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Natural Compounds as New Cancer Treatments

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ISBN: 9783039213658 9783039213665 Year: Pages: 128 DOI: 10.3390/books978-3-03921-366-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2019-12-09 11:49:15
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Cancer remains one of the main causes of morbidity and mortality worldwide. Although many pharmacological and clinical advances have been made, there is a constant need for new molecules to improve the overall options for treatment. Natural compounds from animal, microbial, vegetal, or fungal origin represent countless sources of new compounds that can be used as anticancer drugs, provided their activity, bioavailability, and toxicity are adequate. This book aims to compile both original articles and reviews that cover the most recent advances in the use of natural compounds for cancer treatment, and provide new objectives and advice for future research in the field of biological activity of natural compounds.

Nanoporous Materials and Their Applications

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ISBN: 9783038979685 9783038979692 Year: Pages: 168 DOI: 10.3390/books978-3-03897-969-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Physics (General)
Added to DOAB on : 2019-06-26 08:44:06
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This book is a special collection of articles dedicated to the preparation and characterization of nanoporous materials, such as zeolitic-type materials, mesoporous silica (SBA-15, MCM-41, and KIT-6), mesoporous metallic oxides, metal–organic framework structures (MOFs), and pillared clays, and their applications in adsorption, catalysis, and separation processes. This book presents a global vision of researchers from international universities, research centers, and industries working with nanoporous materials and shares the latest results on the synthesis and characterization of such materials, which have given rise to the special interest in their applications in basic and industrial processes.

Seedling Production and Field Performance of Seedlings

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ISBN: 9783039212552 9783039212569 Year: Pages: 192 DOI: 10.3390/books978-3-03921-256-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General)
Added to DOAB on : 2019-12-09 11:49:15
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Rapid establishment of seedlings in forest regeneration or afforestation sites after planting is a prerequisite for a successful reforestation. Seedling survival after outplanting can be improved by using high-quality seedling material. Seedling quality consists of several features, such as genetic source, morphological properties, nutritional status, stress resistance, and vitality of the seedlings. Field performance of the seedlings is a complex process which can be affected by many nursery and silvicultural practices. Nursery cultural practices strongly affect seedling quality, which is generally at its highest level during the growth period at the nursery. Afterwards, when the seedlings are transported from the nursery to the planting site (including seedling storage, handling, shipping, and planting practices), the quality of seedlings can only remain the same or decline. To ensure successful regeneration, it is important to produce seedlings that retain their high quality until planting, and to establish them quickly in the forest regeneration site.

Advances in Near Infrared Spectroscopy and Related Computational Methods

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ISBN: 9783039280520 9783039280537 Year: Pages: 496 DOI: 10.3390/books978-3-03928-053-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General) --- Analytical Chemistry
Added to DOAB on : 2020-01-30 16:39:46
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In the last few decades, near-infrared (NIR) spectroscopy has distinguished itself as one of the most rapidly advancing spectroscopic techniques. Mainly known as an analytical tool useful for sample characterization and content quantification, NIR spectroscopy is essential in various other fields, e.g. NIR imaging techniques in biophotonics, medical applications or used for characterization of food products. Its contribution in basic science and physical chemistry should be noted as well, e.g. in exploration of the nature of molecular vibrations or intermolecular interactions. One of the current development trends involves the miniaturization and simplification of instrumentation, creating prospects for the spread of NIR spectrometers at a consumer level in the form of smartphone attachments—a breakthrough not yet accomplished by any other analytical technique. A growing diversity in the related methods and applications has led to a dispersion of these contributions among disparate scientific communities. The aim of this Special Issue was to bring together the communities that may perceive NIR spectroscopy from different perspectives. It resulted in 30 contributions presenting the latest advances in the methodologies essential in near-infrared spectroscopy in a variety of applications.

Keywords

hyperspectral imaging --- variety discrimination --- Chrysanthemum --- deep convolutional neural network --- DNA --- FTIR spectroscopy --- rapid identification --- PLS-DA --- animal origin --- near-infrared hyperspectral imaging --- raisins --- support vector machine --- pixel-wise --- object-wise --- maize kernel --- hyperspectral imaging technology --- accelerated aging --- principal component analysis --- support vector machine model --- standard germination tests --- blackberries --- Rubus fructicosus --- phenolics --- carotenoids --- bioanalytical applications --- near infrared --- chemometrics --- VIS/NIR hyperspectral imaging --- corn seed --- classification --- freeze-damaged --- image processing --- imaging visualization --- wavelength selection --- NIR spectroscopy --- binary dragonfly algorithm --- ensemble learning --- quantitative analysis modeling --- NIR --- SCiO --- pocket-sized spectrometer --- cheese --- fat --- moisture --- multivariate data analysis --- Fourier-transform near-infrared spectroscopy --- glucose --- fructose --- dry matter --- partial least square regression --- Ewing sarcoma --- Fourier transform infrared spectroscopy --- FTIR --- chemotherapy --- bone cancer --- calibration transfer --- NIR spectroscopy --- PLS --- quantitative analysis model --- melamine --- FT-IR --- NIR spectroscopy --- quantum chemical calculation --- anharmonic calculation --- overtones --- combination bands --- near infrared spectroscopy --- Trichosanthis Fructus --- geographical origin --- chemometric techniques --- crude drugs --- prepared slices --- support vector machine-discriminant analysis --- near-infrared fluorescence --- fluorescent probes --- Zn(II) --- di-(2-picolyl)amine --- living cells --- cellular imaging --- near-infrared (NIR) spectroscopy --- calibration transfer --- affine invariance --- multivariate calibration --- partial least squares (PLS) --- NIR --- direct model transferability --- MicroNIR™ --- SVM --- hier-SVM --- SIMCA --- PLS-DA --- TreeBagger --- PLS --- calibration transfer --- agriculture --- photonics --- imaging --- spectral imaging --- spectroscopy --- handheld near-infrared spectroscopy --- pasta/sauce blends --- partial least squares calibration --- nutritional parameters --- bootstrapping soft shrinkage --- partial least squares --- extra virgin olive oil --- adulteration --- FT-NIR spectroscopy --- near-infrared spectroscopy --- ethanol --- anharmonic quantum mechanical calculations --- isotopic substitution --- overtones --- combinations bands --- seeds vitality --- rice seeds --- near-infrared spectroscopy --- hyperspectral image --- discriminant analysis --- near-infrared spectroscopy --- counter propagation artificial neural network --- detection --- auxiliary diagnosis --- BRAF V600E mutation --- colorectal cancer --- tissue --- paraffin-embedded --- deparaffinized --- stained --- ultra-high performance liquid chromatography --- Folin–Ciocalteu --- total hydroxycinnamic derivatives --- phytoextraction --- near-infrared spectroscopy --- origin traceability --- data fusion --- Paris polyphylla var. yunnanensis --- Fourier transform mid-infrared spectroscopy --- near-infrared spectroscopy --- aquaphotomics --- water --- light --- near infrared spectroscopy --- water-mirror approach --- perturbation --- biomeasurements --- biodiagnosis --- biomonitoring --- Vitis vinifera L. --- proximal sensing --- precision viticulture --- near infrared --- chemometrics --- non-destructive sensor --- NIRS --- osteopathy --- late preterm --- brain --- splanchnic --- Raman spectroscopy --- hyperspectral imaging --- analytical spectroscopy --- counterfeit and substandard pharmaceuticals --- DFT calculations --- chemometrics --- PLSR --- API --- lumefantrine --- artemether --- antimalarial tablets --- FT-NIR spectroscopy --- PLS-R --- water --- glucose --- test set validation --- RMSEP --- hyperspectral image processing --- perfusion measurements --- clinical classifications --- n/a

Plant Proteomic Research 2.0

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ISBN: 9783039210626 9783039210633 Year: Pages: 594 DOI: 10.3390/books978-3-03921-063-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Plant Sciences
Added to DOAB on : 2019-06-26 08:44:07
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Abstract

Advancements in high-throughput “Omics” techniques have revolutionized plant molecular biology research. Proteomics offers one of the best options for the functional analysis of translated regions of the genome, generating a wealth of detailed information regarding the intrinsic mechanisms of plant stress responses. Various proteomic approaches are being exploited extensively for elucidating master regulator proteins which play key roles in stress perception and signaling, and these approaches largely involve gel-based and gel-free techniques, including both label-based and label-free protein quantification. Furthermore, post-translational modifications, subcellular localization, and protein–protein interactions provide deeper insight into protein molecular function. Their diverse applications contribute to the revelation of new insights into plant molecular responses to various biotic and abiotic stressors.

Keywords

Phalaenopsis --- petal --- pollination --- senescence --- 2-DE --- ROS --- Medicago sativa --- leaf cell wall proteome --- cadmium --- quantitative proteomics --- 2D DIGE --- chloroplast --- elevated CO2 --- heat stress --- nucleotide pyrophosphatase/phosphodiesterase --- (phospho)-proteomics --- photosynthesis --- protein phosphorylation --- 14-3-3 proteins --- Oryza sativa L. --- starch --- sucrose --- N utilization efficiency --- proteomics --- 2D --- protein phosphatase --- rice isogenic line --- SnRK1 --- 14-3-3 --- lettuce --- bolting --- proteome --- high temperature --- iTRAQ --- proteome profiling --- iTRAQ --- differentially abundant proteins (DAPs) --- drought stress --- physiological responses --- Zea mays L. --- GS3 --- ? subunit --- heterotrimeric G protein --- mass spectrometric analysis --- RGG3 --- rice --- western blotting --- Dn1-1 --- ?-subunit --- heterotrimeric G protein --- mass spectrometry analysis --- RGG4 --- rice --- western blotting --- Clematis terniflora DC. --- polyphenol oxidase --- virus induced gene silencing --- photosynthesis --- glycolysis --- Camellia sinensis --- chlorotic mutation --- chlorophyll deficiency --- weakening of carbon metabolism --- iTRAQ --- proteomics --- degradome --- wheat --- cultivar --- protease --- papain-like cysteine protease (PLCP) --- subtilase --- metacaspase --- caspase-like --- wheat leaf rust --- Puccinia recondita --- Stagonospora nodorum --- iTRAQ --- proteomics --- somatic embryogenesis --- pyruvate biosynthesis --- Zea mays --- chlorophylls --- LC-MS-based proteomics --- pea (Pisum sativum L.) --- proteome functional annotation --- proteome map --- seeds --- seed proteomics --- late blight disease --- potato proteomics --- Phytophthora infestans --- Sarpo Mira --- early and late disease stages --- Simmondsia chinensis --- cold stress --- proteomics --- leaf --- iTRAQ --- Ricinus communis L. --- cold stress --- seed imbibition --- iTRAQ --- proteomics --- Morus --- organ --- gel-free/label-free proteomics --- flavonoid --- antioxidant activity --- phosphoproteome --- barley --- seed dormancy --- germination --- imbibition --- after-ripening --- sugarcane --- Sporisorium scitamineum --- smut --- proteomics --- RT-qPCR --- ISR --- holm oak --- Quercus ilex --- 2-DE proteomics --- shotgun proteomics --- non-orthodox seed --- population variability --- stresses responses --- ammonium --- Arabidopsis thaliana --- carbon metabolism --- nitrogen metabolism --- nitrate --- proteomics --- root --- secondary metabolism --- proteomics --- wheat --- silver nanoparticles --- plant pathogenesis responses --- data-independent acquisition --- quantitative proteomics --- Pseudomonas syringae --- sweet potato plants infected by SPFMV --- SPV2 and SPVG --- sweet potato plants non-infected by SPFMV --- SPV2 and SPVG --- co-infection --- transcriptome profiling --- gene ontology --- pathway analysis --- lesion mimic mutant --- leaf spot --- phenylpropanoid biosynthesis --- proteomics --- isobaric tags for relative and absolute quantitation (iTRAQ) --- rice --- affinity chromatography --- ergosterol --- fungal perception --- innate immunity --- pattern recognition receptors --- plasma membrane --- proteomics --- proteomics --- maize --- plant-derived smoke --- shoot --- Solanum tuberosum --- patatin --- seed storage proteins --- vegetative storage proteins --- tuber phosphoproteome --- targeted two-dimensional electrophoresis --- B. acuminata petals --- MALDI-TOF/TOF --- GC-TOF-MS --- qRT-PCR --- differential proteins --- n/a

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