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Einkommensumverteilungen in der gesetzlichen Krankenversicherung

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Book Series: Finanzwissenschaftliche Schriften ISBN: 9783820469592 Year: Pages: 254 DOI: 10.3726/b13775 Language: German
Publisher: Peter Lang International Academic Publishing Group
Subject: Economics
Added to DOAB on : 2019-01-15 13:32:32
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In der gesetzlichen Krankenversicherung (GKV) bestehen so vielfältige Umverteilungswirkungen wie sonst bei keinem anderen System unserer sozialen Sicherung. Ihre Grössenordnungen sind allerdings weitgehend unbekannt. Diese zu quantifizieren ist das Hauptziel der Analyse. Darüber hinaus wird untersucht, inwieweit die GKV von ihrer verteilungspolitischen Konzeption her überhaupt in der Lage ist, konsistente Umverteilungsprozesse zu vollziehen. Hiervon ausgehend werden abschliessend Möglichkeiten der Reform geprüft.

Quantitative analysis of neuroanatomy

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197965 Year: Pages: 244 DOI: 10.3389/978-2-88919-796-5 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.

Applications of STEM (Science, Technology, Engineering and Mathematics) Tools in Microbiology of Infectious Diseases

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451838 Year: Pages: 223 DOI: 10.3389/978-2-88945-183-8 Language: English
Publisher: Frontiers Media SA
Subject: Microbiology --- Science (General)
Added to DOAB on : 2017-08-28 14:01:09
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Epidemiology is a discipline intended to systematically investigate, and ideally quantify, disease dynamics in populations (Perez, 2015). Epidemiological assessmentsmay be divided into four large areas, namely, (a) identification and characterization of a pathogen, (b) development of systems for detection of cases, (c) descriptive epidemiology and quantification of disease patterns, and (d) advanced analytical methods to design intervention strategies. Briefly, there is an initial need for understanding the pathogeny of a disease and condition, which may also include experimental studies and development of new models of infection and proliferation under different conditions. Subsequently, such knowledgemay be applied to support the identification of cases, which typically includes the design, evaluation, and validation of diagnostic tests. Diseasemay then be quantified in a population, leading to the identification of patterns and application of molecular characterization techniques to understand disease spread, and ultimately to identify factors preventing or promoting disease. Finally, those factors may be incorporated into advanced quantitative methods and epidemiological models, which are used to design and evaluate strategies aimed at preventing, controlling, or eliminating disease in the population.Recent years have seen a dramatic increase in the application of science, technology, engineering, and mathematical (STEM) tools and approaches intended to enhance such analytical epidemiology process, with the ultimate goal of supporting disease prevention, control, and eradication. This eBook comprises a series of research articles that, through current state-of-the-art scientific knowledge on the application of STEM tools to the microbiology of infectious diseases, demonstrate their usefulness at the various components of an integral epidemiological approach, divided into the four large components of (a) experimental studies, (b) novel diagnostic techniques, (c) epidemiological characterization, and (d) population modeling and intervention.

New Methods for Measuring and Analyzing Segregation

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Book Series: The Springer Series on Demographic Methods and Population Analysis ISSN: 1389-6784 / 2215-1990 ISBN: 9783319413020 9783319413044 Year: Pages: 334 DOI: https://doi.org/10.1007/978-3-319-41304-4 Language: English
Publisher: Springer
Subject: Ecology
Added to DOAB on : 2017-11-24 15:00:25
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This book introduces new methods for measuring and analyzing residential segregation. It begins by placing all popular segregation indices in the “difference of group means” framework wherein index scores can be obtained as simple differences of group means on individual-level residential attainments scored from area racial composition. Drawing on the insight that in this framework index scores are additively determined by individual residential attainments, the book shows that the level of segregation in a given city can be equated to the effect of group membership (e.g., race) on individual residential attainments. This unifies separate research traditions in the field by joining the analysis of segregation at the aggregate level with the analysis of residential attainments for individuals. Next it shows how segregation analysis can be extended by using multivariate attainment models to assess the impact of group membership (i.e., the level of segregation for a city) while including controls for other relevant individual characteristics (e.g., income, education, language, nativity, etc.). It then illustrates how one can use these models to quantitatively assess the extent to which segregation traces to impacts of group membership on residential attainments versus other factors such as group differences in income. The book then shows how micro-level attainment models can be used to study macro-level variation in segregation; specifically, by estimating multi-level models of individual residential attainments to assess how the effect of group membership (i.e., segregation index scores) vary with city characteristics. Finally, the book introduces refined versions of popular indices that are free of the vexing problem of upward bias. This improves the quality of segregation measurement directly at the level of individual cases and expanding the number of cases that can be safely included in empirical studies.

Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino

Authors: --- --- --- --- et al.
Book Series: Phármakon ISBN: 9788868870157 Year: Volume: 1 Pages: 767 DOI: 10.6093/978-88-6887-015-7
Publisher: FedOA - Federico II University Press
Subject: Therapeutics
Added to DOAB on : 2018-06-08 13:11:19
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For thousands of years, pharmacological knowledge coming from natural remedies, has been handed down from generation to generation, without any awareness of the ways in which preparations are made to face diseases. The advent of pharmaceutical chemistry and of the modern drug industry turned that lack of awareness into a scientific knowledge that changed the destiny of the human race. The twenty-eight chapters of this book, are taken from the lectures held by Professor Ettore Novellino every year in his course “Pharmaceutical Chemistry and Toxicology 2”. The first chapters address the basic notions of drugs, homeostasis, pharmacopoeia, and receptor; then, the different pharmaceutical classes are introduced by analyzing their pharmacological and chemical aspects. In particular, the structural study of the interaction between drugs and receptors or biological enzymes gives the fundamentals to connect the chemical and stereochemical properties of a compound family, with the biological activity, a correlation better known as Quantitative Structure-Activity Relationship (QSAR). Several examples of the synthesis of some of the most historically renown drugs, provided at the end of each chapter, integrate the book.

Economic Geography

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Book Series: Routledge Studies in Economic Geography ISBN: 9780203020258 9780415367844 9781138867154 9781134208784 9781134208777 9781134208739 Year: DOI: 10.4324/9780203020258 Language: English
Publisher: Taylor & Francis
Subject: Geography --- Business and Management --- Economics
Added to DOAB on : 2019-11-08 11:21:26
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The impact of economic geography both within and beyond the wider field of geography has been constrained in the past by its own limitations. Drawing together the work of several eminent geographers this superb collection assesses the current state of knowledge in the sub discipline and its future direction. In doing so, the contributors show how economic geographers have offered explanations that affect places and lives in the broader context of the global economy. Offering a discussion of theoretical constructs and methodologies with the purpose to show the need to combine different approaches in understanding spatial (inter) dependencies, contributors also demonstrate the need to engage with multiple audiences, and within this context they proceed to examine how geographers have interfaced with businesses and policy. This excellent collection moves economic geography from a preoccupation with theory towards more rigorous empirical research with greater relevance for public policy. With excellent breadth of coverage, it provides an outstanding introduction to research topics and approaches.

Vertragsmanagement fuer Investitionsprojekte

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Book Series: Bochumer Beitraege zur Unternehmensfuehrung ISBN: 9783631542101 Year: Pages: 273 DOI: 10.3726/b14027 Language: German
Publisher: Peter Lang International Academic Publishing Group
Subject: Sociology --- Business and Management
Added to DOAB on : 2019-01-15 13:32:19
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Projekte als meist einmalige, neuartige sowie langfristige und mit hohen Zahlungen verbundene Vorhaben erfordern ein an den Projekt- und Unternehmungszielen ausgerichtetes Projektmanagement. Ein explizites Vertragsmanagement mit methodischer Unterstützung findet selten statt. Diese Arbeit zeigt ein Konzept auf, welches die in Investitionsprojekten vorliegenden Kooperationsmerkmale in die Vertrags- und Projektplanung des Auftraggebers integriert. Die theoretischen und die Thematik systematisch erweiternden Ansätze werden fortlaufend durch ein Beispiel veranschaulicht. Der Auftraggeber kann durch die weiterentwickelten Planungsmodelle unter Berücksichtigung der vermuteten Präferenzen des Auftragnehmers die Konsequenzen verschiedener Zahlungsvereinbarungen bestimmen und ein aus seiner Sicht optimales Vertragsdesign festlegen.

Separating arsenic oxyanions from natural waters for oxygen isotope analysis

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Book Series: Karlsruher mineralogische und geochemische Hefte : Schriftenreihe des Instituts für Mineralogie und Geochemie ISSN: 16182677 ISBN: 9783731501442 Year: Volume: 40 Pages: XXXVI, 191 p. DOI: 10.5445/KSP/1000037419 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Astronomy (General)
Added to DOAB on : 2019-07-30 20:02:00
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This study has developed a complete procedure for the measurement of oxygen isotopes in arsenic oxyanions in natural waters by using different adsorbents. The experimental results of kinetic exchange of oxygen between AsO43- and water show that the entire exchange procedure happens in a very short time at different pH conditions and temperatures.

Innovations in Quantitative Risk Management

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Book Series: Springer Proceedings in Mathematics & Statistics ISSN: 21941009 ISBN: 9783319091136 9783319091143 Year: Volume: 99 Pages: 438 DOI: 10.1007/978-3-319-09114-3 Language: English
Publisher: Springer
Subject: Business and Management
Added to DOAB on : 2015-07-15 16:03:26
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Quantitative Finance; Game Theory, Economics, Social and Behav. Sciences; Finance/Investment/Banking; Actuarial Sciences

Functional Imaging in living Plants - Cell Biology meets Physiology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889194650 Year: Pages: 114 DOI: 10.3389/978-2-88919-465-0 Language: English
Publisher: Frontiers Media SA
Subject: Botany --- Science (General)
Added to DOAB on : 2016-03-10 08:14:32
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The study of plant cell physiology is currently experiencing a profound transformation. Novel techniques allow dynamic in vivo imaging with subcellular resolution, covering a rapidly growing range of plant cell physiology. Several basic biological questions that have been inaccessible by the traditional combination of biochemical, physiological and cell biological approaches now see major progress. Instead of grinding up tissues, destroying their organisation, or describing cell- and tissue structure, without a measure for its function, novel imaging approaches can provide the critical link between localisation, function and dynamics. Thanks to a fast growing collection of available fluorescent protein variants and sensors, along with innovative new microscopy technologies and quantitative analysis tools, a wide range of plant biology can now be studied in vivo, including cell morphology & migration, protein localization, topology & movement, protein-protein interaction, organelle dynamics, as well as ion, ROS & redox dynamics. Within the cell, genetic targeting of fluorescent protein probes to different organelles and subcellular locations has started to reveal the stringently compartmentalized nature of cell physiology and its sophisticated spatiotemporal regulation in response to environmental stimuli. Most importantly, such cellular processes can be monitored in their natural 3D context, even in complex tissues and organs – a condition not easily met in studies on mammalian cells. Recent new insights into plant cell physiology by functional imaging have been largely driven by technological developments, such as the design of novel sensors, innovative microscopy & imaging techniques and the quantitative analysis of complex image data. Rapid further advances are expected which will require close interdisciplinary interaction of plant biologists with chemists, physicists, mathematicians and computer scientists. High-throughput approaches will become increasingly important, to fill genomic data with ‘life’ on the scale of cell physiology. If the vast body of information generated in the -omics era is to generate actual mechanistic understanding of how the live plant cell works, functional imaging has enormous potential to adopt the role of a versatile standard tool across plant biology and crop breeding. We welcome original research papers, methodological papers, reviews and mini reviews, with particular attention to contributions in which novel imaging techniques enhance our understanding of plant cell physiology and permits to answer questions that cannot be easily addressed with other techniques.

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