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Modulators of hypothalamic-pituitary-gonadal axis for the control of spermatogenesis and sperm quality in vertebrates

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193585 Year: Pages: 159 DOI: 10.3389/978-2-88919-358-5 Language: English
Publisher: Frontiers Media SA
Subject: Internal medicine --- Medicine (General)
Added to DOAB on : 2016-03-10 08:14:32
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Spermatogenesis is a process highly conserved throughout vertebrate species and is mainly under hypothalamic-pituitary control. It occurs in the testis in a stepwise fashion so that committed spermatogonia develop into spermatocytes and enter meiosis to produce round spermatids. These undergo a morphological transformation (spermiogenesis) into mature spermatids (i.e.: spermatozoa), which are differentially released from Sertoli cells (spermiation) depending on the species. In mammals, further transformations are necessary to form mature spermatozoa, suitable for fertilization. Gonadotropins, mainly responsive to gonadotropin-releasing hormone, control spermatogenesis through specific receptors located at the gonadal level. However, besides the endocrine route, the chemical mediators may also act locally in the gonad. Indeed, it is documented that testis physiology, including steroidogenesis and spermatogenesis, does not fully account for traditional endocrine control but an intragonadal network of autocrine and/or paracrine regulators also exists, whose activity, via cell-to-cell communication, regulates germ cell progression and development of qualitatively mature spermatozoa. Of note, a number of testicular modulators, such as gonadotropin releasing hormone, Kiss-peptin, endocannabinoids, has been early isolated in the brain and latest in the gonads. To fully understand precise mechanisms underlying the functional interaction of this intricate network, needless to say, it is crucially required to have detailed information about modulators and target cells. Through synergy between the respective specializations of all the authors, this topic reviewed emerging knowledge about neuroendocrine and local mediators controlling germ cell progression and maturation.

Ethikmanagement im Krankenhaus

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ISBN: 9783954663378 Year: Pages: 187 DOI: 10.32745/9783954663378 Language: German
Publisher: MWV Medizinisch Wissenschaftliche Verlagsgesellschaft
Subject: Medicine (General)
Added to DOAB on : 2020-07-08 00:02:12
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Air Quality Integrated Assessment: A European Perspective

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Book Series: SpringerBriefs in Applied Sciences and Technology ISSN: 2191-530X ISBN: 9783319333489 9783319333496 Year: Pages: 110 DOI: 10.1007/978-3-319-33349-6 Language: English
Publisher: Springer Nature
Subject: Environmental Sciences
Added to DOAB on : 2017-03-02 09:45:26
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This book reports on the results of an extended survey conducted across Europe within the framework of the APPRAISAL FP7 project to determine the extent to which an integrated assessment approach to air quality is being adopted, on the one hand, by regional and local authorities to develop air quality plans and, on the other, by researchers. Following a detailed analysis of the role and structure of the components of an integrated assessment study, the results of the survey are considered from a variety of perspectives. Above all, the book discusses the new light the survey sheds on emission abatement policies and measures planned at regional and local scales, and on their synergies/trade-offs with measures implemented at the national scale. Detailed consideration is given to the currently available modeling methodologies for identifying emission sources, assessing the effectiveness of emission reduction measures, and evaluating the impacts of emission abatement measures on human health. Current strengths and weaknesses revealed by the survey are explored, and the application of an integrated assessment tool in two case studies (in Brussels and Porto) is discussed. The book will appeal to all those interested in the use of integrated assessment in connection with the sources, effects and control of air pollution.

Näkökulmia tilintarkastukseen ja arviointiin

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ISBN: 9789520304386 Year: Pages: 267 DOI: 10.26530/OAPEN_629586 Language: Finnish
Publisher: Tampere University Press
Subject: Economics
Added to DOAB on : 2017-05-24 11:01:33
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This book Näkökulmia tilintarkastukseen ja arviointiin provides original scientific research about various current auditing and evaluation topics. Over the past decade, the field of auditing has seen substantial changes. The topic areas covered in the first chapters reflect established auditing topics such as the role and responsibility of auditors, transfer pricing, the quality of auditing and issues with audit reports. Other chapters address emerging concerns in performance evaluation and auditing. This book will be of value to practitioners, students and academics interested in contemporary aspects of auditing and evaluation.

Methodological Quality of Interventions in Psychology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889452491 Year: Pages: 120 DOI: 10.3389/978-2-88945-249-1 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Psychology
Added to DOAB on : 2018-02-27 16:16:44
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Evaluations of intervention programs seek to present high-quality design, measures and data to assess their merit and worth. While evaluations differ in their purpose, theoretical framework and methodology, their collective aim is to obtain relevant and meaningful information to inform practice, research, and policy. As such, evaluation findings serve to build a body of knowledge on effective approaches to promote designated psychological outcomes, critical to an individual's overall health and well-being. However, as examined in this e-book, methodological weaknesses directly limit the potential of evaluations of intervention programs. As discussed by Chacón-Moscoso and Sanduvete-Chaves, methodological weaknesses can be attributed to how to define and measure methodological quality and the contextual dependency of instruments designed to measure this quality.In response, this e-book provides a collection of studies on methodological approaches to promote the quality of psychological interventions. Specifically, 10 original works published in the Research Topic Methodological Quality of Interventions in Psychology are included. The papers are organized into two chapters. Concretely, Chapter 1 includes studies pertaining to methodological approaches to enhance the quality of psychological intervention, being context independent solutions. Furthermore, Chapter 2 presents original work in different areas (health, education, sport and social welfare) where methodological quality has been better assessed. Collectively, the papers in this e-book serve to expand the awareness of practitioners and researchers interested in psychological interventions of the critical role of methodological quality in this work. This research was funded by the projects 1150096 (Chilean National Fund of Scientific and Technological Development, FONDECYT); and PSI2015-71947-REDT (Spain’s Ministry of Economy and Competitiveness).

Qualitätsmonitor 2019

Authors: --- ---
ISBN: 9783954664030 9783954664344 Year: Language: German
Publisher: MWV Medizinisch Wissenschaftliche Verlagsgesellschaft Grant: Knowledge Unlatched - 103642
Subject: Medicine (General)
Added to DOAB on : 2019-01-15 13:33:12
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Die Qualität der Versorgung, ihre Sicherung, Verbesserung und Incentivierung sind das erklärte Ziel der Krankenhausgesetzgebung der letzten Jahre. Für die Diskussion über Bewertung, Vergütung und Kommunikation von Qualität im medizinischen Versorgungsgeschehen liefert der Qualitätsmonitor 2019 weitere Impulse. Das Werk greift jährlich relevante Themen aus stationärer und sektorenübergreifender Versorgung auf. Die Fachbeiträge gehen dabei der Frage nach, wie sich das Versorgungssystem unter Qualitätsaspekten gestalten lässt und wie Versorgungsqualität transparenter gemacht werden kann. Weiterhin werden Strukturanforderungen einer qualitätsorientierten medizinischen Versorgung diskutiert und die wissenschaftliche Evidenz zur Gestaltung relevanter Versorgungsbereiche zusammengefasst. Eine weitere Sektion zeigt Eckdaten zur Versorgungsstruktur und Qualitätsdaten der deutschen Krankenhäuser. Der Qualitätsmonitor 2019 unterstützt fundiert die Qualitätssicherungsdebatte in Deutschland.

Keywords

Medicine --- quality --- health care --- health system --- germany

Advanced Signaling Support for IP-based Networks

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ISBN: 9783731500377 Year: Pages: XXX, 333 p. DOI: 10.5445/KSP/1000035118 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Computer Science
Added to DOAB on : 2019-07-30 20:02:01
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This work develops a set of advanced signaling concepts for IP-based networks. It proposes a design for secure and authentic signaling and provides QoS signaling support for mobile users. Furthermore, this work develops methods which allow for scalable QoS signaling by realizing QoS-based group communication mechanisms and through aggregation of resource reservations.

Cold Micro Metal Forming

Authors: --- --- --- --- et al.
Book Series: Lecture Notes in Production Engineering ISBN: 9783030112806 Year: Pages: 358 DOI: 10.1007/978-3-030-11280-6 Language: English
Publisher: Springer Nature
Subject: Agriculture (General)
Added to DOAB on : 2020-02-04 11:21:10
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This open access book contains the research report of the Collaborative Research Center “Micro Cold Forming” (SFB 747) of the University of Bremen, Germany. The topical research focus lies on new methods and processes for a mastered mass production of micro parts which are smaller than 1mm (by forming in batch size higher than one million). The target audience primarily comprises research experts and practitioners in production engineering, but the book may also be of interest to graduate students alike.

La transformation des grains

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ISBN: 9782759227846 9782759227853 9782759227839 Year: Pages: 198 DOI: 10.35690/978-2-7592-2784-6 Language: French
Publisher: éditions Quae
Subject: Agriculture (General)
Added to DOAB on : 2020-02-11 11:21:32
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This book covers several aspects of grain processing and complements the book on grain preservation in the same collection. It presents different processing methods, targeting mainly small and medium-sized enterprises as the main players in food processing systems in the South countries.

Keywords

Africa --- food --- cereal --- legume --- quality --- processing technique

Self-Reported Population Health: An International Perspective based on EQ-5D

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ISBN: 9789400775954 9789400775961 Year: Pages: 212 DOI: 10.1007/978-94-007-7596-1 Language: English
Publisher: Springer Nature
Subject: Public Health --- Biotechnology --- Pharmacy and materia medica --- Medicine (General)
Added to DOAB on : 2014-07-25 14:27:36
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The EQ-5D instrument, as a standardized, cross-culturally validated measure of self-assessed health has a hugely important role in understanding population health within and across countries. Over the past two decades a wealth of international population health survey data have been accumulated by the EuroQol Group from research conducted in many countries across four continents. One of the success factors of the EQ-5D instruments has been the easy availability of national or international sets of EQ-5D data, as well as clear explanations and guidance for users. There is an unmet need to produce a comprehensive book that captures up-to-date and expanded information of EQ-5D self-reported health and index values. EQ-5D population norms and cross-country analyses are provided from representative national surveys of 20 countries and additional regional surveys. This book will be a must for those who believe that how people report and value health is very important.

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