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Sensory Nervous System

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ISBN: 9781789233582 9781789233599 Year: Pages: 170 DOI: 10.5772/68128 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 07:51:51

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The sensory nervous system is of critical importance in our daily lives and contributes to our personal well-being and safety as well as communication with others. However, it is only when disease or injury impair its function that we fully appreciate the relevance of our sensory modalities. During the past decades, research of our senses has seen an ever-growing interest in this exciting field of study. This book provides the reader with an overview of the current state-of-the-art of research of our senses and focuses on the most important evidence-based developments in this area. This book addresses both the physiology and pathophysiology of our sensory nervous system ranging from molecular, cellular, and systems to cognitive and behavioral topics. Individual chapters focus on recent advances in specific areas of sensory systems in different model organisms and humans. All chapters represent recent contributions to the rapidly developing field of sensory science.

Neuroimaging and Neuropsychology of Meditation States

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451784 Year: Pages: 145 DOI: 10.3389/978-2-88945-178-4 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2017-08-28 14:01:09
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Neurophysiological and psychological modifications induced by meditation practice have been consistently addressed by neuroscience. Training meditation practice induced plasticity (Barinaga, 2003; Knight, 2004), and as a consequence several benefit for mental and physical health (Davidson & McEwen, 2012), and cognitive performance. One goal of meditation is to achieve the light of consciousness observing with equanimity (the right distance) clouds of the mind wandering. This Frontiers Research Topic brings together studies from groups of authors whose research focus on neuropsychological systems involved in meditation demonstrating how meditation activates and can modify brain areas, cognitive mechanisms and well-being.

Madness and Creativity: Yes, No or Maybe?

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889196708 Year: Pages: 85 DOI: 10.3389/978-2-88919-670-8 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2015-12-04 13:33:42
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The pervasive idea that madness and creativity are intricately linked is one that holds tremendous fascination for both scientists and the general public alike. Although this view was at first largely driven by anecdotal evidence showcasing the manifestation of mental illness in individuals who exhibited extraordinary levels of creativity in various spheres of life, it initiated a strong impetus to empirically investigate the association between mental health and creativity.A variety of approaches (and combinations of approaches) have been adopted to address this association including clinical, personality, psychometric, behavioral, cognitive, historiometric and neuroscientific. Despite the ever accumulating body of evidence over the past six decades investigating this link, what is lacking is a comprehensive overview of the disparate findings from these different approaches that will enable us to address the question of whether there is an empirically founded relationship between creativity and mental illness. And if such a link does exist, what is the nature of this association? The purpose of this Research Topic was to motivate theorists and researchers to answer this question (or at least attempt to do so) given the available evidence thus far. The themes of interest that were open to exploration in view of this topic included:(a) Which mental disorders are positively associated with creativity?(b) Which mental disorders are negatively associated with creativity?(c) The dynamics of information processing biases (positive versus negative) associated with psychiatric and high-risk populations(d) Theories regarding the madness-creativity link(e) Personality-based studies on creativity(f) Creativity, mental illness and the brain(g) Genes and creativity(h) How can studies on neurological populations inform this debate?(i) What are the areas of impact with regard to real world applications and practice?(j) Historical timeline of this question(k) Evolutionary perspectives on the madness-creativity link(l) Methodological problems associated with this field(m) Philosophical issues to bear in mind when investigating this domain(n) The usefulness of the “troubled genius” concept The invitation to contribute was open to all interested academics regardless of whether they were seasoned explorers within this field of study or just beginning to get their feet wet in its murky waters. As a result of adopting this inclusive approach, the contributions showcase a wide variety of perspectives from academic departments and institutions the world over. What is most encouraging is that so many were willing to openly take on the challenge of tackling this difficult question head on. We hope future discussions that follow through as a result of this collective effort will prove to be just as fruitful.

Novel insights in rehabilitation of neglect, 2nd Edition

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889194094 Year: Pages: 269 DOI: 10.3389/978-2-88919-409-4 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2015-12-10 11:59:06
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Hemispatial neglect is the failure to report, respond to, or orient to novel or meaningful stimuli presented in the contralesional visual field. It constitutes one of the most invalidating neurological disorders that can occur after stroke. It is therefore important to treat neglect as adequate as possible and much of the research dedicated to neglect therefore focuses on rehabilitation. In this special topic, you will find 29 articles on the rehabilitation of neglect. This Research Topic has opened new perspectives, and has given us an indication of where the field is going. Although some of the current rehabilitation techniques have proven to be beneficial, there is limited agreement on the most valuable technique or the mechanisms underlying the ameliorating effects.

Application of Nonlinear Analysis to the Study of Complex Systems in Neuroscience and Behavioral Research

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199969 Year: Pages: 271 DOI: 10.3389/978-2-88919-996-9 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-01-19 14:05:46
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Although nonlinear dynamics have been mastered by physicists and mathematicians for a long time (as most physical systems are inherently nonlinear in nature), the recent successful application of nonlinear methods to modeling and predicting several evolutionary, ecological, physiological, and biochemical processes has generated great interest and enthusiasm among researchers in computational neuroscience and cognitive psychology. Additionally, in the last years it has been demonstrated that nonlinear analysis can be successfully used to model not only basic cellular and molecular data but also complex cognitive processes and behavioral interactions. The theoretical features of nonlinear systems (such unstable periodic orbits, period-doubling bifurcations and phase space dynamics) have already been successfully applied by several research groups to analyze the behavior of a variety of neuronal and cognitive processes. Additionally the concept of strange attractors has lead to a new understanding of information processing which considers higher cognitive functions (such as language, attention, memory and decision making) as complex systems emerging from the dynamic interaction between parallel streams of information flowing between highly interconnected neuronal clusters organized in a widely distributed circuit and modulated by key central nodes. Furthermore, the paradigm of self-organization derived from the nonlinear dynamics theory has offered an interesting account of the phenomenon of emergence of new complex cognitive structures from random and non-deterministic patterns, similarly to what has been previously observed in nonlinear studies of fluid dynamics. Finally, the challenges of coupling massive amount of data related to brain function generated from new research fields in experimental neuroscience (such as magnetoencephalography, optogenetics and single-cell intra-operative recordings of neuronal activity) have generated the necessity of new research strategies which incorporate complex pattern analysis as an important feature of their algorithms. Up to now nonlinear dynamics has already been successfully employed to model both basic single and multiple neurons activity (such as single-cell firing patterns, neural networks synchronization, autonomic activity, electroencephalographic measurements, and noise modulation in the cerebellum), as well as higher cognitive functions and complex psychiatric disorders. Similarly, previous experimental studies have suggested that several cognitive functions can be successfully modeled with basis on the transient activity of large-scale brain networks in the presence of noise. Such studies have demonstrated that it is possible to represent typical decision-making paradigms of neuroeconomics by dynamic models governed by ordinary differential equations with a finite number of possibilities at the decision points and basic heuristic rules which incorporate variable degrees of uncertainty. This e-book has include frontline research in computational neuroscience and cognitive psychology involving applications of nonlinear analysis, especially regarding the representation and modeling of complex neural and cognitive systems. Several experts teams around the world have provided frontline theoretical and experimental contributions (as well as reviews, perspectives and commentaries) in the fields of nonlinear modeling of cognitive systems, chaotic dynamics in computational neuroscience, fractal analysis of biological brain data, nonlinear dynamics in neural networks research, nonlinear and fuzzy logics in complex neural systems, nonlinear analysis of psychiatric disorders and dynamic modeling of sensorimotor coordination.

The Reasoning Brain: The Interplay between Cognitive Neuroscience and Theories of Reasoning

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451180 Year: Pages: 178 DOI: 10.3389/978-2-88945-118-0 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2017-07-06 13:27:36
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Despite the centrality of rationality to our identity as a species (let alone the scientific endeavour), and the fact that it has been studied for several millennia, the present state of our knowledge of the mechanisms underlying logical reasoning remains highly fragmented. For example, a recent review concluded that none of the extant (12!) theories provide an adequate account (Khemlani & Johnson- Laird, 2011), while other authors argue that we are on the brink of a paradigm change, where the old binary logic framework will be washed away and replaced by more modern (and correct) probabilistic and Bayesian approaches (see for example Elqayam & Over, 2012; Oaksford & Chater, 2009; Over, 2009). Over the past 15 years neuroscience brain imaging techniques and patient studies have been used to map out the functional neuroanatomy of reasoning processes. The aim of this research topic is to discuss whether this line of research has facilitated, hindered, or has been largely irrelevant for understanding of reasoning processes. The answer is neither obvious nor uncontroversial. We would like to engage both the cognitive and the neuroscience community in this discussion. Some of the questions of interest are: How have the data generated by the patient and neuroimaging studies: • influenced our thinking about modularity of deductive reasoning • impacted the debate between mental logic theory, mental model theory and the dual mechanism accounts • affected our thinking about dual mechanism theories • informed discussion of the relationship between induction and deduction • illuminated the relationship between language, visual spatial processing and reasoning • affected our thinking about the unity of deductive reasoning processes Have any of the cognitive theories of reasoning helped us explain deficits in certain patient populations? Do certain theories do a better job of this than others? Is there any value to localizing cognitive processes and identifying dissociations (for reasoning and other cognitive processes)? What challenges have neuroimaging data raised for cognitive theories of reasoning? How can cognitive theory inform interpretation of patient data or neuroimaging data? How can patient data or neuroimaging data best inform cognitive theory? This list of questions is not exhaustive. Manuscripts addressing other related questions are welcome. We are interested in hearing from skeptics, agnostics and believers, and welcome original research contributions as well as reviews, methods, hypothesis & theory papers that contribute to the discussion of the current state of our knowledge of how neuroscience is (or is not) helping us to deepen our understanding of the mechanisms underlying logical reasoning processes.

Advances in Dementia Research

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ISBN: 9781789855012 9781789855029 Year: Pages: 64 DOI: 10.5772/intechopen.78252 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 07:51:53

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Advances in Dementia Research provides a comprehensive overview of Alzheimer's dementia. This book also represents the association between the components of metabolic syndrome and Alzheimer's disease. Vascular dementia associated with neurodegeneration and cognitive impairments is due to multiple complications of the neurovascular system. This book attempts to explore the recent advancements of enzyme targets for the management of vascular dementia. Furthermore, this book highlights the effectiveness of social recreational programs as an example of a recovery intervention for persons with dementia that focuses on reducing the risk of social isolation associated with dementia. Together the insightful research presented in this book provides valuable information for neuroscientists, researchers, medical professionals, academicians, and upper-level students, as well as for industry professionals.

The frontiers of clinical research on transcranial direct current stimulation (tDCS) in Neuropsychiatry

Authors: --- --- --- --- et al.
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889192878 Year: Pages: 210 DOI: 10.3389/978-2-88919-287-8 Language: English
Publisher: Frontiers Media SA
Subject: Psychiatry --- Medicine (General)
Added to DOAB on : 2015-12-10 11:59:07
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Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation intervention that induces changes in cortical activity and excitability according to the parameters of stimulation. TDCS effects have been reported since the 1800s with the development of the galvanic cell, although more systematic research has been conducted only from 1950-1970 and then from 1998 onwards. At the present time, most tDCS studies have been conducted in healthy volunteers, proving the properties of tDCS as a technique that induces long-lasting, polarity-dependent changes on specific brain areas. In addition, some studies have applied tDCS in selected neuropsychiatric samples, as to investigate its therapeutic effects, obtaining mixed albeit mostly positive results. Using tDCS in clinical practice could bring enormous gains for the treatment of several neuropsychiatric disorders, as tDCS is a portable, non-expensive and straightforward therapy, being therefore a putative candidate as an add-on or substitutive therapy for pharmacological treatments. However, there is still a gap between tDCS basic and clinical research, as it is still unknown whether and how the potent neuromodulatory effects observed after one tDCS session can be carried over for several weeks; therefore proving that tDCS is also a reliable clinical tool. In addition, another gap is observed in tDCS translational research, as results obtained from experimental animal models might not be fully generalizable to neuropsychiatric disorders in humans. Thus, advancing basic and experimental tDCS research as well as tailoring the optimal parameters of stimulation represents the frontiers of tDCS use in neuropsychiatry. In this special edition, our aim is to gather studies that contribute to the proposal of using tDCS for the treatment and investigation of neuropsychiatric disorders. Desired studies include (but are not limited to) the following topics: (1) clinical trials using tDCS as a treatment for neuropsychiatric disorders. (2) original studies investigating optimal parameters for daily tDCS stimulation. (3) safety and tolerability of tDCS, including reports of unexpected and serious adverse effects. (4) comprehensive reviews of putative mechanisms of action of tDCS for neuropsychiatric disorders. (5) translational research, testing different protocols of stimulation in experimental animals. (6) modeling tDCS studies, including studies testing different tDCS devices and montages. (7) studies of cost-efficacy analysis. (8) development of appropriate study designs for tDCS. (9) development of novel employments of tDCS, such as portable, safe devices that allow domestic utilization. (10) development of more precise and focal tDCS devices. To conclude, our ultimate aim is to host studies that contribute to bridge findings from basic and experimental tDCS research with clinical practice, therefore accelerating tDCS use as a novel arsenal for treating neuropsychiatric disorders.

Levodopa-induced Dyskinesias in Parkinson's Disease: Current Knowledge and Future Scenarios

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195459 Year: Pages: 99 DOI: 10.3389/978-2-88919-545-9 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Medicine (General)
Added to DOAB on : 2016-01-19 14:05:46
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This topic aims to pool the most recent advances in the phenomenology and pathophysiology of levodopa-induced dyskinesias. The papers in this eBook have strongly contributed to reduce the gaps in our knowledge of LIDs pathogenesis.

Neuropsychology and Neuropsychiatry of Neurodegenerative Disorders

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197385 Year: Pages: 190 DOI: 10.3389/978-2-88919-738-5 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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This book compiles all articles within the Research Topic "Neuropsychology and neuropsychiatry of neurodegenerative disorders" published in the journal Frontiers in Aging Neuroscience. The call was launched in 2014 and closed in 2015 with 21 articles published. Papers deal on several important topics of neuropsychology -such as language and visuospatial functions- and neuropsychiatry - such us the emotional or motivational spheres - , and the interphase between them. There are also articles on psychometry, brain morphometry, brain connectivity, diagnostic tests and interventional studies. All these articles are focused on neurodegenerative conditions, mostly Alzheimer’s disease and Parkinson’s disease. Interestingly, several articles addressed the early stages of these diseases. All together, this Research Topic provides a rich perspective of the research made today around neuropsychological and neuropsychiatric aspects of neurodegenerative diseases. We hope readers enjoy this collection of articles.

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