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Eating Disorders and Obesity: The Challenge for Our Times

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ISBN: 9783038979982 9783038979999 Year: Pages: 274 DOI: 10.3390/books978-3-03897-999-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-06-26 08:44:06
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Abstract

Eating Disorders have traditionally been considered apart from public health concerns about increasing obesity. It is evident that these problems are, however, related in important ways. Comorbid obesity and eating disorder is increasing at a faster rate than either obesity or eating disorders alone and one in five people with obesity also presents with an Eating Disorder, commonly but not limited to Binge Eating Disorder. New disorders have emerged such as normal weight or Atypical Anorexia Nervosa. However research and practice too often occurs in parallel with a failure to understand the weight disorder spectrum and consequences of co-morbidity that then contributes to poorer outcomes for people living with a larger size and an Eating Disorder. Urgently needed are trials that will inform more effective assessment, treatment and care where body size and eating disorder symptoms are both key to the research question.

Keywords

obesity risk --- mothers --- women --- young children --- socioecological --- obesity --- eating disorders --- binge eating --- dieting --- treatment --- the Roma --- nurse --- overweight --- obesity --- health education --- lifestyle factors --- nutrition --- cultural features --- spinal cord injury --- athlete --- energy availability --- nutrient deficiency --- low energy availability --- bone mineral density --- para athlete --- menstrual dysfunction --- Female Athlete Triad --- Relative Energy Deficiency in Sports (RED-S) --- binge eating --- questionnaire --- psychometric --- eating disorders --- obesity --- obesity --- weight loss --- bariatric surgery --- eating behaviour --- psychology --- Bulimia Nervosa --- binge-eating disorder --- Diagnostic and Statistical Manual of Mental Disorders --- International Classification of Diseases --- biofeedback --- EEG-Neurofeedback --- fMRI-Neurofeedback --- eating disorders --- psychophysiology --- eating disorders-related symptoms --- loss of control eating --- obesity --- BMI --- adolescent --- females --- family functioning --- energy intake --- physical fitness --- visceral adipose tissue --- obesity --- eating disorders --- nutrition --- physical activity --- exercise --- bulimia --- binge eating disorder --- feeding behavior --- cognition --- obesity --- event-related potential --- P3 --- children --- eating disorders --- eating behavior --- feeding practices --- obesity --- EEG --- frequency bands --- obesity --- brain activity --- impulsivity --- children --- eating disorders --- obesity --- prevention --- food industry --- food environment --- food policy --- executive function --- obesity --- binge-eating disorder --- food addiction --- addictive-like eating --- dietary patterns --- body satisfaction --- orthorexia nervosa --- students --- binge-eating disorder --- BED --- obesity --- binge-type eating --- neuromedin U receptor 2 --- NMUR2 --- nucleus accumbens --- ventral tegmental area --- usability study --- online health intervention --- adolescents --- school setting --- eating disorders --- overweight --- prevention --- engagement --- E-Mental Health --- bulimia nervosa --- binge eating disorder --- weight --- dieting --- treatment

Neuroproteomics

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ISBN: 9783039281060 9783039281077 Year: Pages: 318 DOI: 10.3390/books978-3-03928-107-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Neurology
Added to DOAB on : 2020-04-07 23:07:08
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The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry out meaningful MS/proteomics analyses on neural tissues and the technologies that are available to meet these challenges. The articles on Alzheimer’s disease, addiction, and schizophrenia illustrate how MS/proteomics technologies can be used to improve our ability to diagnose and understand the molecular basis for neurological diseases. Several articles will be of interest to investigators beyond the field of neurological disorders. The review on the discovery of biofluid biomarkers of neurodegenerative dementias will be of interest to investigators searching for other disease biomarkers. Similarly, the review on the role of neuroproteomics in elucidating mechanisms of drug addiction provides an overview of the utility of MS/proteomics approaches for addressing critical questions in addiction neuroscience that should be applicable to investigators involved in virtually any area of biomedical research. Likewise, the article on developing targeted MS approaches for quantifying postsynaptic density proteins will be useful for any investigator who wishes to design targeted assays for virtually any protein. Finally, the peroxidase-mediated proximity labeling technology, described in the article on mapping the proteome of the synaptic cleft, will be of interest to investigators interested in mapping other spatially restricted proteomes.

Keywords

proteomics --- basal ganglia --- synapses --- synapse specificity --- neuronal circuits --- axons --- dendrites --- neurodegeneration --- synapse --- postsynaptic --- proteome --- mass spectrometry --- protein interaction networks --- connectome --- neurodegeneration --- Alzheimer’s disease --- cerebrospinal fluid --- plasma --- serum --- proteomics --- biomarkers --- LC-MS/MS --- cocaine --- addiction --- cytokine --- neuroimmune --- ventral tegmental area --- peptidylglycine ?-amidating monooxygenase --- cilia --- mating --- signal peptide --- prohormone convertase --- carboxypeptidase --- matrix metalloproteinase --- subtilisin --- pherophorin --- morphine --- opioid receptors --- conformational antibody --- analgesia --- GPCR signaling --- phosphorylation --- AMPA receptor complex --- transmembrane AMPA receptor regulatory protein --- synaptic plasticity --- adolescence --- corticosterone --- proteomics --- yohimbine --- progressive ratio --- reinstatement --- ethanol --- nicotinic receptor --- CaMKII --- PKA --- quantitative phosphoproteomics --- mouse --- phosphorylation --- nicotine --- proteomics --- proteome --- mass spectrometry --- Alzheimer’s disease --- protein aggregation --- laser capture microdissection --- splicing --- U1 snRNP --- synapse --- synaptic cleft --- trans-synaptic adhesion --- proximity labeling --- SynCAM --- Cadm --- Receptor-type tyrosine-protein phosphatase zeta --- R-PTP-zeta --- Ptprz1 --- neuroproteome --- drug abuse --- neuropeptidomics --- phosphorylation --- interactome --- cell type --- neuroscience --- proteomics --- mass spectrometry --- neuron --- proximity labeling --- affinity chromatography --- neuroproteomics --- biotinylation --- amphetamine --- spinophilin --- protein phosphatase-1 --- dopamine --- striatum --- mass spectroscopy --- bioinformatics --- FGF14 --- voltage gated channels --- schizophrenia --- autism --- Alzheimer’s Disease --- sex-specific differences --- synaptic plasticity --- cognitive impairment --- excitatory/inhibitory tone --- n/a --- postsynaptic density --- PSD --- parallel reaction monitoring --- PRM --- targeted proteomics --- data-independent acquisition --- DIA --- quantitative mass spectrometry --- n/a

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MDPI - Multidisciplinary Digital Publishing Institute (2)


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english (2)


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2020 (1)

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