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The Tumor Microenvironment of High Grade Serous Ovarian Cancer

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ISBN: 9783038975540 / 9783038975557 Year: Pages: 434 DOI: 10.3390/books978-3-03897-555-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Oncology
Added to DOAB on : 2019-02-06 09:22:42
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The Special Issue on high grade serous ovarian cancer (HGSOC) and the contribution of the tumor microenviroment (TME) consists of reviews contributed by leaders in the OC field. As HGSOC metastases have a highly complex TME, there is an urgent need to better understand the TME in general, its distinct components in particular, and the role of the TME in the context of disease recurrence and development of chemoresistance. The Special Issue incorporates the current understanding of the different parts of thd TME components, including the cancer cells themselves, the cells surrounding the cancer cells or stromal cells, and the cells of the immune system, which are attracted to the site of metastases. In addition to these cells of the TME, the role of various cellular factors made by the cells of the TME are also the subject of the reviews. In addition, reviews in this Special Issue cover the complex relationships between the molecular mechanisms of HGSOC progression, including genomic, epigenomic and transcriptomic changes and changes in the immune cell landscape, as these may provide attractive new molecular targets for HGSOC therapy.

Hybrid Advanced Optimization Methods with Evolutionary Computation Techniques in Energy Forecasting

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ISBN: 9783038972860 9783038972877 Year: Pages: 250 DOI: 10.3390/books978-3-03897-287-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Computer Science
Added to DOAB on : 2018-10-19 11:45:03
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More accurate and precise energy demand forecasts are required when energy decisions are made in a competitive environment. Particularly in the Big Data era, forecasting models are always based on a complex function combination, and energy data are always complicated. Examples include seasonality, cyclicity, fluctuation, dynamic nonlinearity, and so on. These forecasting models have resulted in an over-reliance on the use of informal judgment and higher expenses when lacking the ability to determine data characteristics and patterns. The hybridization of optimization methods and superior evolutionary algorithms can provide important improvements via good parameter determinations in the optimization process, which is of great assistance to actions taken by energy decision-makers.This book aimed to attract researchers with an interest in the research areas described above. Specifically, it sought contributions to the development of any hybrid optimization methods (e.g., quadratic programming techniques, chaotic mapping, fuzzy inference theory, quantum computing, etc.) with advanced algorithms (e.g., genetic algorithms, ant colony optimization, particle swarm optimization algorithm, etc.) that have superior capabilities over the traditional optimization approaches to overcome some embedded drawbacks, and the application of these advanced hybrid approaches to significantly improve forecasting accuracy.

Dynamics Days Latin America and the Caribbean 2018

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ISBN: 9783039215034 / 9783039215041 Year: Pages: 142 DOI: 10.3390/books978-3-03921-504-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Mathematics
Added to DOAB on : 2019-12-09 16:10:12
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This book contains various works presented at the Dynamics Days Latin America and the Caribbean (DDays LAC) 2018. Since its beginnings, a key goal of the DDays LAC has been to promote cross-fertilization of ideas from different areas within nonlinear dynamics. On this occasion, the contributions range from experimental to theoretical research, including (but not limited to) chaos, control theory, synchronization, statistical physics, stochastic processes, complex systems and networks, nonlinear time-series analysis, computational methods, fluid dynamics, nonlinear waves, pattern formation, population dynamics, ecological modeling, neural dynamics, and systems biology. The interested reader will find this book to be a useful reference in identifying ground-breaking problems in Physics, Mathematics, Engineering, and Interdisciplinary Sciences, with innovative models and methods that provide insightful solutions. This book is a must-read for anyone looking for new developments of Applied Mathematics and Physics in connection with complex systems, synchronization, neural dynamics, fluid dynamics, ecological networks, and epidemics.

Selected Papers from the 8th Annual Conference of Energy Economics and Management

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ISBN: 9783039214570 / 9783039214587 Year: Pages: 162 DOI: 10.3390/books978-3-03921-458-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Physics (General)
Added to DOAB on : 2019-12-09 16:10:12
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This collection represents successful invited submissions from the papers presented at the 8th Annual Conference of Energy Economics and Management held in Beijing, China, 22–24 September 2017. With over 500 participants, the conference was co-hosted by the Management Science Department of National Natural Science Foundation of China, the Chinese Society of Energy Economics and Management, and Renmin University of China on the subject area of “Energy Transition of China: Opportunities and Challenges”. The major strategies to transform the energy system of China to a sustainable model include energy/economic structure adjustment, resource conservation, and technology innovation. Accordingly, the conference and its associated publications encourage research to address the major issues faced in supporting the energy transition of China. Papers published in this collection cover the broad spectrum of energy economics issues, including building energy efficiency, industrial energy demand, public policies to promote new energy technologies, power system control technology, emission reduction policies in energy-intensive industries, emission measurements of cities, energy price movement, and the impact of new energy vehicle.

Machine Learning and Embedded Computing in Advanced Driver Assistance Systems (ADAS)

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ISBN: 9783039213757 / 9783039213764 Year: Pages: 344 DOI: 10.3390/books978-3-03921-376-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:15
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This book contains the latest research on machine learning and embedded computing in advanced driver assistance systems (ADAS). It encompasses research in detection, tracking, LiDAR

Keywords

Vehicle-to-X communications --- Intelligent Transport Systems --- VANET --- DSRC --- Geobroadcast --- multi-sensor --- fusion --- deep learning --- LiDAR --- camera --- ADAS --- object tracking --- kernel based MIL algorithm --- Gaussian kernel --- adaptive classifier updating --- perception in challenging conditions --- obstacle detection and classification --- dynamic path-planning algorithms --- joystick --- two-wheeled --- terrestrial vehicle --- path planning --- infinity norm --- p-norm --- kinematic control --- navigation --- actuation systems --- maneuver algorithm --- automated driving --- cooperative systems --- communications --- interface --- automated-manual transition --- driver monitoring --- visual tracking --- discriminative correlation filter bank --- occlusion --- sub-region --- global region --- autonomous vehicles --- driving decision-making model --- the emergency situations --- red light-running behaviors --- ethical and legal factors --- T-S fuzzy neural network --- road lane detection --- map generation --- driving assistance --- autonomous driving --- real-time object detection --- autonomous driving assistance system --- urban object detector --- convolutional neural networks --- machine vision --- biological vision --- deep learning --- convolutional neural network --- Gabor convolution kernel --- recurrent neural network --- enhanced learning --- autonomous vehicle --- crash injury severity prediction --- support vector machine model --- emergency decisions --- relative speed --- total vehicle mass of the front vehicle --- perception in challenging conditions --- obstacle detection and classification --- dynamic path-planning algorithms --- drowsiness detection --- smart band --- electrocardiogram (ECG) --- photoplethysmogram (PPG) --- recurrence plot (RP) --- convolutional neural network (CNN) --- squeeze-and-excitation --- residual learning --- depthwise separable convolution --- blind spot detection --- machine learning --- neural networks --- predictive --- vehicle dynamics --- electric vehicles --- FPGA --- GPU --- parallel architectures --- optimization --- panoramic image dataset --- road scene --- object detection --- deep learning --- convolutional neural network --- driverless --- autopilot --- deep leaning --- object detection --- generative adversarial nets --- image inpainting --- n/a

Integral Transforms and Operational Calculus

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ISBN: 9783039216185 / 9783039216192 Year: Pages: 510 DOI: 10.3390/books978-3-03921-619-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:16
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Researches and investigations involving the theory and applications of integral transforms and operational calculus are remarkably wide-spread in many diverse areas of the mathematical, physical, chemical, engineering and statistical sciences.

Keywords

highly oscillatory --- convolution quadrature rule --- volterra integral equation --- Bessel kernel --- convergence --- higher order Schwarzian derivatives --- Janowski star-like function --- Janowski convex function --- bound on derivatives --- tangent numbers --- tangent polynomials --- Carlitz-type q-tangent numbers --- Carlitz-type q-tangent polynomials --- (p,q)-analogue of tangent numbers and polynomials --- (p,q)-analogue of tangent zeta function --- symmetric identities --- zeros --- Lommel functions --- univalent functions --- starlike functions --- convex functions --- inclusion relationships --- analytic function --- Hankel determinant --- exponential function --- upper bound --- nonlinear boundary value problems --- fractional-order differential equations --- Riemann-Stieltjes functional integral --- Liouville-Caputo fractional derivative --- infinite-point boundary conditions --- advanced and deviated arguments --- existence of at least one solution --- Fredholm integral equation --- Schauder fixed point theorem --- Hölder condition --- generalized Kuramoto–Sivashinsky equation --- modified Kudryashov method --- exact solutions --- Maple graphs --- analytic function --- Hadamard product (convolution) --- partial sum --- Srivastava–Tomovski generalization of Mittag–Leffler function --- subordination --- differential equation --- differential inclusion --- Liouville–Caputo-type fractional derivative --- fractional integral --- existence --- fixed point --- Bernoulli spiral --- Grandi curves --- Chebyshev polynomials --- pseudo-Chebyshev polynomials --- orthogonality property --- symmetric --- encryption --- password --- hash --- cryptography --- PBKDF --- q–Bleimann–Butzer–Hahn operators --- (p,q)-integers --- (p,q)-Bernstein operators --- (p,q)-Bleimann–Butzer–Hahn operators --- modulus of continuity --- rate of approximation --- K-functional --- Hurwitz-Lerch zeta function --- generalized functions --- analytic number theory --- ?-generalized Hurwitz-Lerch zeta functions --- derivative properties --- series representation --- basic hypergeometric functions --- generating functions --- q-polynomials --- analytic functions --- Mittag–Leffler functions --- starlike functions --- convex functions --- Hardy space --- vibrating string equation --- initial conditions --- spectral decomposition --- regular solution --- the uniqueness of the solution --- the existence of a solution --- analytic --- ?-convex function --- starlike function --- strongly-starlike function --- subordination --- q -Sheffer–Appell polynomials --- generating relations --- determinant definition --- recurrence relation --- q -Hermite–Bernoulli polynomials --- q -Hermite–Euler polynomials --- q -Hermite–Genocchi polynomials --- Volterra integral equations --- highly oscillatory Bessel kernel --- Hermite interpolation --- direct Hermite collocation method --- piecewise Hermite collocation method --- differential operator --- q-hypergeometric functions --- meromorphic function --- Mittag–Leffler function --- Hadamard product --- differential subordination --- starlike functions --- Bell numbers --- radius estimate --- (p, q)-integers --- Dunkl analogue --- generating functions --- generalization of exponential function --- Szász operator --- modulus of continuity --- function spaces and their duals --- distributions --- tempered distributions --- Schwartz testing function space --- generalized functions --- distribution space --- wavelet transform of generalized functions --- Fourier transform --- analytic function --- subordination --- Dziok–Srivastava operator --- nonlinear boundary value problem --- nonlocal --- multi-point --- multi-strip --- existence --- Ulam stability --- functions of bounded boundary and bounded radius rotations --- subordination --- functions with positive real part --- uniformly starlike and convex functions --- analytic functions --- univalent functions --- starlike and q-starlike functions --- q-derivative (or q-difference) operator --- sufficient conditions --- distortion theorems --- Janowski functions --- analytic number theory --- ?-generalized Hurwitz–Lerch zeta functions --- derivative properties --- recurrence relations --- integral representations --- Mellin transform --- natural transform --- Adomian decomposition method --- Caputo fractional derivative --- generalized mittag-leffler function --- analytic functions --- Hadamard product --- starlike functions --- q-derivative (or q-difference) operator --- Hankel determinant --- q-starlike functions --- fuzzy volterra integro-differential equations --- fuzzy general linear method --- fuzzy differential equations --- generalized Hukuhara differentiability --- spectrum symmetry --- DCT --- MFCC --- audio features --- anuran calls --- analytic functions --- convex functions --- starlike functions --- strongly convex functions --- strongly starlike functions --- uniformly convex functions --- Struve functions --- truncated-exponential polynomials --- monomiality principle --- generating functions --- Apostol-type polynomials and Apostol-type numbers --- Bernoulli, Euler and Genocchi polynomials --- Bernoulli, Euler, and Genocchi numbers --- operational methods --- summation formulas --- symmetric identities --- Euler numbers and polynomials --- q-Euler numbers and polynomials --- Hurwitz-Euler eta function --- multiple Hurwitz-Euler eta function --- higher order q-Euler numbers and polynomials --- (p, q)-Euler numbers and polynomials of higher order --- symmetric identities --- symmetry of the zero

Emergent Quantum Mechanics. David Bohm Centennial Perspectives

Authors: --- --- ---
ISBN: 9783038976165 Year: Pages: 544 DOI: 10.3390/books978-3-03897-617-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Physics (General) --- Science (General)
Added to DOAB on : 2019-04-05 10:34:31
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Emergent quantum mechanics explores the possibility of an ontology for quantum mechanics. The resurgence of interest in ""deeper-level"" theories for quantum phenomena challenges the standard, textbook interpretation. The book presents expert views that critically evaluate the significance—for 21st century physics—of ontological quantum mechanics, an approach that David Bohm helped pioneer. The possibility of a deterministic quantum theory was first introduced with the original de Broglie-Bohm theory, which has also been developed as Bohmian mechanics. The wide range of perspectives that were contributed to this book on the occasion of David Bohm’s centennial celebration provide ample evidence for the physical consistency of ontological quantum mechanics. The book addresses deeper-level questions such as the following: Is reality intrinsically random or fundamentally interconnected? Is the universe local or nonlocal? Might a radically new conception of reality include a form of quantum causality or quantum ontology? What is the role of the experimenter agent? As the book demonstrates, the advancement of ‘quantum ontology’—as a scientific concept—marks a clear break with classical reality. The search for quantum reality entails unconventional causal structures and non-classical ontology, which can be fully consistent with the known record of quantum observations in the laboratory.

Keywords

quantum foundations --- nonlocality --- retrocausality --- Bell’s theorem --- Bohmian mechanics --- quantum theory --- surrealistic trajectories --- Bell inequality --- quantum mechanics --- generalized Lagrangian paths --- covariant quantum gravity --- emergent space-time --- Gaussian-like solutions --- entropy and time evolution --- resonances in quantum systems --- the Friedrichs model --- complex entropy. --- Bell’s theorem --- the causal arrow of time --- retrocausality --- superdeterminism --- toy-models --- quantum ontology --- sub-quantum dynamics --- micro-constituents --- emergent space-time --- emergent quantum gravity --- entropic gravity --- black hole thermodynamics --- Stern-Gerlach --- trajectories --- spin --- Bell theorem --- fractal geometry --- p-adic metric --- singular limit --- gravity --- conspiracy --- free will --- number theory --- quantum potential --- Feynman paths --- weak values --- Bohm theory --- no-hidden-variables theorems --- observables --- measurement problem --- Bohmian mechanics --- primitive ontology --- Retrocausation --- weak values --- Stochastic Electrodynamics --- quantum mechanics --- decoherence --- interpretations --- pilot-wave theory --- Bohmian mechanics --- Born rule statistics --- measurement problem --- quantum thermodynamics --- strong coupling --- operator thermodynamic functions --- quantum theory --- de Broglie–Bohm theory --- contextuality --- atom-surface scattering --- bohmian mechanics --- matter-wave optics --- diffraction --- vortical dynamics --- Schrödinger equation --- de Broglie–Bohm theory --- nonequilibrium thermodynamics --- zero-point field --- de Broglie–Bohm interpretation of quantum mechanics --- pilot wave --- interior-boundary condition --- ultraviolet divergence --- quantum field theory --- Aharonov–Bohm effect --- physical ontology --- nomology --- interpretation --- gauge freedom --- Canonical Presentation --- relational space --- relational interpretation of quantum mechanics --- measurement problem --- non-locality --- discrete calculus --- iterant --- commutator --- diffusion constant --- Levi-Civita connection --- curvature tensor --- constraints --- Kilmister equation --- Bianchi identity --- stochastic differential equations --- Monte Carlo simulations --- Burgers equation --- Langevin equation --- fractional velocity --- interpretations of quantum mechanics --- David Bohm --- mind–body problem --- quantum holism --- fundamental irreversibility --- space-time fluctuations --- spontaneous state reduction --- Poincaré recurrence --- symplectic camel --- quantum mechanics --- Hamiltonian --- molecule interference --- matter-waves --- metrology --- magnetic deflectometry --- photochemistry --- past of the photon --- Mach–Zehnder interferometer --- Dove prism --- photon trajectory --- weak measurement --- transition probability amplitude --- atomic metastable states --- Bell’s theorem --- Bohmian mechanics --- nonlocality --- many interacting worlds --- wavefunction nodes --- bouncing oil droplets --- stochastic quantum dynamics --- de Broglie–Bohm theory --- quantum non-equilibrium --- H-theorem --- ergodicity --- ontological quantum mechanics --- objective non-signaling constraint --- quantum inaccessibility --- epistemic agent --- emergent quantum state --- self-referential dynamics --- dynamical chaos --- computational irreducibility --- undecidable dynamics --- Turing incomputability --- quantum ontology --- nonlocality --- time-symmetry --- retrocausality --- quantum causality --- conscious agent --- emergent quantum mechanics --- Bohmian mechanics --- de Broglie-Bohm theory

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