Search results: Found 5

Listing 1 - 5 of 5
Sort by
On the structure-property correlation and the evolution of Nanofeatures in 12-13.5% Cr oxide dispersion strengthened ferritic steels

Author:
Book Series: Schriftenreihe des Instituts für Angewandte Materialien, Karlsruher Institut für Technologie ISSN: 21929963 ISBN: 9783731501411 Year: Volume: 31 Pages: XX, 199 p. DOI: 10.5445/KSP/1000037337 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:57
License:

Loading...
Export citation

Choose an application

Abstract

Main objective of this work is to develop, by systematic variation of the chemical composition, and TMP, 14% Cr nano-structured ferritic alloys with significantly improved high-temperature properties compared to currently available ODS alloys. Application of state-of-the-art characterization tools shall lead to an integrated understanding of structure-property correlation and the formation mechanism of nanoparticles.

Small Scale Deformation using Advanced Nanoindentation Techniques

Authors: ---
ISBN: 9783038979661 / 9783038979678 Year: Pages: 168 DOI: 10.3390/books978-3-03897-967-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General)
Added to DOAB on : 2019-06-26 08:44:06
License:

Loading...
Export citation

Choose an application

Abstract

Small scale mechanical deformations have gained a significant interest over the past few decades, driven by the advances in integrated circuits and microelectromechanical systems. One of the most powerful and versatile characterization methods is the nanoindentation technique. The capabilities of these depth-sensing instruments have been improved considerably. They can perform experiments in vacuum and at high temperatures, such as in-situ SEM and TEM nanoindenters. This allows researchers to visualize mechanical deformations and dislocations motion in real time. Time-dependent behavior of soft materials has also been studied in recent research works. This Special Issue on ""Small Scale Deformation using Advanced Nanoindentation Techniques""; will provide a forum for researchers from the academic and industrial communities to present advances in the field of small scale contact mechanics. Materials of interest include metals, glass, and ceramics. Manuscripts related to deformations of biomaterials and biological related specimens are also welcome. Topics of interest include, but are not limited to:

Crystal Chemistry of Zinc, Cadmium and Mercury

Author:
ISBN: 9783038976523 Year: Pages: 156 DOI: 10.3390/books978-3-03897-653-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Organic Chemistry --- Chemistry (General) --- Science (General)
Added to DOAB on : 2019-04-05 10:34:31
License:

Loading...
Export citation

Choose an application

Abstract

This book is a printed edition of the Special Issue Crystal Chemistry of Zinc, Cadmium and Mercury that was published in Crystals

Curcumin in Health and Disease

Author:
ISBN: 9783039214495 / 9783039214501 Year: Pages: 274 DOI: 10.3390/books978-3-03921-450-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:15
License:

Loading...
Export citation

Choose an application

Abstract

The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

Keywords

brain ischemia --- curcumin --- Alzheimer’s disease --- neurodegeneration --- amyloid --- tau protein --- autophagy --- mitophagy --- apoptosis --- genes --- glioblastoma multiforme --- autophagy --- mitophagy --- curcumin --- chaperone-mediated autophagy --- Akt/mTOR signaling --- transmission electron microscopy --- Curcuma longa --- turmeric tuber --- Zingiberaceae --- TLC bioautography --- antimicrobial agents --- ImageJ --- TLC-MS --- hydrostatic counter-current chromatography --- centrifugal partition chromatography --- curcumin --- death receptor --- apoptosis --- curcumin --- anticancer --- structure activity relationship --- cellular pathway --- mechanism of action --- delivery system --- wound --- wound healing --- diet --- nutrition --- micronutrients --- macronutrients --- curcumin --- amino-acids --- vitamins --- minerals --- curcumin --- oxidative metabolites --- inflamm-aging --- cancer --- metabolic reprogramming --- direct protein binding --- IL-17 --- STAT3 --- SHMT2 --- ageing --- anti-cancer --- autophagy --- microbiota --- senescence --- senolytics --- curcumin --- transthyretin --- amyloidosis --- protein aggregation --- protein misfolding --- drug discovery --- curcumin --- renal cell cancer --- tumor growth --- tumor proliferation --- cell cycling --- curcumin --- reflux esophagitis --- gastroprotection --- gastric ulcer --- Helicobacter pylori --- gastric cancer --- curcumin --- complementary medicine --- cancer treatment --- supportive care --- antioxidants --- anti-inflamation --- ulcerative colitis --- Crohn’s disease --- necrotizing enterocolitis --- curcumin --- inflammatory bowel disease --- curcumin --- silica --- chitosan --- nanoparticles --- anti-tumor --- antioxidant activity --- n/a

Microstructure and Mechanical Properties of Structural Metals and Alloys

Author:
ISBN: 9783038975052 / 9783038975069 Year: Pages: 272 DOI: 10.3390/books978-3-03897-506-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Chemical Engineering
Added to DOAB on : 2019-06-26 08:44:06
License:

Loading...
Export citation

Choose an application

Abstract

The papers collected in this special issue clearly reflect the modern research trends in materials science. These fields of specific attention are high-Mn TWIP steels, high-Cr heat resistant steels, aluminum alloys, ultrafine grained materials including those developed by severe plastic deformation, and high-entropy alloys. The major portion of the collected papers is focused on the mechanisms of microstructure evolution and the mechanical properties of metallic materials subjected to various thermo-mechanical, deformation or heat treatments. Another large portion of the studies is aimed on the elaboration of alloying design of advanced steels and alloys. The changes in phase content, transformation and particle precipitation and their effect on the properties are also broadly presented in this collection, including the microstructure/property changes caused by irradiation.

Keywords

Mg–Sm–Zn–Zr --- dynamic precipitation --- microstructure --- mechanical property --- bimodal ferrite steel --- ultrafine-grained microstructure --- mechanical properties --- corrosion resistance --- abnormal grain growth --- grain boundary engineering --- electron backscattered diffraction --- growth rate --- Al metal matrix composites --- microstructure --- mechanical properties --- strengthening mechanism --- hot compression --- dynamic recovery --- dynamic recrystallization --- texture --- aluminum alloys --- Al-Fe-Si-Zr system --- microstructure --- hardness --- electrical conductivity --- metal–matrix composite --- high-pressure torsion --- microstructure evolution --- microhardness --- shape memory alloy --- columnar grain --- Cu-Al-Mn --- elastocaloric effect --- strain rate --- measuring temperature --- creep --- lead-free solder --- Sb solder --- Sn-8.0Sb-3.0Ag --- solder microstructure --- martensitic steels --- creep --- precipitation --- electron microscopy --- high-Mn TWIP steel --- cold rolling --- annealing --- recovery --- recrystallization --- strengthening --- austenitic 304 stainless steels --- sub-merged arc welding --- post-weld heat treatment --- aluminum alloys --- aging --- precipitation --- electrical resistivity --- mechanical properties --- ferritic steel --- irradiation --- nanoindentation --- hardness --- transmission electron microscopy (TEM) --- microstructure --- high-entropy alloys --- high-pressure torsion --- microstructure evolution --- twinning --- mechanical properties --- welded rotor --- weld metal --- impact toughness --- PWHT --- microstructure evolution --- Cu-Cr-Zr --- precipitation --- orientation relationship --- recrystallization --- annealing twins --- structural steel plate --- nonmetallic inclusions --- rare earth control --- M23C6 --- ion irradiation --- M6C --- amorphization --- RAFM steels --- hot stamping --- press hardening --- martensitic expansion --- force peak --- cycle time --- high-Mn steel --- deformation twinning --- dynamic recrystallization --- grain refinement --- work hardening --- in situ tensile testing --- super duplex stainless steel --- SDSS --- low-temperature --- ?-phase --- SEM --- EBSD --- microstructure analysis --- n/a

Listing 1 - 5 of 5
Sort by
Narrow your search