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Ultrafast Ultrasound Imaging

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ISBN: 9783038971276 9783038971283 Year: Pages: 184 DOI: 10.3390/books978-3-03897-128-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medical technology
Added to DOAB on : 2018-09-21 09:01:06
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Among medical imaging modalities, such as computed tomography (CT) andmagnetic resonance imaging (MRI), ultrasound imaging stands out due to itstemporal resolution. Owing to the nature of medical ultrasound imaging, it has beenused for not only observation of the morphology of living organs but also functionalimaging, such as blood flow imaging and evaluation of the cardiac function. Ultrafastultrasound imaging, which has recently become widely available, significantlyincreases the opportunities for medical functional imaging. Ultrafast ultrasoundimaging typically enables imaging frame-rates of up to ten thousand frames persecond (fps). Due to the extremely high temporal resolution, this enablesvisualization of rapid dynamic responses of biological tissues, which cannot beobserved and analyzed by conventional ultrasound imaging. This Special Issueincludes various studies of improvements to the performance of ultrafast ultrasound

Fatigue crack detection on structural steel members by using ultrasound excited thermography = Erkennung von Ermüdungsrissen in Stahlbauteilen durch ultraschallangeregte Thermografie

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Book Series: Berichte zum Stahl- und Leichtbau / Karlsruher Institut für Technologie, Versuchsanstalt für Stahl, Holz und Steine, Stahl- und Leichtbau ISSN: 21987912 ISBN: 9783731504177 Year: Volume: 3 Pages: XVI, 334 p. DOI: 10.5445/KSP/1000048191 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 19:59:17
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Ultrasound excitation of structural steel members leads to localised energy dissipation at existent fatigue cracks and thus allows for thermographic flaw detection. Essential effects on the defect-selective heating, such as flaw size, plate thickness, crack mouth opening or static preload, are systematically investigated. Laser vibrometry measurements of the crack edges, theoretical modelling of frictional heating and numerical simulations contribute to the understanding of the involved physics.

Ultrasound Elastography

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ISBN: 9783038979104 9783038979111 Year: Pages: 144 DOI: 10.3390/books978-3-03897-911-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-08-28 11:21:27
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The comparison between methods, evaluation of portal hypertension and many other questions are still open issues in liver elastography. New elastographic applications are under evaluation and close to being used in clinical practice. Strain imaging has been incorporated into many disciplines and EFSUMB guidelines are under preparation. More research is necessary for improved evidence for clinical applications in daily practice. The Special Issue published papers on recent advances in development and application of Ultrasound Elastography.

Ultrasound B-mode Imaging: Beamforming and Image Formation Techniques

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ISBN: 9783039211999 9783039212002 Year: Pages: 146 DOI: 10.3390/books978-3-03921-200-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:15
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Ultrasound medical imaging stands out among the other diagnostic imaging modalities for its patient-friendliness, high temporal resolution, low cost, and absence of ionizing radiation. On the other hand, it may still suffer from limited detail level, low signal-to-noise ratio, and narrow field-of-view. In the last decade, new beamforming and image reconstruction techniques have emerged which aim at improving resolution, contrast, and clutter suppression, especially in difficult-to-image patients. Nevertheless, achieving a higher image quality is of the utmost importance in diagnostic ultrasound medical imaging, and further developments are still indispensable. From this point of view, a crucial role can be played by novel beamforming techniques as well as by non-conventional image formation techniques (e.g., advanced transmission strategies, and compounding, coded, and harmonic imaging). This Special Issue includes novel contributions on both ultrasound beamforming and image formation techniques, particularly addressed at improving B-mode image quality and related diagnostic content. This indeed represents a hot topic in the ultrasound imaging community, and further active research in this field is expected, where many challenges still persist.

In Vivo Imaging in Pharmacological Research

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889452378 Year: Pages: 222 DOI: 10.3389/978-2-88945-237-8 Language: English
Publisher: Frontiers Media SA
Subject: Therapeutics --- Science (General)
Added to DOAB on : 2017-10-13 14:57:01
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The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (small molecule or macromolecule of natural or synthetic origin) with those targets, and to facilitate the study of the pharmacokinetics, pharmacodynamics and toxicity of an active agent in suitable models and in human subjects. The objective of this Research Topic is to highlight new developments and applications of imaging techniques with the objective of performing pharmacological studies in vivo, in animal models and in humans. In the domain of drug discovery, the pharmacological and biomedical questions constitute the center of attention. In this sense, it is fundamental to keep in mind the strengths and limitations of each analytical or imaging technique. At the end, the judicious application of the technique with the aim of supporting the search for answers to manifold questions arising during a long and painstaking path provides a continuous role for imaging within the complex area of drug discovery and development.

The Chemistry of Imaging Probes

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889455980 Year: Pages: 129 DOI: 10.3389/978-2-88945-598-0 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-01-23 14:53:43
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Over the past decades, the field of molecular imaging has been rapidly growing involving multiple disciplines such as medicine, biology, chemistry, pharmacology and biomedical engineering. Any molecular imaging procedure requires an imaging probe that is an agent used to visualize, characterize and quantify biological processes in living systems. Such a probe typically consists of an agent that usually produces signal for imaging purpose, a targeting moiety, and a linker connecting the targeting moiety and the signaling agent.Many challenging problems of molecular imaging can be addressed by exploiting the great possibilities offered by modern synthetic organic and coordination chemistry and the powerful procedures provided by conjugation chemistry. Thus, chemistry plays a decisive role in the development of this cutting-edge methodology.Currently, the diagnostic imaging modalities include Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Ultrasound (US), Nuclear Imaging (PET, SPECT), Optical Imaging (OI) and Photoacoustic Imaging (PAI). Each of these imaging modalities has its own advantages and disadvantages, and therefore, a multimodal approach combining two techniques is often adopted to generate complementary anatomical and functional information of the disease. The basis for designing imaging probes for a given application is dictated by the chosen imaging modality, which in turn is dependent upon the concentration and localization profile (vascular, extracellular matrix, cell membrane, intracellular, near or at the cell nucleus) of the target molecule. The development of high-affinity ligands and their conjugation to the targeting vector is also one of the key steps for pursuing efficient molecular imaging probes. Other excellent reviews, text and monographs describe the principles of biomedical imaging, focusing on molecular biology or on the physics behind the techniques. This Research Topic aims to show how chemistry can offer molecular imaging the opportunity to express all its potential.

Sensors for Ultrasonic NDT in Harsh Environments

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ISBN: 9783039284221 / 9783039284238 Year: Pages: 120 DOI: 10.3390/books978-3-03928-423-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2020-06-09 16:38:57
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In this Special Issue of Sensors, seven peer-reviewed manuscripts appear on the topic of ultrasonic transducer design and operation in harsh environments: elevated temperature, high gamma and neutron radiation fields, or the presence of aggressive chemicals. Motivations for these research and development projects are strongly focused on nuclear power plant inspections (particularly liquid-sodium cooled reactors), and nondestructive testing of high-temperature piping installations. It is anticipated that extensive use of permanently mounted robust transducers for in-service monitoring of petrochemical plants and power generations stations; quality control in manufacturing plants; and primary and secondary process monitoring in the fabrication of engineering materials will soon be made.

Extraction Strategies to Recover Bioactive Compounds, Incorporation into Food and Health Benefits

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ISBN: 9783039289691 / 9783039289707 Year: Pages: 94 DOI: 10.3390/books978-3-03928-970-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2020-06-09 16:38:57
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We are pleased to present this book, which is a reprint of articles from the Special Issue entitled “Extraction Strategies to Recover Bioactive Compounds, Incorporation into Food, and Health Benefits” published online in the open access journal Foods (ISSN 2304-8158) from 2019 to 2020 (available at: https://www.mdpi.com/journal/foods/special_issues/extraction). Firstly, this book gathers studies addressing several strategies applied to obtain bioactive products and extracts, not only from food matrices but also from agri-food byproducts, which can serve as new natural additives, nutraceuticals, and functional ingredients for pharmaceutical, cosmetics, and food industries. In particular, free and bound phenolic compounds are explored in buckwheat, sesame, and olive leafy byproducts. Overall, these studies outline new valorization methods and offer new opportunities for alternative practices in the agro-industrial sector that help to migrate toward a circular bioeconomy model. This book also presents studies that predict bioactive components in fruits through mathematical tools and support the formulation of a novel beverage rich in resveratrol, a phenolic compound whose bioactivity is well recognized.

Wine Aging Technologies

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ISBN: 9783038977483 Year: Pages: 120 DOI: 10.3390/books978-3-03897-749-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Science (General)
Added to DOAB on : 2019-04-05 10:34:31
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Wine aging is a desirable and valuable process, commonly used to improve wine quality, and traditionally carried out in oak wooden casks. The correct use of oak barrels and the ever-increasing demand for barrels in the different production areas of the world has led to a constant search for technological alternatives to reproduce the chemical and physical processes undergone by wines during their stay in barrels.The aim of this Special Issue is to publish a compilation of original research and revision works that cover different aspects of the ageing processes of wine in casks and other alternative systems that reproduce, with different technologies, the transformations that take place in the barrel.Important aspects to be addressed are:the type of technological solutions that exist for wine agingthe impact of these new technologies on the final productcomparison of the effect of emerging and traditional technologies on the wine ageddifferentiation of wines undergoing different systems to avoid fraudcharacterization of the new materials used in barrel productionaccelerated aging of wines with wood and oxygen

Catalytic, Photocatalytic and Electrocatalytic Processes for the Valorisation of CO2

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ISBN: 9783039217786 9783039217793 Year: Pages: 132 DOI: 10.3390/books978-3-03921-779-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:16
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Increasing attention is being paid to the development of effective technologies for the sequestration of CO2 and its storage. Hopefully, this will result in processes that can lead to its valorisation as a chemical, e.g., for the regeneration of fuels, but also for the production of intermediates. These are usually energy demands and rather slow processes, requiring energy input and catalysts. Some examples are the innovative strategies for the hydrogenation, photoconversion, or electroreduction of carbon dioxide. This book collects original research papers, reviews, and commentaries focused on the challenges related to the valorisation and conversion of CO2.

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