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Nutrition and Eye Health

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ISBN: 9783039219902 9783039219919 Year: Pages: 242 DOI: 10.3390/books978-3-03921-991-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Science (General)
Added to DOAB on : 2020-01-30 16:39:46
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Abstract

Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies. Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES. The objective of this Special Issue on ‘Nutrition and Eye Health’ is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES.

Keywords

lutein --- RR-zeaxanthin --- mesozeaxanthin (RS zeaxanthin) --- light damage --- photoreceptor degeneration --- oxidative stress --- endoplasmic reticulum stress --- electroretinography --- advanced glycation end products --- chyrsin --- diabetic retinopathy --- endoplasmic reticulum --- retinal pigment epithelium --- visual cycle --- cataract --- phytoconstituents --- lens --- preclinical models --- drug discovery --- age-related macular degeneration --- gut-retina axis --- gut microbiota --- dietary habits --- micronutrients --- fish oil --- omega-3 polyunsaturated fatty acids --- personalised medicine --- Lactobacillus paracasei KW3110 --- retina --- light --- macrophage --- saffron --- Crocus Sativus L. --- crocin --- crocetin --- supplements --- anti-oxidant --- anti-inflammatory --- AMD --- diabetes --- glaucoma --- retina --- oxidative stress --- inflammation --- microvascular lesions --- neoangiogenesis --- polyphenols --- flavonoids --- carotenoids --- saponins --- rosmarinic acid --- sinapic acid --- lenses --- estrogen-deficient rats --- oxidative stress --- reduced glutathione --- omega-3 --- fatty acid --- diet --- dietary assessment --- clinical survey --- eye disease --- dry eye --- age-related macular degeneration --- food frequency questionnaire --- CODS --- clinical practice guidelines --- systematic reviews --- age-related macular degeneration --- nutritional supplements --- diet --- nutrition --- AGREE II --- Cucurbita argyrosperma --- corneal chemical burn --- angiogenesis --- corneal neovascularization (CNV) --- vascular endothelial growth factor (VEGF) --- interleukin-1? (IL-1?) --- cyclooxigenase-2 (COX-2) --- nuclear factor-kappaB (NF-?B) --- dietary antioxidants --- antioxidant supplements --- lens --- cataract --- n/a

Carotenoids and Human Health

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ISBN: 9783039218325 9783039218332 Year: Pages: 308 DOI: 10.3390/books978-3-03921-833-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2020-01-07 09:08:26
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Abstract

Carotenoids are a group of approximately 600 compounds synthesized by photosynthetic organisms. These pigments are abundant in fruits and vegetables, as well as in certain animal products such as eggs and salmon, being responsible for their colorful appearance. The bioactive properties of certain carotenoids in human health are clear, as some of these compounds have antioxidant properties and serve as the only precursors of vitamin A in nature. The aim of this Special Issue entitled “Carotenoids and Human Health” is to provide the scientific community with an updated perspective of this exciting and growing research area. We compiled 19 papers from some of the most prominent scientists in the carotenoid field, including seven literature reviews and 12 original publication, covering topics such as cancer, obesity, vision, cognitive function, and skin health.

Keywords

carotenoids --- lycopene --- gastric cancer --- H. pylori --- smoking --- case-control study --- Korea --- cancer-related cognitive impairment --- cognition --- carotenoid --- memory --- inflammation --- mango by-products --- lutein --- ?-carotene --- ?-tocopherol --- mangiferin --- food ingredients --- astaxanthin --- Akkermansia --- alcoholic fatty liver disease --- inflammation --- gut microbiota --- lycopene --- carotene --- retinoic acid --- retinoid --- vitamin A --- RAR --- RXR --- ?-carotene --- ?-carotene --- ?-cryptoxanthin --- carotenoids --- lutein --- provitamin A --- retinol --- vitamin A --- breastfeeding --- new-born --- full-term mothers --- preterm mothers --- xanthophylls --- carotenes --- lutein --- colostrum --- mature milk --- ?-Cryptoxanthin --- carotenoids --- Caenorhabditis elegans --- fat reduction --- oxidative stress --- transcriptomic analysis --- metabolic syndrome --- aging --- prostate cancer --- tomato --- lycopene --- androgen --- cell culture --- animal --- obesity --- hippocampus --- nutrition --- overweight --- carotenoids --- Phaeodactylum tricornutum --- microalgae --- fucoxanthin --- eicosapentanoic acid --- obesity --- browning --- brown adipose tissue --- carotenes --- xanthophylls --- bioavailability --- intestine --- membrane transporters --- Vitamin A --- adipocyte --- ?-carotene oxygenase 1 --- hypertension --- carotenoids --- tomato extract --- lycopene --- phytoene --- phytofluene --- bioavailability --- glaucoma --- antioxidants --- oxidative stress --- macular pigment --- lutein --- colourless carotenoids --- cosmeceuticals --- functional foods --- nutraceuticals --- nutricosmetics --- photoprotection --- phytoene --- phytofluene --- public health --- nutrition --- chronic disease --- lutein --- zeaxanthin --- lycopene --- beta-carotene --- alpha-carotene --- beta-cryptoxanthin --- adipocytes --- adipose tissue --- brain --- carotenoids --- obesity --- retinoids --- carotenoids --- bioactive compounds

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