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Virus Discovery by Metagenomics: The (Im)possibilities

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453085 Year: Pages: 216 DOI: 10.3389/978-2-88945-308-5 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Microbiology
Added to DOAB on : 2018-02-27 16:16:45
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Abstract

Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.

Mycoviruses

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ISBN: 9783038979968 / 9783038979975 Year: Pages: 350 DOI: 10.3390/books978-3-03897-997-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2019-06-26 08:44:06
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Abstract

A virus (from the Latin word ‘v?rus’ meaning ‘venom’ or ‘poison’) is a microorganism invisible to the naked eye. Viruses can multiply exclusively by entering a cell and using the cell’s resources to create copies of themselves. As the origin of their name suggests, viruses are generally considered dangerous, harmful and often deadly. Some of the most well-studied and widely known viruses, such as HIV and influenza, infect humans. However, viruses can also infect animals, plants and microorganisms, including fungi. Many fungi are medically, ecologically and economically significant, for example, causing diseases to humans, plants and insects or being used in industry to produce bread, cheese, beer and wine. Viruses that infect fungi are called mycoviruses (from the Greek work ‘myco’, meaning ‘fungus’). Mycoviruses do not cause harm to or kill the infected fungus; in contrast, they are ‘friendly’ viruses and we can utilize them to control the growth, pathogenicity and toxin production of fungi. This book describes a range of different mycoviruses and their geographical distribution, transmission and evolution, together with their effects on the fungal hosts and how these are brought about.

Keywords

RNA silencing --- gemycircularvirus --- mycovirus --- antiviral --- dicer --- dsRNA mycoviruses --- multiplex PCR --- Aspergillus fumigatus chrysovirus --- Aspergillus fumigatus partitivirus-1 --- Aspergillus fumigatus tetramycovirus-1. --- Botrytis cinerea --- hypovirus --- fusarivirus --- hypovirulence --- infection cushion --- Botrytis cinerea --- Botrytis cinerea mymonavirus 1 --- Mymonaviridae --- dsRNA virus --- mycovirus --- capsid protein --- capsid structure --- virus evolution --- viral lineage --- ScV-L-A --- PcV --- PsV-F --- RnQV1 --- chrysovirus --- mycovirus --- Aspergillus --- A. fumigatus --- A. nidulans --- A. niger --- A. thermomutatus --- biocontrol --- Saccharomyces paradoxus --- Totiviridae --- dsRNA virus --- killer system --- Trichoderma atroviride --- Mycovirus --- Partitivirus --- Fusarium head blight --- mycovirus --- RNA genome --- mitovirus --- Tymovirales --- Ethiopia --- Sclerotinia minor --- endornavirus --- hypovirulence --- transmissibility --- biological control --- Chalara fraxinea --- Hymenoscyphus pseudoalbidus --- ash dieback --- Narnaviridae --- evolution --- invasive species --- horizontal virus transmission --- Brunchorstia pinea --- conifers --- mycovirus --- dsRNA --- ssRNA --- phylogeny --- evolution --- mycovirus --- Beauveria bassiana --- partitivirus --- victorivirus --- polymycovirus --- selection pressure --- recombination --- transmission --- mycovirus --- populations study --- Cryphonectria parasitica --- chestnut blight --- Castanea sativa --- biological control --- Mycovirus --- rice blast fungus --- Magnaporthe oryzae. chrysovirus 1 --- double-stranded RNA virus --- hypovirulence --- Rhizoctonia solani AG-1 IA --- mycovirus --- dsRNA --- Alphapartitivirus --- genomic structure analysis --- mycorrhizal fungi --- mycovirus --- mitovirus --- Rhizophagus --- hypovirus --- small RNA --- tRFs --- mycovirus --- fungal viruses --- dsRNA mycoviruses --- hypervirulence --- Leptosphaeria biglobosa quadrivirus --- Botrytis cinerea --- hypovirulence --- partitivirus --- conidiogenesis --- sclerogenesis --- mycovirus --- dsRNA --- sequencing --- killer toxin --- totivirus --- brown rot --- stone fruit --- Prunus --- mycovirus --- hypervirulence --- hypovirulence --- isogenic --- database mining --- Entomophthora --- Entomophthoromycotina --- fungal virus --- mitochondrion --- mycovirus --- virus discovery --- Mitovirus --- Narnaviridae --- n/a

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