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Mechanisms of antibiotic resistance

Authors: --- --- --- --- et al.
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195268 Year: Pages: 224 DOI: 10.3389/978-2-88919-526-8 Language: English
Publisher: Frontiers Media SA
Subject: Microbiology --- Science (General)
Added to DOAB on : 2015-12-10 11:59:06
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Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Flow and Transport Properties of Unconventional Reservoirs 2018

Authors: --- --- ---
ISBN: 9783039211166 / 9783039211173 Year: Pages: 364 DOI: 10.3390/books978-3-03921-117-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-08-28 11:21:27
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Unconventional reservoirs are usually complex and highly heterogeneous, such as shale, coal, and tight sandstone reservoirs. The strong physical and chemical interactions between fluids and pore surfaces lead to the inapplicability of conventional approaches for characterizing fluid flow in these low-porosity and ultralow-permeability reservoir systems. Therefore, new theories and techniques are urgently needed to characterize petrophysical properties, fluid transport, and their relationships at multiple scales for improving production efficiency from unconventional reservoirs. This book presents fundamental innovations gathered from 21 recent works on novel applications of new techniques and theories in unconventional reservoirs, covering the fields of petrophysical characterization, hydraulic fracturing, fluid transport physics, enhanced oil recovery, and geothermal energy. Clearly, the research covered in this book is helpful to understand and master the latest techniques and theories for unconventional reservoirs, which have important practical significance for the economic and effective development of unconventional oil and gas resources.

Keywords

fracturing fluid --- rheology --- chelating agent --- viscosity --- polymer --- fluid-solid interaction --- velocity profile --- the average flow velocity --- flow resistance --- pore network model --- shale gas --- volume fracturing --- finite volume method --- production simulation --- multi-scale flow --- multi-scale fracture --- shale gas reservoir --- fractured well transient productivity --- succession pseudo-steady state (SPSS) method --- complex fracture network --- multi-scale flow --- analysis of influencing factors --- tight sandstones --- spontaneous imbibition --- remaining oil distributions --- imbibition front --- imbibition recovery --- NMR --- slip length --- large density ratio --- contact angle --- pseudo-potential model --- lattice Boltzmann method --- micro-fracture --- dissolved gas --- experimental evaluation --- reservoir depletion --- recovery factor --- tight oil --- Lucaogou Formation --- tight oil --- pore structure --- prediction by NMR logs --- tight oil reservoir --- SRV-fractured horizontal well --- multiporosity and multiscale --- flow regimes --- productivity contribution degree of multimedium --- equilibrium permeability --- non-equilibrium permeability --- matrix–fracture interaction --- effective stress --- coal deformation --- porous media --- non-linear flow --- conformable derivative --- fractal --- hydraulic fracturing --- tight reservoirs --- fracture diversion --- extended finite element method --- fracture network --- gas adsorption capacity --- shale reservoirs --- influential factors --- integrated methods --- sulfonate gemini surfactant --- thickener --- temperature-resistance --- clean fracturing fluid --- low-salinity water flooding --- clay mineral composition --- enhanced oil recovery --- wetting angle --- pH of formation water --- fractional diffusion --- fractal geometry --- analytical model --- shale gas reservoir --- carbonate reservoir --- petrophysical characterization --- pore types --- pore structure --- permeability --- fractal dimension --- reservoir classifications --- deep circulation groundwater --- groundwater flow --- geothermal water --- faults --- isotopes --- shale permeability --- local effect --- global effect --- matrix-fracture interactions --- nanopore --- pore structure --- shale --- tight sandstone --- mudstone --- nitrogen adsorption --- fractal --- enhanced geothermal system --- well-placement optimization --- fracture continuum method --- 0-1 programming --- unconventional reservoirs --- petrophysical characterization --- fluid transport physics

Antimicrobial Resistance in Environmental Waters

Authors: ---
ISBN: 9783038976080 9783038976097 Year: Pages: 188 DOI: 10.3390/books978-3-03897-609-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Environmental Engineering
Added to DOAB on : 2019-05-09 17:16:14
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This Special Issue on Antimicrobial Resistance in Environmental Waters features 11 articles on the monitoring and surveillance of antimicrobial resistance (AMR) in natural aquatic systems (i.e., reservoirs, rivers), and effluent discharge from water treatment plants to assess the effectiveness of AMR removal and resulting loads in treated waters. Some of the key elements of AMR studies presented in this Special Issue highlight the underlying drivers of AMR contamination in the environment and the evaluation of the hazard imposed on aquatic organisms in receiving environments through ecological risk assessments. As described in this Issue, screening antimicrobial peptide (AMP) libraries for biofilm disruption and antimicrobial candidates are promising avenues for the development of new treatment options to eradicate resistance.

Emerging Advances in Petrophysics. Porous Media Characterization and Modeling of Multiphase Flow

Authors: --- --- ---
ISBN: 9783038977940 9783038977957 Year: Pages: 258 DOI: 10.3390/books978-3-03897-795-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Physics (General) --- Geophysics and Geomagnetism
Added to DOAB on : 2019-04-25 16:37:17
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Due to the influence of pore-throat size distribution, pore connectivity, and microscale fractures, the transport, distribution, and residual saturation of fluids in porous media are difficult to characterize. Petrophysical methods in natural porous media have attracted great attention in a variety of fields, especially in the oil and gas industry. A wide range of research studies have been conducted on the characterization of porous media covers and multiphase flow therein. Reliable approaches for characterizing microstructure and multiphase flow in porous media are crucial in many fields, including the characterization of residual water or oil in hydrocarbon reservoirs and the long-term storage of supercritical CO2 in geological formations. This book gathers together 15 recent works to emphasize fundamental innovations in the field and novel applications of petrophysics in unconventional reservoirs, including experimental studies, numerical modeling (fractal approach), and multiphase flow modeling/simulations. The relevant stakeholders of this book are authorities and service companies working in the petroleum, subsurface water resources, air and water pollution, environmental, and biomaterial sectors.

Keywords

Wilkins equation --- non-laminar flow --- turbulence modelling --- porous media --- oil tanker --- temperature drop --- oscillating motion --- numerical simulation --- soil-water characteristic curve --- initial void ratio --- air-entry value --- fractal dimension --- fractal model --- oil properties --- diffusion coefficient --- supercritical CO2 --- Peng-Robinson equation of state (PR EOS) --- CT --- digital rock --- microfractures --- Lattice Boltzmann method --- pore-scale simulations --- tight sandstone --- pore structure --- multifractal --- classification --- Ordos Basin --- loose media --- coal --- porosity --- true density --- bulk density --- overburden pressure --- particle size --- tight conglomerate --- fracture characterization and prediction --- fractal method --- salt rock --- creep --- damage --- fractional derivative --- acoustic emission --- marine gas hydrate --- submarine landslide --- greenhouse gas emission --- lifecycle management --- hazard prevention --- multilayer reservoir --- interlayer interference --- producing degree --- seepage resistance --- wellbore multiphase flow --- inclined angle --- liquid rate --- gas rate --- pressure drawdown model with new coefficients --- base-level cycle --- pore structure --- mouth bar sand body --- Huanghua Depression --- isotopic composition --- methane --- gas hydrate --- South China Sea --- Bakken Formation --- pore structure --- controlling factors --- low-temperature nitrogen adsorption --- petrophysics --- fractal porous media --- unconventional reservoirs --- multiphase flow

Adaptive Catchment Management and Reservoir Operation

Authors: --- ---
ISBN: 9783038977384 / 9783038977391 Year: Pages: 498 DOI: 10.3390/books978-3-03897-739-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-08-28 11:21:27
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River catchments and reservoirs play a central role in water security, food supply, flood risk management, hydropower generation, and ecosystem services; however, they are now under increasing pressure from population growth, economic activities, and changing climate means and extremes in many parts of the world. Adaptive management of river catchments and reservoirs requires an in-depth understanding of the impacts of future uncertainties and thus the development of robust, sustainable solutions to meet the needs of various stakeholders and the environment. To tackle the huge challenges in moving towards adaptive catchment management, this book presents the latest developments in cutting-edge knowledge, novel methodologies, innovative management strategies, and case studies, focusing on the following themes: reservoir dynamics and impact analysis of dam construction, optimal reservoir operation, climate change impacts on hydrological processes and water management, and integrated catchment management.

Keywords

Siemianówka --- hydrology --- Narew River --- dam --- reservoir --- discharge --- flow regime --- reservoir flushing --- numerical simulation --- flushing efficiency --- Kurobe River --- two-dimensional bed evolution model --- sediment flushing of empty storage --- shaft spillway pipe --- sediment flushing efficiency --- sediment regime --- suspended sediment concentration --- vertical profiles of concentration --- Jingjiang River Reach --- Yangtze River --- CO2 --- reservoirs --- general regression neural network --- back propagation neural network --- climate change --- CMIP3 --- CMIP5 --- downscaling --- runoff response --- SWAT model --- stochastic linear programming --- Markov chain --- reliability --- vulnerability --- reservoir operation --- stochastic dynamic programming --- protection zone --- nutrient uptake --- NPP --- South-to-North Water Transfer Project --- Miyun Reservoir --- reservoir operation --- optimization --- SWAT --- HEC-ResPRM --- climate change --- CORDEX-Africa --- Tekeze basin --- long distance water diversion --- inverted siphon --- sensitivity analysis --- integrated supply system modeling --- sediment regime --- suspended sediment concentration --- vertical profiles of concentration --- the Jingjiang River Reach --- the Yangtze River --- reservoir operation --- multi-stage stochastic optimization --- TB-MPC --- flood control --- real-time control --- energy --- hydropower stations --- differential evolution algorithm --- optimal scheduling --- ?-constrained method --- drinking water resources --- water environmental capacity (WEC) --- Environmental Fluid Dynamics Code (EFDC) model --- the Huangshi Reservoir --- seasonal rainfall --- upper Chao Phraya River Basin --- El Niño/Southern Oscillation --- Indian Monsoon --- sea surface temperatures --- reverse regulation --- coupling model --- aftereffect --- accompanying progressive optimality algorithm --- Dokan Dam --- runoff --- sediment load --- SWAT --- natural flow regime --- multi-objective model --- uncertainty --- genetic algorithm --- land and water resources --- system dynamics --- modeling --- scenario analysis --- Heilongjiang --- tropical reservoir --- heating impact --- Langcang-Mekong River --- Kappa distribution --- parameter relation --- partial gauged basin --- power function --- ratio curve --- ungauged basin --- reservoir operation --- integrated surface water-groundwater model --- Heihe River Basin --- environmental flow --- irrigation --- design and operation of the multipurpose reservoir --- water deficit --- reservoir simulation model --- climate change --- multi-objective optimization NSGA II --- resilience and robustness --- costs and benefits --- water energy --- multi-agent of river basin --- game theory --- water resources allocation --- optimal flood control operation --- cascade reservoirs --- dynamic programming with progressive optimality algorithm (DP-POA) --- the upper Yangtze River Basin --- parameterization --- simulation --- optimization --- direct policy search --- hedging policy --- shortage ratio: Vulnerability --- NSGA-II --- lentic habitats --- bitterling --- mussel --- floodplain vertical shape index --- sediment management --- adaptive management --- catchment modelling --- integrated management --- reservoir operation

Application of the China Meteorological Assimilation Driving Datasets for the SWAT Model (CMADS) in East Asia

Authors: ---
ISBN: 9783039212354 / 9783039212361 Year: Pages: 384 DOI: 10.3390/books978-3-03921-236-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Geography
Added to DOAB on : 2019-08-28 11:21:27
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To promote scientific understanding of surface processes in East Asia, we have published details of the CMADS dataset in the journal, Water, and expect that users around the world will learn about CMADS datasets while promoting the development of hydrometeorological disciplines in East Asia. We hope and firmly believe that scientific development in East Asia and our understanding of this typical region will be further advanced.

Keywords

East Asia --- CMADS --- meteorological input uncertainty --- hydrological modelling --- SWAT --- non-point source pollution models --- CMADS --- Qinghai-Tibet Plateau (TP) --- SWAT --- CFSR --- TRMM --- PERSIANN --- PERSIANN-CDR --- CMADS --- satellite-derived rainfall --- streamflow simulation --- SWAT --- Han River --- GLUE --- hydrological model --- ParaSol --- SUFI2 --- uncertainty analysis --- SWAT model --- CMADS --- Lijiang River --- runoff --- uncertainty analysis --- hydrological elements --- statistical analysis --- SWAT --- CMADS --- climate variability --- land use change --- streamflow --- potential evapotranspiration --- Penman-Monteith --- CMADS --- China --- CMADS dataset --- parameter sensitivity --- SUFI-2 --- Yellow River --- reanalysis products --- satellite-based products --- hydrological model --- bayesian model averaging --- Xiang River basin --- total nitrogen --- accumulation --- SWAT model --- CMADS --- Biliuhe reservoir --- CMADS --- SWAT --- East Asia --- meteorological --- hydrological --- precipitation --- TMPA-3B42V7 --- CMADS --- hydrologic model --- uncertainty --- reservoirs --- operation rule --- Noah LSM-HMS --- capacity distribution --- aggregated reservoir --- CMADS --- CMADS --- IMERG --- statistical analysis --- SWAT hydrological simulation --- Jinsha River Basin --- blue and green water flows --- climate variability --- sensitivity analysis --- Erhai Lake Basin --- CMADS --- SWAT --- JBR --- soil moisture --- hydrological processes --- spatio-temporal --- sloping black soil farmland --- soil moisture content --- freeze–thaw period --- soil temperature --- CMADS-ST --- reservoir parameters --- runoff --- CMADS --- SWAT --- Yalong River --- CMADS --- impact --- hydrological modeling --- SWAT --- runoff --- sediment yield --- land-use change --- SWAT --- CMADS

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