantile colic --- infant --- colic --- lactobacilli --- n/a --- fecal microbiota --- protein hydrolyzed formulas --- cow’s milk protein --- tolerance acquisition --- non-IgE mediated allergy --- n/a

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