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Evolution von Relationen in temporalen partiten Themen-Graphen

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ISBN: 9783731503408 Year: Pages: II, 136 p. DOI: 10.5445/KSP/1000045521 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Business and Management
Added to DOAB on : 2019-07-30 20:02:00
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In this work a model is engineered to depict topic relationships as graphs between detected topics of different time windows. By varying and shifting the time span of consideration the relationships between topics can be mapped with a variable complexity including the topic frequencies. Topic life cycles as well as changes in thematic relationships and their evolution become perceptible. Topics found can be matched in structure as well as their temporal progression to existing events.

Neuroanatomy for the XXIst Century

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199167 Year: Pages: 199 DOI: 10.3389/978-2-88919-916-7 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2016-01-19 14:05:46
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An explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolution experimental approaches. A major goal of this e-Book is thus to highlight in one place the impressive range of available techniques, even as these are fast becoming routine. This is not meant as a technical review, however, but rather will project the technical explosion as indicative of a field now in a vibrant state of renewal. Thus, contributions will be mainly research articles using the newer techniques. A second goal is to showcase what has become the conspicuous interdisciplinary reach of the field: neuroanatomical standards and the close association of structure-function and underlying circuitry mechanisms are increasingly relevant to investigations in development, physiology, and disease. Another feature of this Research Topic is that it includes a breadth of cross-species contributions from investigators working with rodent, nonhuman primate, and human brains. This is important since most of our current knowledge of brain structure has been obtained from experimental animals. However, recent technical advances, coupled with researcher willingness to use the human tissue available, will undoubtedly lead to major advances in the near future regarding human brain mapping and connectomes. Thus, of particular interest will be the methods that can help to define general wiring principles in the brain, both structural and functional. Overall, the state of the field is: exciting.

Clinical Text Mining: Secondary Use of Electronic Patient Records

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ISBN: 9783319785028 9783319785035 Year: Pages: 181 DOI: https://doi.org/10.1007/978-3-319-78503-5 Language: English
Publisher: Springer Grant: Riksbankens Jubileumsfond; Stockholm University
Subject: Medicine (General)
Added to DOAB on : 2018-06-22 15:52:54
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This open access book describes the results of natural language processing and machine learning methods applied to clinical text from electronic patient records.It is divided into twelve chapters. Chapters 1-4 discuss the history and background of the original paper-based patient records, their purpose, and how they are written and structured. These initial chapters do not require any technical or medical background knowledge. The remaining eight chapters are more technical in nature and describe various medical classifications and terminologies such as ICD diagnosis codes, SNOMED CT, MeSH, UMLS, and ATC. Chapters 5-10 cover basic tools for natural language processing and information retrieval, and how to apply them to clinical text. The difference between rule-based and machine learning-based methods, as well as between supervised and unsupervised machine learning methods, are also explained. Next, ethical concerns regarding the use of sensitive patient records for research purposes are discussed, including methods for de-identifying electronic patient records and safely storing patient records. The book’s closing chapters present a number of applications in clinical text mining and summarise the lessons learned from the previous chapters.The book provides a comprehensive overview of technical issues arising in clinical text mining, and offers a valuable guide for advanced students in health informatics, computational linguistics, and information retrieval, and for researchers entering these fields.

Computational Systems Biology of Pathogen-Host Interactions

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198214 Year: Pages: 198 DOI: 10.3389/978-2-88919-821-4 Language: English
Publisher: Frontiers Media SA
Subject: Microbiology --- Science (General)
Added to DOAB on : 2016-01-19 14:05:46
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A thorough understanding of pathogenic microorganisms and their interactions with host organisms is crucial to prevent infectious threats due to the fact that Pathogen-Host Interactions (PHIs) have critical roles in initiating and sustaining infections. Therefore, the analysis of infection mechanisms through PHIs is indispensable to identify diagnostic biomarkers and next-generation drug targets and then to develop strategic novel solutions against drug-resistance and for personalized therapy. Traditional approaches are limited in capturing mechanisms of infection since they investigate hosts or pathogens individually. On the other hand, the systems biology approach focuses on the whole PHI system, and is more promising in capturing infection mechanisms. Here, we bring together studies on the below listed sections to present the current picture of the research on Computational Systems Biology of Pathogen-Host Interactions:- Computational Inference of PHI Networks using Omics Data- Computational Prediction of PHIs- Text Mining of PHI Data from the Literature- Mathematical Modeling and Bioinformatic Analysis of PHIs Computational Inference of PHI Networks using Omics Data Gene regulatory, metabolic and protein-protein networks of PHI systems are crucial for a thorough understanding of infection mechanisms. Great advances in molecular biology and biotechnology have allowed the production of related omics data experimentally. Many computational methods are emerging to infer molecular interaction networks of PHI systems from the corresponding omics data. Computational Prediction of PHIs Due to the lack of experimentally-found PHI data, many computational methods have been developed for the prediction of pathogen-host protein-protein interactions. Despite being emerging, currently available experimental PHI data are far from complete for a systems view of infection mechanisms through PHIs. Therefore, computational methods are the main tools to predict new PHIs. To this end, the development of new computational methods is of great interest. Text Mining of PHI Data from Literature Despite the recent development of many PHI-specific databases, most data relevant to PHIs are still buried in the biomedical literature, which demands for the use of text mining techniques to unravel PHIs hidden in the literature. Only some rare efforts have been performed to achieve this aim. Therefore, the development of novel text mining methods specific for PHI data retrieval is of key importance for efficient use of the available literature. Mathematical Modeling and Bioinformatic Analysis of PHIs After the reconstruction of PHI networks experimentally and/or computationally, their mathematical modeling and detailed computational analysis is required using bioinformatics tools to get insights on infection mechanisms. Bioinformatics methods are increasingly applied to analyze the increasing amount of experimentally-found and computationally-predicted PHI data. Acknowledgements: We, editors of this e-book, acknowledge Emrah Nikerel (Yeditepe University, Turkey) and Arzucan Özgür (Bogaaziçi University, Turkey) for their contributions during the initiation of the Research Topic.

Human and Animal Sensitivity: How Stock-People and Consumer Perception Can Affect Animal Welfare

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ISBN: 9783039212613 / 9783039212620 Year: Pages: 234 DOI: 10.3390/books978-3-03921-262-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Animal Sciences
Added to DOAB on : 2019-12-09 11:49:15
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This book presents cross-discipline studies covering aspects ranging from animal science to social/consumer sciences and psychology, with the aim to collect and disseminate information promoting the continuous enhancement of animal welfare by improving stakeholders’ perception of animal welfare. Although animal welfare is about how the animals perceive the surrounding environment, the actual welfare of the animals is dependent on how the stakeholders perceive and weigh animal welfare. The stakeholders can, either directly (i.e., through stock-people interaction with the animals) or indirectly (e.g., when retailers and consumers are willing to pay more for high welfare animal-based products), affect the way animals are kept and handled.

Keywords

veterinary student --- animal ethics --- pain perception --- animal --- animal welfare --- Animal welfare --- husbandry practices --- lambs --- pain --- sheep farmers --- perception --- agreement --- aggression --- animal welfare --- desensitization --- perception --- pigs --- animal welfare --- young adult --- animal attitudes --- children --- farm animals --- animal welfare --- education --- technology --- animal welfare --- Asia --- knowledge --- slaughter --- transport --- training --- animal welfare --- benefit --- profit --- human health --- Asia --- livestock --- farmer perception --- citizen perception --- qualitative research --- free elicitation narrative interviews --- animal welfare --- consumer --- willingness to pay --- pig --- castration --- immunocastration --- information --- survey --- human-animal relationship --- fear --- laying hen --- stockpeople attitudes --- stockperson behaviour --- egg farm --- albumen corticosterone --- welfare --- animal welfare --- stakeholder perception --- text mining --- horse --- donkey --- goat --- sheep --- turkey --- farm animal welfare (FAW) --- willingness to pay --- food safety concerns --- ethical concerns --- perceived consumer effectiveness --- broiler --- dairy buffalo --- human-animal relationship --- animal behavior --- test-retest reliability --- avoidance distance --- milk production --- animal welfare --- animal welfare --- stunning --- religious slaughter --- veterinary students --- Halal meat --- racehorse welfare --- staff shortages --- horse–human relationship --- standards of care --- employee relations --- consumer demand --- economics --- farm animal welfare --- producer perspective

Empirical Finance

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ISBN: 9783038977063 Year: Pages: 276 DOI: 10.3390/books978-3-03897-707-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Economics
Added to DOAB on : 2019-04-05 10:34:31
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There is no denying the role of empirical research in finance and the remarkable progress of empirical techniques in this research field. This Special Issue focuses on the broad topic of “Empirical Finance” and includes novel empirical research associated with financial data. One example includes the application of novel empirical techniques, such as machine learning, data mining, wavelet transform, copula analysis, and TV-VAR, to financial data. The Special Issue includes contributions on empirical finance, such as algorithmic trading, market efficiency, market microstructure, portfolio theory and asset allocation, asset pricing models, liquidity risk premium, currency crisis, return predictability, and volatility modeling.

Keywords

text similarity --- text mining --- machine learning --- SVM --- neural network --- LSTM --- credit risk --- ensemble learning --- deep learning --- bagging --- random forest --- boosting --- deep neural network --- causality-in-variance --- cross-correlation function --- housing and stock markets --- algorithmic trading --- take profit --- stop loss --- MACD --- ATR --- city banks --- dependence structure --- copula --- n/a --- market microstructure --- price discovery --- latency --- currency crisis --- random forests --- wavelet transform --- predictive accuracy --- housing price --- bank credit --- housing loans --- real estate development loans --- TVP-VAR model --- exchange rate --- volatility --- exports --- ARDL --- Vietnam --- crude oil futures prices forecasting --- convolutional neural networks --- short-term forecasting --- utility of international currency --- inertia --- liquidity risk premium --- US dollar --- Japanese yen --- cointegration --- statistical arbitrage --- natural gas --- wholesale electricity --- futures market --- spark spread --- earnings management --- earnings manipulation --- earnings quality --- initial public offering --- IPO --- asset pricing model --- data mining --- bankruptcy prediction --- financial and non-financial variables --- institutional investors’ shareholdings --- panel data model --- piecewise regression model --- global financial crisis --- gold return --- asymmetric dependence --- financial market stress --- robust regression --- quantile regression --- structural break --- flight to quality

Molecular Computing and Bioinformatics

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ISBN: 9783039211951 / 9783039211968 Year: Pages: 390 DOI: 10.3390/books978-3-03921-196-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Biotechnology
Added to DOAB on : 2019-08-28 11:21:27
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This text will provide the most recent knowledge and advances in the area of molecular computing and bioinformatics. Molecular computing and bioinformatics have a close relationship, paying attention to the same object but working towards different orientations. The articles will range from topics such as DNA computing and membrane computing to specific biomedical applications, including drug R&D and disease analysis.

Keywords

prostate cancer --- Mycoplasma hominis --- endoplasmic reticulum --- systems biology --- protein targeting --- biomedical text mining --- big data --- Tianhe-2 --- parallel computing --- load balancing --- bacterial computing --- bacteria and plasmid system --- Turing universality --- recursively enumerable function --- miRNA biogenesis --- structural patterns --- DCL1 --- protein–protein interaction (PPI) --- clustering --- protein complex --- penalized matrix decomposition --- avian influenza virus --- interspecies transmission --- amino acid mutation --- machine learning --- Bayesian causal model --- causal direction learning --- K2 --- brain storm optimization --- line graph --- Cartesian product graph --- join graph --- atom-bond connectivity index --- geometric arithmetic index --- P-glycoprotein --- efflux ratio --- in silico --- machine learning --- hierarchical support vector regression --- absorption --- distribution --- metabolism --- excretion --- toxicity --- image encryption --- chaotic map --- DNA coding --- Hamming distance --- Stenotrophomonas maltophilia --- iron acquisition systems --- iron-depleted --- RAST server --- NanoString Technologies --- siderophores --- gene fusion data --- gene susceptibility prioritization --- evaluating driver partner --- gene networks --- drug-target interaction prediction --- machine learning --- drug discovery --- microRNA --- environmental factor --- structure information --- similarity network --- bioinformatics --- identification of Chinese herbal medicines --- biochip technology --- DNA barcoding technology --- DNA strand displacement --- cascade --- 8-bit adder/subtractor --- domain label --- Alzheimer’s disease --- gene coding protein --- sequence information --- support vector machine --- classification --- adverse drug reaction prediction --- heterogeneous information network embedding --- stacking denoising auto-encoder --- meta-path-based proximity --- Panax ginseng --- oligopeptide transporter --- flowering plant --- phylogeny --- transcription factor --- multiple interaction networks --- function prediction --- multinetwork integration --- low-dimensional representation --- dihydrouridine --- nucleotide physicochemical property --- pseudo dinucleotide composition --- RNA secondary structure --- ensemble classifier --- diabetes mellitus --- hypoxia-inducible factor-1? --- angiogenesis --- bone formation --- osteogenesis --- protein transduction domain --- membrane computing --- edge detection --- enzymatic numerical P system --- resolution free --- molecular computing --- molecular learning --- DNA computing --- self-organizing systems --- pattern classification --- machine learning --- laccase --- Brassica napus --- lignification --- stress --- molecular computing --- bioinformatics --- machine learning --- protein --- DNA --- RNA --- drug --- bio-inspired

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